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Course Criteria
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3.00 Credits
An honors course which parallels Chem 152. The topics are covered in greater depth than in Chem 152, and additional applications of chemistry are included. Three lectures weekly. Prerequisite: Chem 151/151L and consent of instructor. (spring semester)
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3.00 - 4.00 Credits
An introduction to the principles and practices of analytical chemistry with an emphasis on quantitative methods. Classical methods such as titrimetric and volumetric analyses as well as basic instrumental methods involving spectroscopy, electrochemistry, and chromatography will be performed. Some experiments will be of the project type. Two laboratory periods weekly. Prerequisites: Chem 151, 152 and Chem 151L, 152L. (fall semester)
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3.00 Credits
A two-semester introduction to basic organic chemistry. The relationship of structure and bonding in organic compounds to reactivity will be emphasized. Reactions will be discussed from mechanistic and synthetic perspectives. Three lectures weekly. Prerequisite: Chem 151, 152. (every year)
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1.00 Credits
This course is designed to follow the material presented in Chem 301, 302. Microscale experimental techniques will be emphasized. Experiments include: recrystallization, distillation, extraction, chromatography, spectroscopy, kinetics, multi-step syntheses, and structure determination. One laboratory period weekly. Prerequisite: Chem 151L, 152L and concurrent registration in Chem 301-302.
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3.00 Credits
This course covers modern physical chemistry, including atomic and molecular structure, and spectroscopy. Three lectures weekly. Prerequisites: Chem 151-152, Math 151, and Phys 270, or consent of instructor. Corequisite: Phys 271. (fall semester)
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3.00 Credits
This course focuses on the classical principles of thermodynamics, kinetics, and statistical mechanics. Three lectures weekly. Prerequisite: Chem 311 or consent of instructor. (spring semester)
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3.00 Credits
This course will apply the principles of thermodynamics, equilibria and kinetics toward biological systems. The course will begin with a description of the first, second and third laws of thermodynamics with special attention toward their application to proteins, nucleic acids and membranes. The course will then examine equilibrium phenomena and the associated thermodynamics. These principles will be applied toward the design and evaluation of inhibitors and drugs. In the final third of the course, principles of kinetics will be examined. Measurement of rate constants for complex biological processes including non-Michaelis-Menten enzyme kinetics, ligand binding off and on rates and ribozyme catalysis. Three lectures weekly. Prerequisites: Chem 151-152, Biol 225, Phys 270, and Math 151. Chem 311 and Chem 331 are strongly recommended. (spring semester)
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3.00 Credits
The structure, function, and metabolism of biomolecules. Structure and function of proteins, carbohydrates, lipids, nucleic acids, and important accessory molecules (cofactors and metal ions) are covered, as well as enzyme kinetics and mechanism, thermodynamics, metabolism, and the regulation of metabolism. Three lectures weekly. Prerequisite: CHEM 301, 302/301L, 302L. (every semester)
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3.00 Credits
An advanced laboratory course that focuses on techniques for the preparation and quantitative analysis of proteins and other biomolecules. Experiments will include preparation of buffers, production and purification of proteins, and analysis of protein structure and function. Two laboratory periods weekly. Corequisite: CHEM 331. Biol 300L is strongly recommended. (every semester)
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3.00 Credits
A survey of the roles of metallobiomolecules in organisms. The functions, structure, and modes of metal coordination of the more significant molecules are examined in detail and compared to those of model compounds. The standard physical techniques used in studying these complexes are discussed. Particular emphasis is given to the role of the metal ion(s) and how their inorganic properties affect the activity of the biological compound. Three lectures weekly. Prerequisites: CHEM 302. (may not be offered every year)
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