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Course Criteria
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4.00 Credits
The biochemical and molecular basis of plant genetic engineering to understand modern approaches to crop improvement. Prerequisites: BILD 1; Chem 140A. BIBC 102 and Chem 140B may be taken concurrently.
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4.00 Credits
The theory and applications of physical chemistry to biological molecules, process and systems and techniques used in biochemistry and physiology. Topics include reversible and irreversible thermodynamics, bioenergetics, energy coupling and transduction, solutions of macromolecules, sedimention, chromatography, electrophoresis, passive and active membrane transport, spectroscopy, and chemical kinetics. Three hours of lecture and one hour of recitation. Prerequisites: calculus and organic chemistry.
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4.00 Credits
The history of an organism can be found in its genome. Analyses of the primary sequences will be used to recognize families of genes that arose by duplication and divergence. Topics include comparisons of amino acid sequences and three dimensional structures and range from the oldest and most widely distributed proteins to modem mosaics. Where possible, specific motifs and folds will be traced to their ancestral beginnings. Prerequisites: BIBC 100, BIMM 100.
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4.00 Credits
Elaborates the relationship between diet and human metabolism, physiology, health, and disease. Covers the functions of carbohydrates, lipids, proteins, vitamins, and minerals, and discusses dietary influences on cardiovascular disease, diabetes, obesity, and cancer. Prerequisites: BIBC 102.
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4.00 Credits
Biochemical mechanisms of adaptation in organisms to the marine environment. Special emphasis will be on the effects of pressure, temperature, salinity, oxygen, and light on the physiology and biochemistry. Prerequisites: BIBC 102 or consent of instructor.
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4.00 Credits
An introduction to the principles of heredity emphasizing diploid organisms. Topics include Mendelian inheritance and deviations from classical Mendelian ratios, pedigree analysis, gene interactions, gene mutation, linkage and gene mapping, reverse genetics, population genetics, and quantitative genetics. Prerequisites: BILD 1.
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4.00 Credits
Students will implement forward and reverse genetic methodologies widely used in contemporary biological research, focusing primarily on model organisms. Lab work is complemented by computer work that includes utilization of genome sequence databases and basic bioinformatics. Prerequisites: BIMM 100. Attendance at the first lecture/lab is required. Nonattendance will result in the student’s being dropped from the course roster.
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4.00 Credits
The structure and function of cells and cell organelles, cell growth and division, motility, cell differentiation and specialization. Prerequisites: BIBC 100 or BIBC 102.
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6.00 Credits
A laboratory course in the application of cellular techniques to biological problems. The establishment, growth, transformation, immortalization, and senescence of mammalian cells will be studied at the molecular and the cellular level. Ten hours of laboratory. In addition to the formal lab hours listed above, there will be an average of two hours in which students will be required to work in the class laboratory to complete experiments and prepare for presentations. Prerequisites: BICD 110 (may be taken concurrently); BIBC 103 is strongly recommended. Attendance at the first lecture/lab is required. Nonattendance will result in the student’s being dropped from the course roster.
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4.00 Credits
This course will focus on various subcellular organelles, their function, protein traffic, disulfide bond formation, protein folding, assembly of macromolecular complexes, protein quality control, and cellular responses to misfolded proteins. The emphasis will be on experimental approaches and model systems for the analyses of these problems, and on the connection of these topics to human disease. Three hours of lecture and one hour of mandatory discussion of primary publications per week. Open to upper-division students only. Prerequisites: BICD 110 and BIMM 100.
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