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  • 42 620: Engineering Molecular Cell Biology

    12.00 Credits
    Carnegie Mellon University

    Cells are not only basic units of living organisms but also fascinating engineering systems that exhibit amazing functionality, adaptability, and complexity. Applying engineering perspectives and approaches to study molecular mechanisms of cellular processes plays a critical role in the development of contemporary biology. At the same time, understanding the principles that govern biological systems provides critical insights into the development of engineering systems, especially in the micro- and nano-technology. The goal of this course is to provide basic molecular cell biology for engineering students with little or no background in cell biology, with particular emphasis on the application of quantitative and system perspectives to basic cellular processes. Course topics include the fundamentals of molecular biology, the structural and functional organization of the cell, the cytoskeleton and cell motility, the mechanics of cell division, and cell-cell interactions. Pre-requisites: 21-260 Differential Equations, or 06-262 Mathematical Methods of Chemical Engineering, or 18-202 Mathematical Foundations of Electrical Engineering. Advanced undergraduate or graduate student standing is required. Prior completion of 03-121 Modern Biology is suggested but not required. Proficiency in basic computation such as MATLAB programming is expected.
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  • 42 640: Computational Bio-Modeling and Visulization

    12.00 Credits
    Carnegie Mellon University

    Biomedical modeling and visualization play an important role in mathematical modeling and computer simulation of real/artificial life for improved medical diagnosis and treatment. This course integrates mechanical engineering, biomedical engineering, computer science, and mathematics together. Topics to be studied include medical imaging, image processing, geometric modeling, visualization, computational mechanics, and biomedical applications. The techniques introduced are applied to examples of multi-scale biomodeling and simulations at the molecular, cellular, tissue, and organ level scales.
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  • 42 645: Cellular Biomechanics

    9.00 Credits
    Carnegie Mellon University

    This course discusses how mechanical quantities and processes such as force, motion, and deformation influence cell behavior and function, with a focus on the connection between mechanics and biochemistry. Specific topics include: (1) the role of stresses in the cytoskeleton dynamics as related to cell growth, spreading, motility, and adhesion; (2) the generation of force and motion by moot molecules; (3) stretch-activated ion channels; (4) protein and DNA deformation; (5) mechanochemical coupling in signal transduction. If time permits, we will also cover protein trafficking and secretion and the effects of mechanical forces on gene expression. Emphasis is placed on the biomechanics issues at the cellular and molecular levels; their clinical and engineering implications are elucidated. 3 hrs. lec. Prerequisite: Instructor permission. Prerequisites: None. Corequisites: None. Cross Listed Courses: 24-655 Notes: None. Reservations:
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  • 42 660: Surgery for Engineers

    9.00 Credits
    Carnegie Mellon University

    Students will interact with clinical practitioners and investigate the technological challenges that face these practitioners. All students must sign up for one of the three accompanying practicums: Clinical Neuroscience, Clinical Cardiovascular, or Clinical Orthopedic. Students will complete a final report on the practicum that will describe an important clinical problem that can be solved with a new technology or a significant optimization of an existing technology. Pre-requisite: 42-202 Physiology
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  • 48 050: Study Abroad

    0.00 Credits
    Carnegie Mellon University

    No course description available.
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  • 48 051: Study Abroad

    0.00 Credits
    Carnegie Mellon University

    No course description available.
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  • 48 095: Spatial Concepts for Non-Architects I

    9.00 Credits
    Carnegie Mellon University

    This course serves as an introduction to the spatial concepts of architecture for students from other disciplines. The course is focused entirely on project design work (this is not an historical survey, technical or lecture course). Projects will explore the design and experience of spatial environments through a series of creative investigations. The first half of the semester will focus on short projects, with each design investigation progressively building upon the previous exploration; these early projects will consist of both individual and group work. The second half of the semester will consist of one long term project to be created individually, incorporating students? personal theories of architecture. Studio work will be supported by group discussion based upon critical review of student work, readings, slide presentations, videos and films. Students are encouraged to explore their own areas of interest with respect to their work in class. Self-motivation, class attendance and an open mind is mandatory, however, no prior architectural, engineering or artistic experience is required. Students are expected to perform work both inside and outside of class. Students should be prepared to purchase various supplies throughout the course. This course is in partial fulfillment of requirements for an Architecture Minor.
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  • 48 100: Architecture Design Studio: Foundation I

    12.00 Credits
    Carnegie Mellon University

    This is the first course in the design studio sequence. As such, it establishes the foundation of exploration into the design process and provides the fundamental abilities required to represent the students? inductive and deductive ideas as it pertains to spatial thinking. The semester is divided into two halves: The first half of the semester is devoted to teaching fundamental skills which involve collaboration, experimentation, working at full size, testing, ecological research and basic architectural fundamentals such as drawing and making as they pertain to small scale design projects. These projects focus on teaching fundamentals such as point, line, plane and volume as well as fundamental drawing skills such as line types, plan, section, elevation, volumetric and analytical drawing. The design process then shifts to projects, which introduce the student to spatial thinking. Students are asked to explore the fundamental issues of space through geometry, spatial definition, spatial transparency, overlap and articulation. These projects are explored in both the studio setting as well as through a woodshop project. By the end of the semester students are given an elementary program, which is to adapt the students? spatial strategy to a specific landscape environment. By developing a relationship between the spatial enclosure, landscape, and the natural environment, the student is to show a basic understanding in spatial thinking through graphic, mock-up, physical and digital modeling.
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  • 48 105: Architecture Design Studio: Foundation II

    12.00 Credits
    Carnegie Mellon University

    The spring semester, Methods and Transformations in Space of the first year architecture program extends from experiences in the fall semester Methods and Transformations in Form. Architecture as a spatial practice is introduced. Design projects evolve from previous studies of structure surface and volume in plant and landscape paradigms. Systems and sequences previously explored in nature are developed in cultural contexts through a progressive series of projects. Mapping human behavior and studying architectural precedents create spatial temporal experiences and narratives. Architectural and interdisciplinary analyses launch each project as a vehicle for generative design strategies. Fluid connections between drawing (freehand and drafted) and modeling (physical, computer, and wood shop) are continued. The semester is divided into three primary design projects: WOODSHOP: The studios explicit relationship to the woodshop is expanded in this course. ROOM (Private) INTERIOR: This project introduces a group research project of architectural precedents as its analytical catalyst. The study of an interior space focuses the transition from form to that of space. PLACE (Public) BUILDING: This project uses, interdisciplinary, cultural research as its analytical formal catalyst. The study of a public infill building establishes architecture within an urban context and requires ability to create spatial sequences of public / private programmatic function. The process includes freehand drawing, model building, shade and shadow, digital modeling, and drafting.
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