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  • 42 203: Biomedical Engineering Laboratory

    9.00 Credits
    Carnegie Mellon University

    This laboratory course is designed to provide students with the ability to make measurements on and interpret data from living systems. The experimental modules reinforce concepts from 42-101 Introduction to Biomedical Engineering and expose students to four areas of biomedical engineering: biomedical signal and image processing, biomaterials, biomechanics, and cellular and molecular biotechnology. Several cross-cutting modules are included as well. The course includes weekly lectures to complement the experimental component. Prerequisites: 42-101 Introduction to Biomedical Engineering and 03-121 Modern Biology. Pre-med students should register for 03-206. Priority for enrollment will be given to students who have declared the Additional Major in Biomedical Engineering.
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  • 42 300: Junior BME Research Project

    3.00 - 12.00 Credits
    Carnegie Mellon University

    Research projects for juniors under the direction of a regular or courtesy BME faculty member. Arrangements may also be made via the Associate Head of BME for off-campus projects at local hospitals provided that a regular or courtesy BME faculty member agrees to serve as a co-advisor. The nature of the project, the number of units and the criteria for grading are to be determined between the student and the research advisor. The agreement should be summarized in a one-age project description with sign-off by the research advisor and a copy sjbmitted for review and filing to the student's academic advisor. A final written report or oral presentation of the results is required. Units may vary from 3 to 12 according to the expected time commitment.
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  • 42 311: Polymeric Biomaterials

    9.00 Credits
    Carnegie Mellon University

    This introductory course will address basic and applied concepts of polymers as biomaterials. The students will be exposed to both fundamental synthetic mechanisms of polymers and their physical and chemical properties. Specific emphasis will be placed on biodegradation mechanism, mechanical properties and surface chemistry of polymeric materials. Cellular interactions with various surfaces and immunological responses will be covered. Applications of biomaterials to be discussed include tissue engineering and artificial organs. Pre-requisite: None, but 09-105 Introduction to Modern Chemistry and 42-101 Introduction to Biomedical Engineering will be useful. Cross-listed with 27-311
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  • 42 321: Cellular and Molecular Biotechnology

    9.00 Credits
    Carnegie Mellon University

    This course will provide students with an introduction to biotechnology in an engineering context. The focus will be on using microorganisms to prepare therapeutically and technologically relevant biochemicals. Topics to be covered include cellular and microbial metabolism, recombinant DNA methodologies, bioreactor design, protein separation and purification, and systems approaches to biotechnology. Prerequisites: (42-202 Physiology OR 03-121 Modern Biology OR 03-232 Biochemistry) AND (06-262 Mathematical Methods of Chemical Engineering OR 21-260 Differential Equations) OR permission of instructor.
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  • 42 334: Introduction to Computational Biology

    12.00 Credits
    Carnegie Mellon University

    A general introduction to computational tools for biology, divided into two modules. The computational molecular biology/genomics module examines sources and archival of biological data. Specific topics to be covered include sequence data, searching and alignment, structural data, genome sequencing, genome analysis, genetic variation, gene and protein expression, and biological networks and pathways. The computational cell biology module includes biological modeling and image analysis. Topics include computer models of population dynamics, biochemical kinetics, cell pathways, neuron behavior, mutation, morphological image analysis, image classification and image-based models. This course is intended primarily for biological sciences or biomedical engineering majors at the undergraduate or graduate level who have not had extensive prior experience with computer science or programming. Students may not take both 03-310/42-334 and either 03-311 or 03-312 for credit. Pre-requisites: 03-121 Modern Biology or instructor permission. This class is cross-listed with 03-310.
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  • 42 341: Introduction to Biomechanics

    9.00 Credits
    Carnegie Mellon University

    This course provides a general survey of the application of solid mechanics and rigid body dynamics to the study of the human cardiovascular and musculoskeletal systems. The mechanical properties and behavior of heart, blood vessel, bone, muscle and connective tissues are discussed and methods for the analysis of human motion are developed. Both analytic and experimental results are presented through readings from reports in recent journals and the relevance of these results to the solution of unsolved problems is highlighted. The development of appropriate models for particular problems is also considered. Pre-requisites: 21-260 Differential Equations AND (24-262 Stress Analysis OR 12-331 Solid Mechanics OR equivalent). Useful, but not required: 24-141 Statics and Dynamics AND 24-202 Mechanics of Deformable Solids.
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  • 42 400: Senior BME Research Project

    3.00 - 18.00 Credits
    Carnegie Mellon University

    Research projects for seniors, under the direction of a regular or courtesy BME faculty member. Arrangements may also be made via the Associate Head of BME for off-campus projects at local hospitals provided that a regular or courtesy BME faculty member agrees to serve as a co-advisor. The nature of the project, the number of units and the criteria for grading are to be determined between the student and the research advisor. The agreement should be summarized in a one-page project description with sign-off by the research advisor and a copy submitted for review and filing to the student's academic advisor. A final written report or oral presentation of the results is required. Units may vary from 3 to 12 according to the expected time commitment.
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  • 42 401: Foundation of BME Design

    3.00 Credits
    Carnegie Mellon University

    42-401 Foundations of Biomedical Engineering Design (Fall, 3 units) (Precursor to 42-402) This course introduces Biomedical Engineering students to the design of useful biomedical products. Students will learn to identify product needs, how to specify problem definitions and to use project management tools. Methods to develop creativity in design will be introduced. Students will form project teams and select a project to be completed during the following semester in 42-402. This course culminates in the completion of a design brief. Prerequisite: Senior standing in Biomedical Engineering. Co-requisite: 42-101.
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  • 42 402: BME Design Project

    9.00 Credits
    Carnegie Mellon University

    42-402 Biomedical Engineering Design Project (9 units, Spring) This course focuses on integrated product development for biomedical products. Teams will consist of a variety of Biomedical Engineering students. The course consists of modules including the development of a project plan, background research, hazard analysis, setting product specifications based on user requirements, detailed design and analysis, prototype development and final documentation and presentation. Additional relevant professional development topics are also covered, including technical public speaking, proposal preparation, personal time management, and other topics. All products developed will respond to the needs of appropriate market segments; resulting products will be deemed safe, effective, useful, usable and desirable by those segments. Students will produce a form model, functional prototype, marketing plan, and manufacturing plan of their product. Prerequisite: 42-401 (3 units, Fall) Foundations of Biomedical Engineering Design
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  • 42 419: Biomaterial/Host Interactions

    12.00 Credits
    Carnegie Mellon University

    The goal of this course is to provide students with hands-on experience in investigating host responses to materials. Implant studies of tissue-engineering materials will be performed using animal models in a laboratory setting, and students will gain experience in the analysis of host responses. Material biocompatibility and tissue regeneration will be addressed. Characterization techniques will include histology, real-time polymerase chain reaction, and immunofluorescent staining. Laboratory work will be complemented with lectures. Prerequisite: junior or senior standing in Biomedical Engineering, or consent of instructor.
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