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Course Criteria
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12.00 Credits
This course is designed to be taken as a sequel to 03-343. Experiments cover a variety of methods for investigating the structure and function of biological molecules. Experimental methods with proteins, enzyme kinetics, lipids, spectroscopy, and isolation and quantization of biological molecules are covered. During several experiments, students design their own projects. Experimentation using living organisms and/or their tissues, cells or molecules is an essential component of this course.
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12.00 Credits
This laboratory is designed to teach concepts and experimental methods in cell and developmental biology. Students work with a variety of organisms to examine how cells traverse development from rapidly dividing, undifferentiated cells, through cell commitment and the establishment of spatial and temporal patterns of gene expression, to the specific characteristics and responses of terminally differentiated cells. The course makes extensive use of video microscopy with phase contrast, DIC and fluorescence microscopes. Biochemical, immunological and molecular biological techniques are used to probe the molecules and processes of cells undergoing development. Experimentation using living organisms and/or their tissues, cells or molecules is an essential component of this course.
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9.00 Credits
Developmental biology is the study of how organisms arise from a single cell ? the fertilized egg. The molecular pathways that control development also underlie many human diseases. Developmental biology encompasses stem cell biology, cell-cell signaling, regulation of gene expression, gene networks, morphogenesis, and cell/tissue differentiation. This course serves as an introduction to the major concepts, experimental methodologies, research questions, and model organisms in developmental biology.
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9.00 Credits
Modern neuroscience is an interdisciplinary field that seeks to understand the function of the brain and nervous system. This course provides a comprehensive survey of systems neuroscience, a rapidly growing scientific field that seeks to link the structure and function of brain circuitry to perception and behavior. This course will explore brain systems through a combination of classical, Nobel prize-winning data and cutting edge primary literature. Topics will include sensory systems, motor function, animal behavior and human behavior in health and disease. Lectures will provide fundamental information as well as a detailed understanding of experimental designs that enabled discoveries. Finally, students will learn to interpret and critique the diverse and multimodal data that drives systems neuroscience.
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9.00 Credits
This course examines the principles that govern the developmental assembly of a complex nervous system. Topics range from the earliest steps of induction of neural tissue and birth of neurons to the plasticity within developing circuits and the development of behavior. By the end of this course students should be able to describe the major steps in neural development and to interpret key experiments using vertebrate and invertebrate models have helped to elucidate these steps. This course is taught on the University of Pittsburgh campus by faculty from Carnegie Mellon and Pitt.
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9.00 Credits
The concepts and methods of virology are covered, with emphasis on animal viruses, within the framework of cell biology, genetics, molecular biology, immunology, pathology, and epidemiology. The strategies that a wide variety of different DNA and RNA viruses, including some new and emerging ones, use to replicate and express their genomes during infection of host cells will be examined in some detail. The effects that viruses inflict on these cells will also be examined, as will some of the host cell responses generated by such virus-cell interactions, including interferon induction, the antiviralresponse generated by interferon, and oncogenic transformation. In addition, anoverview of procedures used for prevention and treatment of viral diseases via vaccinesand antiviral drugs, respectively, will be presented, as will a brief discussion of viroids and prions, and the characteristics of these agents which distinguish them from viruses.
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9.00 Credits
This course offers the student a comprehensive view of modern immunology at the molecular and cellular level. The first half of the course presents the fundamentals of immunology, beginning with innate immunity, followed by a discussion of the structure and function of important molecules in the immune system, such as antibodies, major histocompatibility antigens, complement, and the T-cell receptor. This portion of the course is concluded with a discussion of the development and function of the cellular immune response. The second half of the course is focused on applied immunology and discusses hypersensitivity, autoimmunity, immunodeficiencies, tumor immunology, infectious disease, and transplantation immunology. Presentations at the end of the course provide an opportunity for the student to explore additional topics in contemporary immunology.
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9.00 Credits
This course will provide an introduction to microorganisms, with an emphasis on their scientific, societal, and global impact. Specific topics include basic principles of microbiology, introduction to molecular biology, genetics of microorganisms, microbial genomics and diversity, eukaryotic microorganisms, microbial metabolism, biotechnology, infectious diseases, and antimicrobial compounds.
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6.00 Credits
In this course, you will gain experimental experience with key concepts in microbiology (eg: taxonomy, antibiotic resistance, changes in morphology, secretion of metabolites into media, plasmids, medical implications, etc.); however, you will explore these concepts in the lab by using both standard and nonstandard state-of-the-art equipment (eg: flow cytometer, atomic force microscope, fluorescence/bright-field/phase-contrast light microscope, light scattering, etc.).
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1.00 - 3.00 Credits
The purpose of this seminar series is to update biology undergraduates about university and departmental functions, seminars, etc. that are pertinent or useful. In addition, research talks by faculty and undergraduates will be used to introduce students to the research being conducted in faculty laboratories. Additional topics may include graduate and medical school applications, career options, topics in the press, and important scientific discoveries.
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