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Course Criteria
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3.00 Credits
Prerequisites: BIOL W3004 and BIOL W3005 Neurobiology offers both a source of knowledge to inform the creation of law and a direct challenge to the underlying philosophies of law. As a recent example, the Supreme Court cited research on child brain development in their decision that child convicts should not receive life imprisonment without parole. But neuroscience reaches beyond criminal law, as it has been used to argue for limiting free speech, given the consequences of some forms of speech on their receiver. This course closely examines the most recent developments in neurobiology and the legal shifts they have generated. The focus will be on analyzing primary literature in the sciences as well as legal cases and scholarship. Because of its interdisciplinary nature, this course will benefit students considering careers in science, law, or policy.
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3.00 Credits
Prerequisites: Introductory biology course at Columbia, AP Biology, or permission of the instructor. This course covers selected topics in genetics and development, with special emphasis on issues that are relevant to contemporary society. Lectures and readings will provide students with the scientific knowledge to understand how genes regulate development, and how alterations in genes lead to abnormal development and disease. Interspersed workshops will allow students to research and discuss the ethical and societal impact of specific topics (e.g. in vitro fertilization, steroid use, and stem cell therapy). Science Requirement: Partial Fulfillment.
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3.00 Credits
Experiments focus on genetics and molecular biology, with an emphasis on data analysis and experimental techniques. The class also includes a study of mammalian anatomy and histology. Each section is limited to 28 students. Lab Fee $150.
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4.00 Credits
Prerequisites: one year of biology; a course in physics is highly recommended. Lecture and recitation. This is an advanced course intended for majors providing an in depth survey of the cellular and molecular aspects of nerve cell function. Topics include the cell biology and biochemistry of neurons, ionic and molecular basis of electrical signals, synaptic transmission and its modulation, function of sensory receptors. Although not required, it is intended to be followed by Neurobiology II (see below). The recitation meets once per week in smaller groups and emphasizes readings from the primary literature. Discussion Section Required.
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4.00 Credits
Neurobiology II: Development & Systems Prerequisites: Biology W3004, one year of biology or instructor's permission. This course is the "capstone" course for the Neurobiology and Behavior undergraduate major at Columbia University and will be taught by the faculty of the Kavli Institute of Brain Science (http://www.kavli.columbia.edu/). It is designed for advanced undergraduate and graduate students. Knowledge of Cellular Neuroscience (how an action potential is generated and how a synapse works) will be assumed. It is strongly recommended that students take w3004 Neurobiology 1: Molecular and Cellular Neuroscience, or a similar course, before enrolling in w3005. Students unsure about their backgrounds should check a representative syllabus of w3004 on the w3004 website (http://www.columbia.edu/cu/biology/courses/w3004/). Website for w3005: http://www.columbia.edu/cu/biology/courses/w3005/index.html
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3.00 Credits
Prerequisites: Biol C2005 & C2006 or F2401 & F2402, or the instructor's permission. Major physiological systems of vertebrates (circulatory, digestive, hormonal, etc.) with emphasis on cellular and molecular mechanisms and regulation. Readings include research articles from the scientific literature.
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3.00 Credits
Prerequisites: One 3000 level course in Cell Biology or Biochemistry or the instructor's permission. This course will present a quantitative description of the cellular physiology of excitable cells (mostly nerve and muscle). While the course will focus on examining basic mechanisms in cell physiology, there will be a thread of discussion of disease mechanisms throughout. The end of each lecture will include a discussion of the molecular mechanisms of selected diseases that relate to the topics covered in the lecture. The course will consist of two lectures per week. This course will be of interest to advanced (3000-4000 level)undergraduates that aim to pursue careers in medicine as well as those that will pursue careers in biomedical research. This course will also be of interest to graduate students desiring an introduction to the cellular physiology of nerve and muscle.
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3.00 Credits
Prerequisites: BIOL C2005-C2006 or equivalent Come discover how the union of egg and sperm triggers the complex cellular interactions that specify the diverse variety of cells present in multicellular organisms. Cellular and molecular aspects of sex determination, gametogenesis, genomic imprinting, X-chromosome inactivation, telomerase as the biological clock, stem cells, cloning, the pill and cell interactions will be explored, with an emphasis on humans. Original research articles will be discussed to further examine current research in developmental biology. BIOL W3022_001_2007_1">
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3.00 Credits
Students may receive credit for W3031 or C3032, but not both due to overlap in course content. General course in genetics and genomics dealing with principles of gene structure, function, regulation and transmission. Historical development, experimental basis of current knowledge, and roles of model organisms are stressed. Includes a thorough understanding of disease gene discovery, and an introduction to topics in developmental, cancer and population genetics.
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3.00 Credits
Prerequisites: genetics or molecular biology. For upper-level undergraduates. The course covers techniques currently used to explore and manipulate gene function and their applications in medicine and the environment. Part I covers key laboratory manipulations, including DNA cloning, gene characterization, association of genes with disease, and methods for studying gene regulation and activities of gene products. Part II also covers commercial applications, and includes animal cell culture, production of recombinant proteins, novel diagnostics, high throughput screening, and environmental biosensors.
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