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CHM 355: Physical Chemistry for Life Sciences
4.00 Credits
Wilkes University
An introduction to traditional physical chemistry topics, including additional topics related to life sciences. Laws of thermodynamics, equilibria, kinetics, and spectroscopy will be discussed in terms of their application to life sciences. Four hours of lecture per week.
Prerequisite:
[[CHM-114]] with a grade of 2.0 or better, [[CHM-116]] with a grade of 2.0 or better, and [[PHY-202]]
Corequisite:
[[CHM-357]]
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CHM 355 - Physical Chemistry for Life Sciences
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CHM 357: Physical Chemistry for Life Sciences Lab
1.00 Credits
Wilkes University
The laboratory experiments emphasize concepts presented in [[CHM-355]]. Course includes experimental work, analysis of a research article, and computer simulations relevant to life sciences. One three-hour laboratory pre week.
Prerequisite:
[[CHM-355]]
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CHM 357 - Physical Chemistry for Life Sciences Lab
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CHM 361: Biochemistry: Structure and Function
3.00 Credits
Wilkes University
This course presents a study of the physical and chemical properties of proteins, nucleic acid, fatty acids, and carbohydrates, emphasizing the relationship between the chemical structure and the biological function. The course includes the physical methods of biochemistry, enzyme kinetics, bioenergetics, and nucleic acid transcription and translation. Three hours of lecture per week.
Prerequisite:
[[CHM-232]] with a grade of 2.0 or better
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CHM 361 - Biochemistry: Structure and Function
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CHM 362: Biochemistry: Metabolism
3.00 Credits
Wilkes University
This course presents a study of the catabolism and anabolism of carbohydrates, fatty acids, and amino acids. The course emphasizes the regulation and integration of major metabolic pathways, including glycolysis, the Krebs cycle, electron transport, gluconeogenesis, pentose phosphate pathway, fatty acid metabolism, and amino acid metabolism. Three hours of lecture per week.
Prerequisite:
[[CHM-232]] with a grade of 2.0 or better
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CHM 362 - Biochemistry: Metabolism
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CHM 363: Biochemistry Laboratory
1.00 Credits
Wilkes University
Laboratory experiments, which emphasize biochemical techniques used in isolation and characterization of macromolecules. Included in the course are various chromatographic techniques, electrophoresis, spectrophotometry, and classic biochemical methods. Laboratory, three hours a week. Click here for course fee.
Prerequisite:
Prerequisite or Corequisite: [[CHM-361]] or permission of instructor.
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CHM 363 - Biochemistry Laboratory
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CHM 365: Medical Biochemistry
4.00 Credits
Wilkes University
Introduction to basic biochemistry concepts, focusing on the structure and function of vitamins, proteins, and lipids, as well as bioenergetics and major catabolic pathways. The catabolism of carbohydrates, fats and amino acids, including reactions and regulation, will be discussed. Common metabolic pathways of drugs, enzyme induction and metabolism down regulation will also be presented. Four hours of lecture per week. Cross-listed with [[PHA-365]] and [[BEGR-465]].
Prerequisite:
[[CHM-232]] or [[CHM-235]] with a grade of 2.0 or better, or permission of the instructor
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CHM 365 - Medical Biochemistry
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CHM 370: CHM 371,CHM 372 Integrated Laboratories I, II, III
1.00 - 2.00 Credits
Wilkes University
Laboratory experiments related to the five major areas of chemistry. Labs will be chosen in order that students might demonstrate proficiency in each of the required areas. Labs will include synthesis, isolation, and characterization of chemical compounds, spectroscopy, kinetics, calorimetry, chromatography, electrophoresis, and other chemical and biochemical methods. Three hours of laboratory per week per credit hour. Click here for course fee.
Prerequisite:
[[CHM-232]] with a grade of 2.0 or better, [[CHM-234]] with a grade of 2.0 or better and [[CHM-341]] with a grade of 2.0 or better
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CHM 370 - CHM 371,CHM 372 Integrated Laboratories I, II, III
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CHM 377: Introduction to Toxicology
3.00 Credits
Wilkes University
An introduction to toxicology, including its history, types of poisons, their mode of operation and the biochemistry of detoxification. Environmental problems caused by toxic contaminants will be discussed. This course is offered in the fall semester of even numbered years.
Prerequisite:
[[CHM-232]] , [[CHM-234]] and [[BIO-226]] or instructor permission.
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CHM 377 - Introduction to Toxicology
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CHM 379: Medicinal Chemistry
3.00 Credits
Wilkes University
The course provides an introduction to drugs, their action and discovery. Topics covered include drug structure & solubility, structure-activity & quantitative structure relationships, drugs from natural sources, the role of biological membranes in drug delivery, the role of receptors & messengers, enzymes, and an introduction to drug and analogue synthesis. This course is offered in the fall semester of odd numbered years.
Prerequisite:
[[CHM-232]] , [[CHM-234]] and [[BIO-226]] or instructor permission.
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CHM 379 - Medicinal Chemistry
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CHM 380: NMR Spectroscopy
3.00 Credits
Wilkes University
This course explores the capabilities of the Chemistry Department's NMR spectrometer, and provides a groundwork in NMR theory beyond the level covered in the sophomore organic course. Topics covered include hardware, data processing, chemical shifts and coupling, one- and two-dimensional pulse sequences, dynamic NMR, the NOE effect, and gradient methods. Offered in alternate years.
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CHM 380 - NMR Spectroscopy
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