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Biology 404: Senior Research Tutorial in Molecular Microbiology
3.00 Credits
Haverford College
NA I.Okeke Studies in bacterial genetics and pathogenesis. Molecular methods will be used to identify and characterize features of diarrhea-causing Escherichia coli that are absent in commensal strains. Laboratory work is supplemented by readings from current literature. Prerequisite: Consent of the instructor.
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Biology 404 - Senior Research Tutorial in Molecular Microbiology
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Biology 406: Senior Research Tutorial in Cellular Immunology
3.00 Credits
Haverford College
NA J.Owen Faculty- guided student research is supplemented by weekly lab meetings at which students present papers from the original literature. The end phase of an immune response is characterized by cell fate decisions in which actively engaged lymphocytes either undergo apoptosis or differentiate into memory cells. Students in this laboratory study and manipulate the expression of pro-and anti-apoptotic molecules in order to understand the process as it affects both B and T cells. Prerequisite: Consent of the instructor.
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Biology 406 - Senior Research Tutorial in Cellular Immunology
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Biology 407: Senior Research Tutorial in Cell Motility and the Cytoskeleton
3.00 Credits
Haverford College
NA K.Johnson Studies on the structure and function of microtubules and other cytoskeletal components. Techniques employed include the generation of mutants and their characterization by genetic analysis; the manipulation of DNA, RNA and protein, including studies of transformation and expression; and the production of antibodies and their use in immunofluorescence and immunoelectron microscopy. Laboratory work is supplemented by readings from the current literature. Prerequisite: Consent of instructor.
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Biology 407 - Senior Research Tutorial in Cell Motility and the Cytoskeleton
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Biology 408: Senior Research Tutorial on Life and Death Decisions of Developing Lymphocytes
3.00 Credits
Haverford College
NA J.Punt The fate of developing T cell depends on the interactions it experiences through its T cell receptor as it traffics through the thymus. Interestingly, identical interactions can have markedly different consequences depending on the T cell developmental stage. Immature T cells (thymocytes) respond to strong T cell receptor signals by dying, while their direct descendents, mature T cells, respond to the very same stimulation by proliferating. We are working to determine the molecular reasons behind this difference in responsiveness. By identifying and comparing the intracellular signals experienced by immature and mature T cells we are working to solve this developmental mystery. Laboratory work is supplemented by readings from current literature. Prerequisite: Consent of the instructor.
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Biology 408 - Senior Research Tutorial on Life and Death Decisions of Developing Lymphocytes
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Biology 409: Senior Research Tutorial in Molecular Neurobiology
3.00 Credits
Haverford College
NA A.Morris The developing nervous system of vertebrate embryos rapidly becomes patterned into distinct domains of neural cell differentiation. In order to identify what genes are responsible for the establishment of this pattern, a variety of molecular screening techniques are employed. The expression pattern of these genes is then determined by in situ hybridization and their function analyzed in vivo and in vitro, using microinjection and biochemical assays. Laboratory work is supplemented by readings from the current literature. Prerequisite: Consent of instructor.
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Biology 409 - Senior Research Tutorial in Molecular Neurobiology
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Biology 410: Senior Research Tutorial at Off-Campus Research Labs
3.00 Credits
Haverford College
NA R.Fairman Research in an area of cell, molecular, or development biology is conducted under the supervision of a member of a nearby research laboratory who has volunteered time and space for a Haverford student. All students enrolled in Biology 410 must have a designated on-campus, as well as an off-campus supervisor. Prerequisite: Biology 300 and consent of both the department and the off-campus supervisor.
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Biology 410 - Senior Research Tutorial at Off-Campus Research Labs
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Biology 411: Senior Research Tutorial on The Control of Cell Shape:Molecular & Evolutionary Approaches
3.00 Credits
Haverford College
NA R.Hoang All embryos undergo a series of highly elaborate cell movements to produce their final shape and form. Understanding the molecular basis of these movements provides important insight into the underlying molecular mechanisms, and enables us to ask how changes in these mechanisms give rise to differences between organisms. Students therefore approach this subject from both molecular and evolutionary perspectives. Using the fruit fly as a model system, we are looking inside cells to ask how intricate changes to the cytoarchitecture of individual cells drive movements of entire layers of cells. We hope to further understand how these same developmental processes go awry in situations of human disease (e.g. cancer metastasis). We are also examining cell movements in a variety of insects to ask how the developmental mechanisms themselves evolve and change. Projects draw on a variety of techniques including cell and molecular biology, embryology, genetics, genomics and cell imaging. Laboratory work is supplemented by readings from the current literature. Prerequisite: Consent of instructor.
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Biology 411 - Senior Research Tutorial on The Control of Cell Shape:Molecular & Evolutionary Approaches
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Biology 480: Independent Study
3.00 Credits
Haverford College
NA R.Fairman
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Biology 480 - Independent Study
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Biology 493: Interdisciplinary Examinations of Biologically Significant Research
3.00 Credits
Haverford College
NA (Cross-listed in Chemistry and Physics and Psychology) J.Punt Seminar for HHMI Scholars and any junior or senior science major committed to an interdisciplinary approach to the study of original research.
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Biology 493 - Interdisciplinary Examinations of Biologically Significant Research
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Biology 499: Senior Department Studies
3.00 Credits
Haverford College
NA J.Owen Participation in the department's Philip's Visitors Program; attendance at seminars by visiting speakers; senior seminar meetings, consisting of presentation and discussion of research plans and research results by students and faculty; and students' presentations of papers on contemporary developments in experimental biology. Prerequisite: Consent of Department.
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Biology 499 - Senior Department Studies
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