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Course Criteria
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3.00 Credits
NA Staff A study of the mechanisms by which individual cells in a multicellular organism communicate via the exchange of molecular signals. The course will focus on the release of molecular messengers, their interactions with specific receptor-bearing target cells of appropriate responses such as increased metabolic activity and/or cell division. Considerable attention is paid to the biochemistry of plasma and internal cell membranes and pathways are discussed from a disease perspective. Prerequisite: Biology 200 or its equivalent or consent of instructor.
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3.00 Credits
NA P.Meneely The development of selected model organisms, both invertebrate and vertebrate, is used to examine the principles of fertilization, cleavage, gastrulation, morphogenesis, and pattern formation. Mechanisms by which genetic information is stored, segregated and activated during cell determination and differentiation are explored. Prerequisite: Biology 200 and 301 or consent of instructor.
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3.00 Credits
NA J.Punt This course will provide an introduction to the rapidly expanding discipline of immunology. Students will learn about the molecular and cellular basis of the immune response through the study of the genetics and biochemistry of antigen receptors, the biochemistry of immune cell activation, the cell physiology of the immune system, immune memory, immune tolerance induction and immune-mediated cell death. Prerequisite: Biology 200 or consent of instructor.
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3.00 Credits
NA A.Morris This course will focus on molecular approaches to study nervous system development, function and pathology. Topics including the generation of neurons and glia, electrical signaling, learning and memory and Alzheimer's disease will be discussed using examples from a variety of model systems. Prerequisite: Biology 200 or consent of instructor.
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3.00 Credits
NA I.Okeke A study of prokaryotic biology with emphasis on cell structure, gene organization and expression, which will incorporate selected readings from the primary literature. Topics include the bacterial and viral cell structure, the genetics of bacteria and bacteriophage, gene regulation, horizontal gene transfer and microbial genomics. The course will be taught via lecture, class presentation and discussion, and workshops. Prerequisite: Biology 200 and Chem 221a or consent of the instructor.
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3.00 Credits
NA R.Hoang This course introduces important links between developmental and evolutionary biology. Genetic changes that produce variations between organisms are an important aspect of evolutionary change. Since development can be viewed as the process that links genetic information to the final form of an organism, the fields of development and evolution clearly impact one another. We will look at Drosophila and zebrafish, where developmental mechanisms have been elucidated in remarkable detail. We will then look beyond these model systems to comparative studies that examine development in a range of organisms, considering how these provide insight into evolutionary mechanisms, and how underlying differences in development may account for the differences we see between organisms. Prerequisite: Biology 200 or consent of instructor.
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3.00 Credits
NA A.Morris A half-semester lab course introducing molecular and cellular approaches to understanding the development of the nervous system. A variety of model organisms will be used to investigate neural induction, patterning, neural crest cell migration and axon guidance. Prerequisite: Biology 200 or consent of instructor.
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3.00 Credits
NA A.Morris A fundamental process in the development of the vertebrate nervous system is the partitioning of nervous system into distinct domains of cellular differentiation, for example the brain vs. the spinal cord. This seminar course will explore, through a series of student research article presentations, the molecular processes by which pattern is established in the nervous system and the morphological consequences of improper patterning. Human birth defects and pathologies such as spina bifida and brain tumors will be used as case studies to discuss the role of crucial patterning genes and signaling molecules. Enrollment limited to 15 students. Prerequisite: Biology 309 or consent of instructor.
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3.00 Credits
NA K.Johnson The world of the cell contains a rich array of molecular machinery that carries out life's dynamic processes. Interdisciplinary studies of these mechanisms employing a variety of biological, chemical and physical approaches are revealing a wealth of detail spanning from visible phenomenon to the scale of atoms and molecules. Extensive reading of the primary literature will be used as a basis for student-led discussions. Topics will be selected from a list including viral assembly, cellular clocks, mechanoenzyme engines, biosynthetic machinery and the assembly and regulation of cytoskeletal arrays. These systems provide novel insights into how work is accomplished (and regulated) in a nano-scale environment and serve as models for the development of microtechnologies for science and medicine. Enrollment limited to 15 students. Prerequisite: Biology 302 or consent of instructor.
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3.00 Credits
NA J.Owen Topics include description and classification of the cells and tissues of the immune system; cell collaboration in the immune response; transplantation antigens and their role in graft rejection and recognition of virally-infected cells; immune tolerance; lymphokines. There will be student presentations of articles in the original immunological literature, followed by critical discussion. Enrollment limited to 15 students. Prerequisite: Biology 300b, Biology 308 or consent of instructor.
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