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Course Criteria
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0.50 - 3.00 Credits
Detailed instruction in the use of a scanning electron microscope (SE M) and support techniques such as critical point drying, specimen coating (standard vacuum and sputter coating), specimen fixation, black and white photographic techniques and computer image acquisition and analysis. The theory and practice of energy dispersive x-ray analysis (EDAX) for determining atomic element makeup and element mapping will also be learned. Prerequisite: any 200- or 300-level science course or permission of the instructor. Counts toward the neuroscience major (cellular track). Also offered as Geology 391.
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0.50 Credits
(0.5 unit) Confocal microscopy allows a fluorescence-labeled specimen to be optically sectioned at magnifications up to 1000X. It is a good bridge between standard fluorescence microscopy and electron microscopy. This course offers students detailed instruction in the theoretical and practical aspects of using a laser scanning confocal microscope. Students learn specimen preparation techniques, fluorescent dye properties and selection, immuno-cytochemistry, laser physics, optics, and digital image acquisition and analysis. A good knowledge of cell biology and structure is very helpful. As a half-unit offering, the course meets for about half the semester. Prerequisites: any 200- or 300-level science course or permission of the instructor. Counts toward the neuroscience major (cellular track).
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0.50 - 3.00 Credits
This half-unit module is designed to allow students to develop and carry out a research project with the TEM, SEM/EDAX or Confocal microscope. This module may be taken concurrently with the corresponding half-unit microscopy modules but may be taken at a later time as well. Students should not take more than one unit total of the half-unit modules in this research methods series in one semester. As a half-unit offering, this project should be completed in about half the semester. Students are encouraged to develop their project in consultation with other science faculty with whom they are working on research. Meeting times are by arrangement. Pre/co-requisites: Biology 390, 391 or 392 or permission of the instructor.
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4.00 Credits
This course introduces basic laboratory techniques and skills that are common in fields related to biochemistry, and applying those techniques to a guided research project. Attention is paid to both theory and application. Students develop a methodology notebook and prepare lab reports for each exercise, and write up the project in the style of a journal article. All learning is done in the laboratories, which meet two afternoons per week, plus a half-hour recitation section by arrangement. Prerequisites: Chemistry 222 and any one of Biology 231, 245, 246, 250, 391 or Chemistry 309 (which can be taken as a co-requisite). Required for the biochemistry major and also carries credit toward the biology major/minor. Also offered as Biochemistry 394.
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4.00 Credits
Molecular techniques have revolutionized how biologists address problems in genetics, medicine, ecology, systematics, conservation and many other fields. Students obtain hands-on experience using basic and advanced molecular techniques, such as western blotting, nucleic acid (DNA and RNA) isolation and purification, DNA sequencing, gel electrophoresis and polymerase chain reaction (PCR), to study gene expression and genetic variability. The molecular techniques studied are the same used in laboratories worldwide. In addition to gaining practical experience in the laboratory, students learn about the theories behind each molecular protocol and study how biologists apply molecular techniques to answer fundamental biological questions. Prerequisites: Biology 245, 246, 250 or 394. Also offered as Biochemistry 395.
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4.00 Credits
A variety of topics are covered in depth depending on the interests of the students. The course begins with an overview of metabolism and its hormonal regulation. Other topics may include protein synthesis and targeting, molecular immunology, sensory systems and neurotransmission, hormone action, membrane transport, oncogenes and cancer, photosynthesis and advanced topics in metabolism. Topics of current interest may also be included. Through both written and oral presentation, students develop their abilities to use the scientific literature and communicate in science. Prerequisite: Chemistry 309 or permission of instructor. Counts toward the neuroscience major (cellular track). Also offered as Biochemistry 415 and Chemistry 415.
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1.00 Credits
Intended for senior tutorials, these are courses on topics not regularly offered in the curriculum. May be offered for .5 or 1 unit of credit and may include a laboratory. Prerequisites depend on course content and consent of instructor. Major credit restricted
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4.00 Credits
Participation in the review, revision, preparation and presentation of materials in the lecture and laboratory portions of the General Biology course; responsibility for presenting a seminar concerning a week/s core curriculum and for student evaluation. Biology 460, no credit, may be repeated. Biology 461 may be taken once for one-half unit of credit following one semester of 460. Major credit restricted.
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4.00 Credits
Intensive investigation by a group of students and faculty of advanced topics not regularly offered in the curriculum. Students are responsible for preparation and presentation of much of the course content. Prerequisite: permission of instructor. One unit may apply to the minimum requirements for the major; otherwise, major credit restricted.
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1.00 Credits
Mentored study and research that is not experimental in design yet requires the analysis of primary literature-based data and the integration of this with current knowledge of the subject matter. A thorough understanding of the methodologies used in acquiring the published data will be critical for this integration. This research will be presented orally to the mentor's research team and in appropriate written formats (e.g., journal manuscripts, etc.). This experience will typically earn 1 unit of credit toward the minimum major requirements and will be of at least one semester in duration. If not intending to accomplish honors designation, students may do a full year of research for .5 units per semester or they may elect to earn more than 1 unit of research credit, though only one such unit will count toward the minimum major requirement. Open to senior students majoring in biology. Prerequisite: sponsorship by a faculty member.
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