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Course Criteria
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0.00 - 4.00 Credits
Survey of the principles of the structure and properties of non-molecular solids. Space group symmetry, structure determination by x-ray, and neutron diffraction. Introduction to electron microscopy. Important structure types in metals and oxides. Pauling Rules, solid solutions, nonstoichiometry, and defect chemistry.
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0.00 - 4.00 Credits
A detailed review of recent successes and failures in the discovery of new drugs. Therapeutic areas to be discussed include: HIV, oncology, asthma, Alzheimer's Disease, antibiotics, diabetes, and neglected diseases (malaria, TB, human African Trypaonosomiasis). Case studies presented by leading pharmaceutical scientists will complement discussions of the functional steps required to select a target, indentify a new chemical entity, and get it to patients. The course will emphasize the integration of the molecular sciences and the role of chemistry in inventing and producing important new medicines.
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0.00 - 4.00 Credits
Discussion and evaluation of the role professional researchers play in dealing with the reporting of research, responsible authorship, human and animal studies, misconduct and fraud in science, intellectual property, and professional conduct in scientific relationships. Participants are expected to read the materials and cases prior to each meeting. Successful completion is based on regular attendance and active participation in discussion. This half-term course is designed to satisfy federal funding agencies' requirements for training in the ethical practice of scientists. Required for chemistry graduate students/post-docs.
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0.00 - 4.00 Credits
Course prepares graduate students with the basic skills in quantum mechanics for their independent research. Course begins wtih a review of basic concepts in quantum mechanics, then moves to symmetry and group theory, time-dependent formulism, occupation number presentation, light-matter interaction, quantum scattering theory, reaction rates, time-dependent approach to spectroscopy, correlation functions, and density matrix forumlism.
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0.00 - 4.00 Credits
Selected advanced topics in quantum mechanics including: time-dependent quantum mechanics, angular momentum theory, scattering theory, and radiation-matter interactions.
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0.00 - 4.00 Credits
Statistical mechanics provides the basis for understanding the equilibrium and nonequilibrium properties of matter in terms of the microscopic details of molecular interactions and structure. The course aims to provide students with working knowledge of the fundamentals and applications of statistical mechanics.
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0.00 - 4.00 Credits
A survey of atomic and molecular energy levels and the Hamiltonians that describe them. The interaction of radiation with matter, including multiphoton effects and nano-optics. Examples include electronic and nuclear spectroscopy of molecules and crystals, electron spin resonance, microwave spectroscopy, and the uses of lasers in modern spectroscopic research.
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0.00 - 4.00 Credits
Selected basic principles of molecular spectroscopy covered as a basis to discuss the manipulation of molecular quantum dynamics phenomena with tailored radiation pulses.
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0.00 - 4.00 Credits
A survey of chemical kinetics. Kinetic measurements and experimental methods, reaction rate theory, molecular dynamics experiment and theory will be discussed. Both gas phase and condensed phase kinetic studies will be considered.
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0.00 - 4.00 Credits
This course provides a comprehensive introduction to basic principles of macromolecular structure, stability, and interactions. Major topics include protein structure; protein thermodynamics and folding; nucleic acid structure and stability; principles of intermolecular recognition; and principles and practice of ligand binding analysis. Special emphasis is placed on understanding the relationships between structure and stability; the molecular origins of cooperative effects; and the relationships between covalent and non-covalent properties, in macromolecular systems.
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