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 Course Criteria
	
	
		
	
		
			
			
		
			
			
			
			
					
						
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								3.00 Credits 
								Introduction to reproductive and developmental toxicology that examines causes and manifestations both of structural malformations and of functional deficits in mammals. Topics covered include interactions between external factors and developmental gene expression, the behavioral consequences of chemical exposure, identification and regulation of reproductive and developmental toxicants. Examples emphasize reproductive and developmental toxicants that are present in the human environment. Same as ENVS 516. Prerequisite: Consent of instructor.
 
							
						
						
							
								 
									
								1.00 - 3.00 Credits 
								Same as ANSC 533 and MCB 533. See ANSC 533.
 
							
						
						
							
								 
									
								1.00 - 2.00 Credits 
								Provides veterinary professional students and graduate students with an introduction to the use of medical reasoning and technology in the investigation of problems related to conservation biology and ecosystem health. The course is an interactive, video conference assisted seminar series, jointly hosted by the University Of Illinois College Of Veterinary Medicine, Loyola University Chicago Stritch School of Medicine, and the Chicago Zoological Society/Brookfield Zoo. Together, these institutions comprise the "Conservation Medicine Center of Chicago." Topics include the evolutionary origins of HIV/AIDS, the ecology of vector- borne diseases, global amphibian population declines, wildlife epidemiology and pathology, and the role of zoos in disease surveillance and management. Approved for S/U grading only. Credit is not given for both CB 540 and PATH 640.
 
							
						
						
							
								 
									
								4.00 Credits 
								Gives participants the background information and hands-on experience in the methodologies necessary to utilize cloned genes for the detection and quantitation of specific mRNA transcripts in RNA extracted from tissue or cell culture samples. Methodologies covered will include: recombinant plasmid propagation, cDNA probe isolation and isotopic labeling, RNA isolation, Poly A+ mRNA selection, gel separation and transfer of RNA to a membrane (Northern blot), hybridization of specific gene probes to membrane bound RNA (Northern hybridization), detection and quantitation of hybridization signal. These basic methodologies are widely applicable to different experimental systems. They allow an investigator to monitor the effects of physiological manipulations, to animals or cultured cells, at the molecular level. Prerequisite: Consent of instructor.
 
							
						
						
							
								 
									
								2.00 Credits 
								Sources, environmental fate, and adverse effects of manmade and naturally-occurring chemicals on terrestrial and aquatic wildlife and ecological systems. Addresses wildlife health, including direct toxic effects and indirect effects via toxicity to other species. Focuses mainly on northern hemisphere with multiple examples from North America and Europe. Includes methods to reduce and prevent ecological and wildlife health problems. Includes one or more field trips comparing samples and animals from contaminated, pristine, and remediated sites. Examines laboratory ecotoxicology methods. Prerequisite: At least one semester of biology (IB 150 or equivalent), and biochemistry (MCB 354 or equivalent).
 
							
						
						
							
								 
									
								1.00 Credits 
								Ethical issues in the practice of toxicological research collaboration, authorship and plagiarism, professional responsibility to subjects (both human and animal), whistle-blowing, codes of ethics, legal obligations. Case Studies.
 
							
						
						
							
								 
									
								4.00 Credits 
								Introduction to principles and methods of detection and quantification of toxicants, drugs, metabolites and decomposition products in biological fluids, tissues, and environment matrices; emphasis on current laboratory methods and procedures (spectroscopy, chromatography, immunoassay, sample preparation, validation, and data interpretation).
 
							
						
						
							
								 
									
								3.00 Credits 
								Lecture-discussion of the clinical use in animals of human and veterinary drugs, including current literature review on pharmacodynamic species differences, novel indications, and contrast of therapeutic alternatives. Prerequisite: Graduate Veterinarian or consent of instructor.
 
							
						
						
							
								 
									
								1.00 Credits 
								Required of all graduate students whose major is veterinary biosciences.
 
							
						
						
							
								 
									
								0.00 - 1.00 Credits 
								Review and discussion of selected topics. Students are required to participate in weekly discussions and present one formal seminar per year, on a topic approved by the instructor. Approved for S/U grading. May be repeated to a maximum of 4 hours. Prerequisite: Enrollment in CB graduate program or consent of instructor.
 
							
						 
				
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