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Course Criteria
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3.00 Credits
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester.
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0.00 Credits
A seminar course in which selected topics in biomedical engineering are presented by students, faculty and guest investigators.
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3.00 Credits
Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of cell structure and function, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, methods for studying genes and gene expression at the mRNA and protein levels, methods for mutating genes and introducing genes into cells, methods for creating genetically-engineered mice and methods for accomplishing gene therapy by direct in vivo gene transfer.
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3.00 Credits
Develops an intuitive understanding of the mathematical systems theory needed to understand and design biomedical imaging systems, including ultrasound, magnetic resonance imaging and computed tomography. Topics will include multidimensional Fourier transform theory, image reconstruction techniques, diffraction theory, and Fourier optics.
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3.00 Credits
Studies engineering and physical principles underlying the major imaging modalities such as X-ray, ultrasound CT, MRI, and PET. A comprehensive overview of modern medical imaging modalities with regard to the physical basis of image acquisition and methods of image reconstruction. Students learn about the tradeoffs, which have been made in current implementations of these modalities. Considers both primarily structural modalities (magnetic-resonance imaging, electrical-impedance tomography, ultrasound, and computer tomography) and primarily functional modalities (nuclear medicine, single-photon-emission computed tomography, positron-emission tomography, magnetic-resonance spectroscopy, and magnetic-source imaging). Corequisite: BIOM 610 or instructor permission.
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3.00 Credits
Comprehensive overview of medical image analysis and visualization. Focuses on the processing and analysis of these images for the purpose of quantitation and visualization to increase the usefulness of modern medical image data. Topics covered involve image formation and perception, enhancement and artifact reduction, tissue and structure segmentation, classification and 3-D visualization techniques as well as pictures archiving, communication and storage systems. Involves ‘hands-on’ experience with homework programming assignments.
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3.00 Credits
Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of genetics, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, recombinant DNA methodology, methods for analyzing gene expression (including microarray and genechip analysis), methods for creating genetically-engineered mice, and methods for accomplishing gene therapy by direct in vivo gene transfer.
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3.00 Credits
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester.
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3.00 Credits
Underlying principles of array based ultrasound imaging. Physics and modeling techniques used in ultrasound transducers. Brief review of ID circuit transducer models. Use of Finite Element techniques in transducer design. Design considerations for 1.5D and 2D arrays will be reviewed. Diffraction and beamforming will be introduced starting from Huygen’s principle. FIELD propagation model will form an important part of the class. In depth discussion of various beamforming and imaging issues such as sidelobes, apodization, grating lobes, resolution, contrast, etc. The course addresses attenuation, time-gain-compensation and refraction. Finally, speckle statistics and K-Space techniques will be introduced. Laboratories will involve measuring ultrasound image metrics, examining the effect of various beamforming parameters and simulating these on a computer using Matlab.
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3.00 Credits
The course covers the physical principles of nuclear magnetic resonance, the biological and medical problems addressed using MRI, the analysis and design of MRI pulse sequences from a signal processing perspective, and MR image reconstruction techniques. It will introduce various advanced topics, such as cardiac MRI and spectroscopic imaging. The course will include laboratory sessions working with an MRI scanner. Prerequisites: BME 7782 Biomedical Imaging Systems Theory, or knowledge of 2D Fourier transforms and linear systems theory.
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