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Course Criteria
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3.00 Credits
A year-long design project in biomedical engineering required for BME majors. Students select, formulate, and solve a design problem either for a device or system ‘design & build’ project or a ‘design of experiment’ research project. Projects use conceptual design, skills obtained in the integrated lab, and substantial literature and patent reviews. Projects may be sponsored by BME faculty, medical doctors, and/or companies. Students may work on their own with outside team members when appropriate or with other SEAS students in integrative teams.
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3.00 Credits
Focuses on the study of forces (and their effects) that act on the musculoskeletal structures of the human body. Based on the foundations of functional anatomy and engineering mechanics (rigid body and deformable approaches); students are exposed to clinical problems in orthopedics and rehabilitation.
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3.00 Credits
Introduces transducers and instrumentation systems used in measuring biological variables. Discusses the physical, electromagnetic, and chemical principles of measurement, effects of interfaces between biological systems and sensors, and design tradeoffs. Surveys major electronic circuits and signal conditioning systems for biological and medical monitoring. Laboratory experiments involve construction and characterization of simple transducers, imaging systems, and signal conditioning equipment for biological variables, such as blood pressure, displacement, force, temperature, flow, and biopotentials. Exercises cover conceptual design to detailed design specifications for selected biomedical instrumentation systems.
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3.00 Credits
This course will provide an introduction to biomaterials science and biological interactions with materials, including an overview of biomaterials testing and characterization. The emphasis of this course, however, will be on emerging novel strategies and design considerations of biomaterials. Areas of concentration will include the use of polymers and ceramics in biomaterials today, drug delivery applications, tissue engineering from both an orthopaedic and vascular perspective, and nanotechnology related to biomaterials. Specific attention will also be paid to the in vitro and in vivo testing of biomaterials, and a review of current research in the field.
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3.00 Credits
Introduces the fundamental principles of tissue engineering. Topics include: tissue organization and dynamics, cell and tissue characterization, cell-matrix interactions, transport processes in engineered tissues, biomaterials and biological interfaces, stem cells and interacting cell fate processes, and tissue engineering methods. Examples of tissue engineering approaches for regeneration of cartilage, bone, ligament, tendons, skin and liver are presented.
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3.00 Credits
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester. Recent topics include Medical Imaging Systems Theory, BME Advanced Design, BME Electronics Lab, and Systems Biology Modeling and Experimentation.
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3.00 Credits
Studies the biophysical mechanisms governing production and transmission of bioelectric signals, measurement of these signals and their analysis in basic and clinical electrophysiology. Introduces the principles of design and operation of therapeutic medical devices used in the cardiovascular and nervous systems. Includes membrane potential, action potentials, channels and synaptic transmission, electrodes, electroencephalography, electromyography, electrocardiography, pacemakers, defibrillators, and neural assist devices.
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3.00 Credits
An overview of modern medical imaging modalities with regard to the physical basis of image acquisition and methods of image reconstruction. Topics cover the basic engineering and physical principles underlying the major medical imaging modalities: x-ray (plain film, mammography, and computed tomography (CT)), nuclear medicine (positron-emission tomography (PET) and single-photo-emission computed tomography (SPECT)), ultrasound, and magnetic resonance imaging (MRI). Taught concurrent with BIOM 783.
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4.00 Credits
Introduces the fundamental principles of medical image analysis and visualization. Focuses on the processing and analysis of ultrasound, MR, and X-ray images for the purpose of quantitation and visualization to increase the usefulness of modern medical image data. Includes image perception and enhancement, 2-D Fourier transform, spatial filters, segmentation, and pattern recognition. A weekly lab develops skill in computer image analysis with the KHOROS system.
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3.00 Credits
Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of cell structure and function, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, methods for studying genes and gene expression at the mRNA and protein levels, methods for mutating genes and introducing genes into cells, methods for creating genetically-engineered mice and methods for accomplishing gene therapy by direct in vivo gene transfer.
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