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Course Criteria
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3.00 Credits
Introduces the principles of continuum mechanics of biological tissues and systems. Topics include (1) review of selected results from statics and strength of materials, continuum mechanics, free-body diagrams, constitutive equations of biological materials, viscoelastic models, and fundamental concepts of fluid mechanics and mass transport; (2) properties of living tissue; (3) mechanical basis and effects of pathology and trauma, (4) introduction to mechanotransduction, circulatory transport, growth and remodeling, and tissue-engineered materials, and (5) low Reynolds number flows in vivo and in microsystems. (Y) Prerequisites & Notes Prerequisite: APMA 212, APMA 213, and BIOM 201, or instructor permission. Credits: 3
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3.00 Credits
Biotransport in biological living systems is a fundamental phenomenon important in all aspects of the life cycle.? Course will introduce principles and application of fluid and mass transport processes in cell, tissue and organ systems.? Topics include, introduction to physiological fluid mechanics in the circulation and tissue, fundamentals of mass transport in biological systems, effects of mass transport and biochemical interactions at the cell and tissue scales, and fluid and mass transport in organs. (Y) Prerequisites & Notes APMA 212, 213, BIOM 201, and BIOM 204 or equivalent, or instructor permission. Corequisite: BIOM 322, or instructor permission. Credits: 3
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3.00 Credits
An introductory course to neural networks research, specifically biologically-based networks that reproduce cognitive phenomena. The goal of this course is to teach the basic thinking and methodologies used in constructing and understanding neural-like networks.? Cross-listed as NESC 533. (Y) Prerequisites & Notes CS 101; and BIOM 201; or permission of the instructor. Credits: 3
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4.00 Credits
First half of a year-long course to integrate concepts and skills from prior courses in order to formulate and solve problems in biomedical systems, including experimental design, performance, and analysis. Lab modules include testing in tissues/cells and manipulation of molecular constituents of living systems to determine their structural and functional characteristics for design of therapeutic or measurement systems. Methods include biochemical, physiological, cell biology, mechanical, electrical and computer, systems, chemical, imaging, and other approaches. (Y) Prerequisites & Notes Prerequisite: APMA 212, APMA 213, APMA 311, BIOM 201, BIOM 204, and BIOM 322, or instructor permission; corequisite: BIOM 310 or instructor permission. Credits: 4
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4.00 Credits
Second half of a year-long course to integrate the concepts and skills from prior courses in order to formulate and solve problems in biomedical systems, including experimental design, performance, and analysis. Lab modules include testing in tissues/cells and manipulation of molecular constituents of living systems to determine their structural and functional characteristics and to design measurement or therapeutic systems. Methods include biochemical, physiological, cell biology, mechanical, electrical and computer, systems, chemical, imaging, and other approaches. (Y) Prerequisites & Notes Prerequisite: BIOM 380 or instructor permission. Credits: 4
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3.00 Credits
Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of cell structure and function, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, methods for studying genes and gene expression at the mRNA and protein levels, methods for mutating genes and introducing genes into cells, methods for creating genetically-engineered mice and methods for accomplishing gene therapy by direct in vivo gene transfer. (SI) Prerequisites & Notes Prerequisite: BIOM 201, 202, and 204 or CHE 246, and third- or fourth-year standing, or instructor permission. Credits: 3
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3.00 Credits
Introduces transducers and instrumentation systems used in measuring biological variables. Discusses the physical, electromagnetic, and chemical principles of measurement, effects of interfaces between biological systems and sensors, and design tradeoffs. Surveys major electronic circuits and signal conditioning systems for biological and medical monitoring. Laboratory experiments involve construction and characterization of simple transducers, imaging systems, and signal conditioning equipment for biological variables, such as blood pressure, displacement, force, temperature, flow, and biopotentials. Exercises cover conceptual design to detailed design specifications for selected biomedical instrumentation systems. (Y) Prerequisites & Notes Prerequisite: BIOM 310 or ECE 203, or instructor permission. Credits: 3
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3.00 Credits
This course will provide an introduction to biomaterials science and biological interactions with materials, including an overview of biomaterials testing and characterization.? The emphasis of this course, however, will be on emerging novel strategies and design considerations of biomaterials.? Areas of concentration will include the use of polymers and ceramics in biomaterials today, drug delivery applications, tissue engineering from both an orthopaedic and vascular perspective, and nanotechnology related to biomaterials.? Specific attention will also be paid to the in vitro and in vivo testing of biomaterials, and a review of current research in the field. (Y) Prerequisites & Notes Prerequisite: BIOM 201, BIOM 204 or equivalent, 3rd or 4th year standing, or instructor permission. Credits: 3
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3.00 Credits
Introduces the fundamental principles of tissue engineering.? Topics include: tissue organization and dynamics, cell and tissue characterization, cell-matrix interactions, transport processes in engineered tissues, biomaterials and biological interfaces, stem cells and interacting cell fate processes, and tissue engineering methods.? Examples of tissue engineering approaches for regeneration of cartilage, bone, ligament, tendons, skin and liver are presented. (Y) Prerequisites & Notes Prerequisite: APMA 213, BIOM 201, and BIOM 204 or equivalent, or instructor permission. Credits: 3
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3.00 Credits
Focuses on the study of forces (and their effects) that act on the musculoskeletal structures of the human body. Based on the foundations of functional anatomy and engineering mechanics (rigid body and deformable approaches); students are exposed to clinical problems in orthopedics and rehabilitation. (SI) Prerequisites & Notes Prerequisite: BIOM 201, 322, or instructor permission. Credits: 3
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