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Course Criteria
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0.00 Credits
May be repeated twice.
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3.00 - 12.00 Credits
Students will carry out a laboratory research project and related reference reading. Laboratory: 9-36 hours per week. May be repeated to a maximum of 12 credits. Prereq: Permission of instructor.
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3.00 Credits
Descriptive chemistry of amino acids and proteins, carbohydrates, lipids, and nucleic acids. Discussion of structure and function; metabolism and bioenergetics; and biological information flow. At the undergraduate level, understanding is demonstrated through hour examinations; at the graduate level, understanding is demonstrated through hour examinations and a brief paper. Lecture, three hours; one optional conference. Prereq: CHE 107, CHE 236 and BIO 152 or equivalent.
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4.00 Credits
A laboratory course dealing with the instrumentation and procedures of biochemical research. Because many of the materials used are labile, the course is given in a block during a four-week period at the end of the spring semester. Five days per week during four-week intersession, or summer session. Prereq: BCH 401G, 502 or 811 and consent of instructor.
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1.00 Credits
Each semester five distinguished scientists visit the UK campus to deliver a series of three formal lectures each and participate in numerous informal contacts with graduate students. The emphasis is on the presentation of the most current advances (often unpublished) in selected topics in molecular and cellular genetics. May be repeated to a maximum of six credits. (Same as BIO/MI/PLS/PPA 601.)
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3.00 Credits
An advanced course on the structure and function of proteins and nucleic acids. Topics include: the physical determinants of protein structure, classification of protein architecture, protein-nucleic acid and protein-protein interactions, sequence dependence of nucleic acid structure, ribozymes, dynamics and evolutionary relationships. Prereq: IBS 601-602/BCH 607-608 or equivalent.
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3.00 Credits
An introductory graduate-level biochemistry course designed to provide a basic knowledge of molecular and biochemical principles necessary for advanced graduate study. Protein structure and function, enzyme catalysis, the generation and storage of metabolic energy, amino acid, nucleotide, and lipid metabolism and biological membranes and transport will be covered. Prereq: CHE 105, 107, 230 and 232; BIO 150 and 152; or equivalents. (Same as IBS 601.)
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3.00 Credits
An introductory graduate-level biochemistry course focused on the cellular mechanisms that underlie the regulated expression of genes, including transcription and translation, as well as basic mechanisms of DNA replication/repair and recombination. Genetic engineering and other experimental approaches critical to molecular biology research will be reviewed. Prereq: CHE 105, 107, 230 and 232; BIO 150 and 152; or equivalents. (Same as IBS 602.)
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3.00 Credits
The course will consider the chemical constituents of plants (with emphasis on biologically or nutritionally significant compounds unique to plants), their biosynthesis, contribution to key metabolic and defense processes and the regulation of their synthesis. Included will be discussions of photosynthesis, carbohydrates, lipids, isoprenoids and phenylpropanoids, nitrogen fixation, nitrogen and sulfur reduction and assimilation, alkaloids and additional secondary compounds, frontiers in plant biochemistry. Prereq: BCH 607 or equivalent or consent of instructor. (Same as PLS/PPA 609.)
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3.00 Credits
A lecture and seminar course devoted to intermediary metabolism of lipids and various biochemical aspects of the structure, assembly and functions of biological membrane systems. Prereq: CHE 232, CHE 444G, BCH 401G, 502 or 811. BCH 502 may be taken concurrently.
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