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PHR 645: Neurotoxicology
2.00 Credits
University of Kentucky
Multidisciplinary discussions of the major sites and mechanisms of drug/chemical-induced nervous system toxicity. Presentations by faculty and graduate students. Prereq: BCH 501 and 502, PGY 502 and PHA 522 or equivalent and consent of instructor. (Same as TOX 645.)
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PHR 647: Introduction to Molecular Pharmacotherapeutics
3.00 Credits
University of Kentucky
A discussion of the development of potential therapeutic entities using molecular biotechnology. Recent advances in the design and delivery of target-specific treatments such as special peptides, monoclonal antibodies and gene therapies will be the primary focus. Prereq: BCH 501 and 502, BCH 401G or equivalent or consent of instructor.
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PHR 649: Advanced Molecular Pharmacology
2.00 Credits
University of Kentucky
This course will provide in-depth coverage of the molecular pharmacology of growth factors, transcription factors, receptors, and ion channels. Emphasis will be placed on both the normal functions of these cell-signaling molecules and perturbations that result in several prevalent human diseases, including cancer, Alzheimer's, diabetes, osteoporosis, and inherited human illnesses. Students will be introduced to experimental approaches to diagnosing and treating these illnesses in the light of our evolving knowledge of molecular pharmacology. Prereq: IBS 601-606 or consent of instructor. (Same as PHA/TOX 649.)
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PHR 665: Ethical Issues in Clinical Research
3.00 Credits
University of Kentucky
Based on NIH guidelines for Responsible Conduct of Research, this course will present ethical and regulatory guidelines for conducting clinical research. Prereq: Participation in curriculum leading to Graduate Certificate in Clinical Research Skills, or permission of instructor. (Same as CPH 665.)
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PHR 748: Master's Thesis Research
0.00 Credits
University of Kentucky
Half-time to full-time work on thesis. May be repeated to a maximum of six semesters. Prereq: All course work toward the degree must be completed.
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PHR 748 - Master's Thesis Research
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PHR 749: Dissertation Research
0.00 Credits
University of Kentucky
Half-time to full-time work on dissertation. May be repeated to a maximum of six semesters. Prereq: Registration for two full-time semesters of 769 residence credit following the successful completion of the qualifying exams.
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PHR 749 - Dissertation Research
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PHR 760: Topics in Pharmaceutical Sciences
1.00 - 4.00 Credits
University of Kentucky
This course deals with emerging concepts in pharmaceutical sciences which are not being covered in other courses. May be repeated to a maximum of 10 hours. Prereq: Consent of instructor.
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PHR 760 - Topics in Pharmaceutical Sciences
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PHR 762: Bioorganic Mechanisms
3.00 Credits
University of Kentucky
An in-depth discussion on the bioorganic chemistry aspects of the active sites of enzymes and drug receptors, the molecular basis of drug design, and principles of drug metabolism. Within these topics, the mode of action of some of the major coenzymes and drugs will be discussed from a mechanistic chemistry point of view. Prereq: CHE 538, CHE 633, BCH 501 or consent of instructor.
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PHR 764: Drug Development Regulation And Clinical Research
3.00 Credits
University of Kentucky
A study of the pharmaceutical development process and its regulation, including a detailed examination of clinical research methodologies. Students will demonstrate their competence by developing a clinical trial protocol. Prereq: Enrollment in the Pharmaceutical Sciences graduate program or consent of instructor.
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PHR 767: Dissertation Residency Credit
2.00 Credits
University of Kentucky
Residency credit for dissertation research after the qualifying examination. Students may register for this course in the semester of the qualifying examination. A minimum of two semesters are required as well as continuous enrollment (Fall and Spring) until the dissertation is completed and defended.
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