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Course Criteria
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2.00 Credits
Basic clinical laboratory principles and techniques; includes laboratory safety, sterilization procedures, pipetting, microscopy, routine culture and staining procedures, chamber counts, laboratory math calculations and statistics, quality control, quality assurance, chain of custody and laboratory reporting. Consent of instructor required for non-CSC students.
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4.00 Credits
A study of disease processes, pathognomonic parameters, and pathologic factors that mediate disease. Diagnostic testing used to validate disease process will be used to emphasize to the student the role of clinical sciences in the diagnosis of these complex disease states. Variances in disease in relationship to age will be examined. Prereq: Admission to the Clinical Sciences graduate program or consent of the course faculty committee.
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3.00 Credits
The focus of this integrative course will be on policy and ethical issues confronting health care providers, health care systems, and particularly those issues specific to clinical sciences. Emphasis will be placed on current trends and anticipated challenges in providing humane and cost-effective health care services, with particular reference to the medically underserved and other at-risk populations. The different needs of special populations such as the aging, socioeconomically disadvantaged, insured and underinsured persons, ethically and culturally diverse groups such as recent immigrants and minorities will be explored. Discussion of technology dissemination delivery models, funding sources, human resources required to provide health care, alternative methods of coordinating these resources, and shifting from an "illness" orientation to a "wellness" approach will be included. The bioethics of health care delivery addressed will also include global considerations relative to health care, population dynamics, health care rationing, health care economics and assisted reproduction and transplantation issues.
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1.00 Credits
Provides skills required of successful scientist to communicate effectively with peers, clients and general public. Each student will demonstrate an ability to interact with community, to function in an educator role by investigating a topic and preparing and delivering a presentation to the class and a community group. May be repeated up to five times. Prereq: Admission to the Clinical Sciences graduate program or consent of instructor.
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4.00 Credits
Accreditation processes are evaluated with special emphasis on standards established by agencies and organizations such as JCAHO, CAP, FDA, NCCLS (FCC). The continuing quality control demands of the Clinical Laboratory Improvement Act of 1988 (CLIA '88) and the various accrediting bodies are addressed through a statistical approach that examines descriptive and inferential analysis to include hypothesis testing (t-test), power and confidence intervals, OVA-testing and regression analysis, TEA algorithms, reference range establishment, interference studies, bias studies, method comparison, validation studies, and, unstable error studies. Performance and utilization management systems, standard compliance issued related to Medicare laboratory fee schedules, CPT and ICD coding, reimbursement strategies and other billing practices are presented. The course concludes with a unit on OSHA that delineates chemical and infectious hazards and safety in the laboratory. Prereq: Admission to the Clinical Sciences graduate program or consent of the course faculty committee.
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3.00 Credits
Introduction to experimental design, data collection and data analyses for clinical biomedical research. Students will also examine ethical issues in biomedical science research using a case-study approach. Representative issues to be addressed may include data selection and retention, plagiarism, scientific review of grants and manuscripts, review of protocols by human studies committees (institutional review boards or IRB) and informed consent.
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3.00 Credits
This course will provide a foundation in the principles and methods of the epidemiological investigation of disease with special emphasis on the distribution and dynamic behavior of disease in a population. Etiologic factors, modes of transmission and pathogenesis will be examined. Topics to be covered include epidemics and the spread of infectious disease, epidemiological aspects of non-infectious disease; rates of morbidity and mortality; sensitivity, specificity, and predictive values; strategies used in epidemiological studies to include measures of disease effect, validity, reliability, sampling methods and computer-based biostatistical analysis that emphasize the generalized linear model and forms of SEM.
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3.00 Credits
Applications-based statistical and analytical software is used to demonstrate Continuing Quality Improvement (CQI) adherence to Federal regulation, NCCLS/IFCC protocols, and other accrediting agency requirements. Special emphasis is on defining and controlling unstable error through a statistical modeling approach. Documentation structures for quality operations policy; and processes, procedures and implementation of a quality system are examined with special attention to assuring quality of point-of-care testing. Detailed computerized study of method comparison includes receiver operator charting (ROC). Computerized diagnostic screening programs are used to evaluate prevalence, sensitivity, specificity, and predictive values. Utilization of management systems to track expenses, budget/inventory management, employee scheduling, productivity evaluations, process improvement and restructuring are demonstrated. Computerized performance management systems and innovations in compliance strategies are featured. Student evaluation will be based on examinations, projects, and papers.
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3.00 Credits
Review of the male reproductive system including hormonal control, early development, spermatogenesis and fertilization. Basic and advanced andrology procedures will be discussed and laboratories will focus on semen analysis, sperm function tests, and preparation of partner and donor semen for artificial insemination. Prereq: BIO 549.
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3.00 Credits
Review of female reproductive system including hormonal control, early development, oogenesis, the menstrual cycle, fertilization and early implantation. Assisted reproductive technology procedures will be discussed with the aid of photographs and videos and laboratories will focus on culturing and manipulating mouse embryos. Prereq: BIO 549, CSC 620.
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