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Course Criteria
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3.00 Credits
No course description available.
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0.00 Credits
No course description available.
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0.00 Credits
No course description available.
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0.00 Credits
No course description available.
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0.00 Credits
No course description available.
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5.00 Credits
1001 GRADUATE BIOCHEMISTRY
COURSE LEADER: Dr. Anne Bresnick
CREDITS/CLASS MEETINGS: 5 semester hours, 4 sixty-minute classes per week, 58 lectures, 4 review sessions.
PREREQUISITE BACKGROUND: One semester of undergraduate biochemistry and a course in organic chemistry are required. Undergraduate physical chemistry is also helpful preparation. Students who are uncertain about the adequacy of their undergraduate training for this course should discuss the issue with their advisory committee and then consult the course leader.
TEXTBOOK FOR BACKGROUND READING AND REFERENCE: Biochemistry Third Edition, D. Voet and J. G. Voet
SUITABILITY FOR 1ST YEAR STUDENTS: First year graduate and MSTP students may enroll if their advisory committees judge their preparation in chemistry and biochemistry adequate.
COURSE DESCRIPTION: This is a one-semester introduction to fundamental topics in biochemistry and physical biochemistry, excluding most of metabolism (which is presented as a separate course during the spring semester). Topics included are: protein structure, folding, and function, nucleic acid structure and protein-DNA interactions, carbohydrates & glycoproteins, lipids & membranes, enzymology, energetics & allostery, posttranslational modification of protein function, transcription, translation, and DNA replication. Most of the material is presented in formal lectures in conjunction with sample problem sets, reading of the literature and discussion sessions.
Each student is required to take four non-cumulative examinations that cover each part of the course. One half of the first examination is a protein structure project. The project and examinations will be evaluated with feedback on student performance, but will not be graded. Students that complete the project, all four examinations and assigned problem sets or quizzes will receive a grade of Pass (P). Students who do not complete all of these assignments and do not have the approval of the course leader (granted in accord with the Academic Policies and Guidelines of the Graduate Division) will receive a grade of Fail (F).
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3.00 Credits
1002 BIOCHEMISTRY OF METABOLIC REGULATION
COURSE LEADERS:
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3.00 Credits
1003 BIOPHYSICAL CHEMISTRY OF MACROMOLECULES
COURSE LEADERS: Drs. Denis Rousseau and Syun-Ru Yeh
CREDITS/CLASS MEETINGS: 3 semester hours; 27 lectures. The class will meet two times per week for 1.5 hour lectures. The course will have two exams during the term and one final exam as well as homework assignments.
PREREQUISITE BACKGROUND: Open to all students - The course will dovetail with Graduate Biochemistry, building on concepts introduced in that class. Thus, concurrent or prior enrollment in Graduate Biochemistry (or its equivalent) is required. In general, students are recommended to have some background in Physical Chemistry and Biochemistry.
SUGGESTED BACKGOUND READING: Proteins by T.E. Creighton, Selected readings from Biophysical Chemistry by Cantor and Schimmel, Selected readings from Introduction to Protein Science by A. M. Lesk. Selected readings from the primary literature.
SUITABILITY FOR 1ST YEAR STUDENTS: Recommended to have some background in Physical Chemistry and Biochemistry.
COURSE DESCRIPTION: TThis course is Part 1 of an introductory graduate level course in biophysical chemistry offered every fall semester. Part 2 will be offered in the Spring Semester. The topics will focus on the structures and properties of proteins and nuclear acids, techniques used to study macromolecules and mechanisms of macromolecular function.
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0.00 - 4.00 Credits
1004 MOLECULAR CELL BIOLOGY
COURSE LEADERS:
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4.00 Credits
1005 MOLECULAR GENETICS
COURSE LEADER: Dr. Nicholas Baker
CREDITS/CLASS MEETINGS: 4 semester hours; corresponding to approximately 40 lectures.
PREREQUISITE BACKGROUND: 1 or more undergraduate Biology courses that include Mendelian genetics, molecular biology and microbiology. Students are expected to have a basic understanding of Mendelian genetics from their prior courses. Students lacking this background should arrange to study basic undergraduate genetics independently, with a tutor, or at another institution prior to enrolling.
SUGGESTED BACKGOUND READING: Griffiths et al., "An Introduction to Genetic Analysis". Hartwell et al. "Genetics: From Genes to Genomes". Watson et al., "Molecular Biology of the Gene"
SUITABILITY FOR 1ST YEAR STUDENTS: This course is designed primarily for first-year students, and serves as a foundation for several other graduate courses. Students who don't have the required background should consult with the course leader and their advisory committee.
COURSE DESCRIPTION: The field of Molecular Genetics now pervades all areas of modern biology. The purpose of this course is to provide a grounding in the principles and techniques of Molecular Genetics for students in all areas of research, including cell biology, developmental biology, protein structure and function, evolution, neuroscience, pharmacology and human disease. Molecular Genetics focuses upon the gene and understanding gene function through the creation or isolation of mutations.
The major goals of this course are to convey:
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