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CHEM 6210: Advanced Organic Chemistry I
3.00 Credits
Roberts Wesleyan University
An introduction to the organic chemical literature. A consideration of reactions of synthetic importance to the organic chemist with emphasis on the influence of structure on the behavior of organic molecules. When Offered: A fall-spring sequence annually. Credit Hours: 3
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CHEM 6210 - Advanced Organic Chemistry I
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CHEM 6220: Advanced Organic Chemistry II
3.00 Credits
Roberts Wesleyan University
An introduction to the organic chemical literature. A consideration of reactions of synthetic importance to the organic chemist with emphasis on the influence of structure on the behavior of organic molecules. When Offered: A fall-spring sequence annually. Credit Hours: 3
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CHEM 6220 - Advanced Organic Chemistry II
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CHEM 6280: Natural Products Chemistry
3.00 Credits
Roberts Wesleyan University
A survey of modern synthetic methods used in construction of the major groups of secondary metabolites and related natural products. The essentials of retrosynthetic analysis are presented and instruction in the development of strategies for organic synthesis are offered. Prerequisites/Corequisites: Prerequisites: CHEM 6210 and CHEM 6220. When Offered: Fall term odd-numbered years. Credit Hours: 3
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CHEM 6280 - Natural Products Chemistry
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CHEM 6300: Medicinal Chemistry
3.00 Credits
Roberts Wesleyan University
The organic chemistry of drug discovery and synthesis will be the focus of this course. Starting with the basic concepts of molecular-targeted drug discovery, the process of lead identification will be explored with special emphasis on drug screening and combinatorial chemistry. The roles of computational chemistry, molecular modeling, and biophysical methods in the understanding of the relationship between structure and biological activity will be studied. The chirality of drugs from both the biological and synthetic perspectives will also be explored. Prerequisites/Corequisites: Prerequisite: CHEM 6210 or permission of instructor. Credit Hours: 3
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CHEM 6300 - Medicinal Chemistry
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CHEM 6310: Bioorganic Mechanisms
3.00 Credits
Roberts Wesleyan University
The study of mechanisms of organic reactions in biochemical processes on a molecular level. Enzyme active sites, mechanisms of enzymatic transformations, catalysis, cofactors, enzyme kinetics, environmental toxicology. Strong emphasis on the design and mechanism of action of pharmaceutical agents. Meets with CHEM 4310; both courses cannot be taken for credit. Prerequisites/Corequisites: Prerequisite: permission of instructor. When Offered: Spring term odd-numbered years. Credit Hours: 3
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CHEM 6310 - Bioorganic Mechanisms
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CHEM 6330: Drug Discovery
3.00 Credits
Roberts Wesleyan University
This course will examine how bioinformatics, functional genomics and other modern biotechnologies are used to speed the discovery of new drugs, especially those small organic molecules to treat human diseases with large unmet therapeutic need. Special emphasis will be placed on molecular target identification and validation as well as high-throughput screening to identify a lead. Topics to be discussed will include transgenic mice, RNA interference, DNA and protein microarrays, homogenous time-resolved fluorescence bioassays, phage-display, combinatorial chemistry and parallel synthesis. Students cannot receive credit for both this course and CHEM 4330. Prerequisites/Corequisites: Prerequisite: A knowledge of organic chemistry is required. Credit Hours: 3
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CHEM 6330 - Drug Discovery
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CHEM 6450: Nonlinear Laser Spectroscopy
3.00 Credits
Roberts Wesleyan University
An introduction to the theory and practice of multiphoton or nonlinear laser spectroscopic and nonlinear optical phenomena. Emphasis is placed on the spectroscopic applications of nonlinear optical phenomena such as harmonic generation, sum and difference frequency generation, stimulated Raman scattering, multiphoton absorption and ionization, and four-wave mixing methods such as coherent anti-Stokes Raman scattering. There are no prerequisites, but a background in molecular spectroscopy is recommended. When Offered: Spring term odd-numbered years. Credit Hours: 3
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CHEM 6450 - Nonlinear Laser Spectroscopy
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CHEM 6480: Chemical Kinetics
3.00 Credits
Roberts Wesleyan University
Kinetics of thermochemical and photochemical reactions. Mathematical and mechanistic descriptions of the phenomenological approach to rate process; theoretical treatments of kinetically simple reactions; principles of light absorption and photochemistry; organic photochemistry. Prerequisites/Corequisites: Prerequisite: permission When Offered: of instructor. Spring term odd-numbered years. Credit Hours: 3
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CHEM 6480 - Chemical Kinetics
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CHEM 6490: Chemical Thermodynamics
3.00 Credits
Roberts Wesleyan University
The principles of thermodynamics, with their applications to homogeneous and heterogeneous equilibria. Prerequisites/Corequisites: Prerequisite: permission of instructor. When Offered: Offered on sufficient demand. Credit Hours: 3
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CHEM 6490 - Chemical Thermodynamics
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CHEM 6510: Computational Chemistry
3.00 Credits
Roberts Wesleyan University
This course is designed to cover the history and application of modern computational chemistry techniques to chemical problems. It will provide familiarity with the various methods and tools presently in use and the assumptions and limitations inherent in each approach. The format involves both lecture and studio modes of instruction and meets in a classroom where each student has a modern workstation. When Offered: Spring term even-numbered years. Credit Hours: 3
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CHEM 6510 - Computational Chemistry
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