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Course Criteria
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4.00 Credits
4 credits Supervised projects carried out in hospital, community or industrial settings. Evaluated on basis of written and oral reports presented to faculty and outside project co-sponsors. Faculty conferences and visits required. Open to senior students on approval of departmental adviser. Pre-planned experiences provide students with significant exposure to relationships between theoretical information and practical applications. Prerequisite: senior status or adviser's approval.
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3.00 Credits
The course offers an in-depth look at the role of biotechnology in the modern drug development process from the early stage of target identification and generation of lead compounds to the modern methods of drug delivery. All the key aspects, including pre-clinical development, clinical trials and regulatory requirements, will be covered in some detail with considerable input by the pharmaceutical industry professionals. Major classes of biotech drugs (e.g., antibodies and other biologics, antibiotics), will be discussed in some detail and real-life case studies will be presented to illustrate critical points in the overall development process. Prerequisite: Adviser's approval.
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3.00 Credits
This course focuses on the contribution of biotechnology to the modern Health Care. It provides a broad overview of the most exciting new technologies, such as tissue engineering and stem cell research, and discusses a wide range of applications. The course also offers an overview of more traditional biotech products e.g., vaccination, blood preservation and substitutes, diagnostics and discusses in some detail the role of biotechnology in the management of the biggest heath care challenges of our time, the aging population and obesity epidemics. Some key lecturers in the course will be delivered by leading industry professionals Prerequisite: Adviser's approval.
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3.00 Credits
The course primarily focuses on the commercial use of biological catalysts across various industry segments, including pharmaceuticals, health care, fine chemicals and food. The course combines a broad overview of the cutting-edge technologies with industrial insights into the economics of bio-processing, and deals with newly emerging trends in biomaterials. Case studies will be presented to facilitate the analysis, formulate the trends and underline major challenges. Prerequisite: Adviser's approval.
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3.00 Credits
Discussion of various biosensors, which consist of bio-recognition systems, typically enzymes or binding proteins such as antibodies, immobilized onto the surface of physico-chemical transducers. Immuno-sensors, which use antibodies as their bio-recognition system, are also discussed. Other biorecognition systems discussed are nucleic acids, bacteria, and whole tissues of higher organisms. Specific interactions between the target analyte and the complementary biorecognition layer that undergoes a physicochemical change is ultimately detected and measured by the transducer. Various transducers, which can take many forms depending upon the parameters being measured electrochemical, optical, mass and thermal changes are also part of the course. Prerequisite: Adviser's approval.
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3.00 Credits
Special Topics in Biotechnology. Prerequisite: Adviser's approval.
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3.00 Credits
Special project (experimental, theoretical, computational, or literature search). Prerequisite: adviser's approval
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3.00 Credits
Special project (experimental, theoretical, computational, or literature search). Prerequisite: adviser's approval
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3.00 Credits
Provides students with a working knowledge of how to use biotransformations as a tool in organic chemistry. Students will learn about general enzymatic reaction types that carry out the cleavage and formation of C-O bonds, P-O bonds, C-N bonds, C-C bonds, reduction reactions, oxidation reactions and isomerizations. In addition, students will be taught about advanced principles that are currently being applied to the engineering of catalytic proteins. Prerequisite: Adviser's approval.
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3.00 Credits
This course will introduce students to the modern protein engineering techniques available to researchers to understand protein structure and function and to create entirely new proteins for a variety of purposes. This is a new field that lies on the interface of chemistry, biology and engineering. The first part of the course will discuss the protein composition and structure, various genetic, biochemical and chemical techniques required to engineer proteins, which then will be followed by specific topics. Topics will include designing proteins that are highly structured; active at high temperatures and in non-aqueous solvents; that selectively interact with other proteins, small molecules and nucleic acids for therapeutic purposes; and that catalyze new reactions. Prerequisite: CM9413 or adviser's approval.
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