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  • EN 540.306: Chem & Bio Separation

    3.00 Credits
    Johns Hopkins University

    Prereq: 540.303, 540.202 This course covers staged and continuous-contacting separations processes critical to the chemical and biochemical industries. Separations technologies studied include distillation, liquid-liquid extraction, gas absorption, membrane ultrafiltration, reverse osmosis, dialysis, adsorption, and chromatography. Particular emphasis is placed on the biochemical uses of these processes and consequently on how the treatment of these processes differs from the more traditional approach.
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  • EN 540.313: Chemical and Biomolecular Engineering Lab

    6.00 Credits
    Johns Hopkins University

    Students will have additional meeting times outside of class. Students are challenged with laboratory projects that are not well-defined and learn to develop an effective framework for approaching experimental work by identifying the important operating variables, deciding how best to obtain them, and using measured or calculated values of these operating variables to predict, carryout, analyze and improve upon experiments. Each student analyzes various biomolecular engineering projects. In addition to technical objectives, this course stresses oral and written communication skills and the ability to work effectively in groups. * Prerequisites: 540.301, 540.304, 540.306, 540.490
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  • EN 540.314: Chem Eng Product/Process Design

    4.00 Credits
    Johns Hopkins University

    Prereqs: 540.311 or 540.313, 540.301 and 540.306 This course guides the student through the contrasting aspects of product design and of process design. Product design concerns the recognition of customer needs, the creation of suitable specifications, and the selection of best products to fulfill the needs. Process design concerns the quantitative description of processes, which serve to produce many commodity chemicals, the estimation of process profitability, and the potential for profitability improvement through incremental changes in the process. Students work in small teams to complete a major project demonstrating their understanding of and proficiency in the primary objectives of the course. Students report several times both orally and in writing on their accomplishments.
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  • EN 540.437: Application of Molecular Evolution to Biotechnology

    3.00 Credits
    Johns Hopkins University

    Prereqs: 020.305 or 580.221 One of the most promising strategies for successfully designing complex biomolecular fuinctions is to exploit nature's principles of evolution. This course provides an overview of the basics of molecular evolution as well as its experimental implementation. Current research problems in evolution-based biomolecular engineering will be used to illustrate principles in the design of biomolecules (i.e. protein engineering, RNA/DNA engineering), genetic circuits and complex biological systems including cells. (Will meet with EN.540.637)
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  • EN 540.475: Macromolecules at Interface

    3.00 Credits
    Johns Hopkins University

    By instructor's permission. This course involves integrated lecture/discussion and laboratory components to review and participate in current and emerging topics involving macromolecules at interfaces. Lectures and discussions review how fundamentals of macromolecular and interfacial science are connected to emerging problems in nano- and bio- technologies. Authentic inquiry activities in the laboratory are connected to diverse scientific and technological fundamental topics. Research and journal article presentations provide a context for laboratory activities with respect to current topics in a number of emerging research applications involving colloidal particles. Research design and strategy is discussed as a process distinct from existing elective course activities and guided inquiry activities in standard undergraduate laboratory courses. Applications include (but are not limited to) photonic crystals, reconfigurable antennas, drug delivery, biomolecular interactions, nanoparticles in the environment, and tissue engineering.
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  • EN 540.478: Current Aspects of Transport and Interfacial Phenomena Part 2

    3.00 Credits
    Johns Hopkins University

    By instructor's permission. This course involves integrated lecture/discussion and laboratory components to review and participate in current and emerging topics involving fluid mechanics and interfacial science. The lectures and discussions review how fundamentals of transport and interfacial science are connected to emerging problems in micro- and nanotechnologies. The mandatory laboratory component is aimed at connecting the topics covered in the class to scientific problems. Student participation will involve presentation of laboratory results and research papers.
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  • EN 540.479: Current Topics in Eukaryotic Cell Biotechnology

    3.00 Credits
    Johns Hopkins University

    This course involves integrated lecture/discussion and laboratory components to review and participate in current and emerging topics involving eukaryotic biotechnology. Lectures and discussions review how fundamentals of biochemical kinetics and biomolecular engineering are connected to emerging problems in mammalian, algal, and stem cell biotechnology. Laboratory activities are connected to diverse scientific and technological fundamental topics on these same themes. Journal article and research presentations provide a context for laboratory activities with respect to emerging industrial applications for eukaryotic cell types. Research design and strategy is discussed in terms of its ultimate implementation in laboratory, pilot plant, and eventually manufacturing facilities. Methodologies implemented include cell and metabolic engineering for improving yields and production rates of proteins, cells, and tissues. Example topics include expansion of mammalian, stem cells, and algae for the production of membrane proteins, biologics, biofuels, and complex metabolites.
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  • EN 550.103: Mathematics & Politics

    4.00 Credits
    Johns Hopkins University

    Examining interesting problems from the world of politics including apportionment, resource allocation, voting, and conflict, this course is designed for humanities and social science students who enjoy solving logic puzzles.
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  • EN 550.111: Statistical Analysis I

    4.00 Credits
    Johns Hopkins University

    Prerequisite: four years of high school mathematics. Students who may wish to undertake more than two semesters of probability and statistics should consider 550.420-430. First semester of a general survey of statistical methodology. Topics include descriptive statistics, probability models, random variables, expectation, sampling, the central limit theorem, classical and robust estimation of location, confidence intervals, hypothesis testing, two-sample problems, introductory analysis of variance, introductory nonparametric methods. Three lectures and a conference weekly. Some use of computing with the Minitab statistical package, but prior computing experience not required. Students can use any edition of the textbook.
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  • EN 550.112: Statistical Analysis II

    4.00 Credits
    Johns Hopkins University

    Prereq: 550.111 Second semester of a general survey of statistical methodology. Topics include least squares and regression analysis, correlation, further nonparametric methods, chi-square tests, the likelihood concept, decision theory, Bayesian inference, time series, simultaneous equations, sample survey design. Students who may wish to undertake more than two semesters of probability and statistics should consider 550.420-430.
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