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  • BIOL 1290: Cancer Biology

    1.00 Credits
    Brown University

    Provides a conceptual understanding of molecular events underlying development of human cancer. Focused on genetic changes leading to malignant transformation of cells. Covers cell cycle control, DNA damage, mutagenesis, cancer predisposition syndromes, oncogenic viruses, tumor immunology, metastasis, cancer chemotherapy and drug resistance. Lecture plus discussion of primary literature. Expected: Genetics and Cell Biology.
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  • BIOL 1310: Analysis of Development

    0.00 - 1.00 Credits
    Brown University

    Explores mechanisms underlying development. Topics: gamete interactions, establishment of body plans, cell signaling and tissue interactions, morphogenetic pattern formation, developmental regulation of gene expression, molecular control of tissue specification and diversification, and the evolutionary comparison of developmental processes. Primary literature will be discussed in sections. Laboratory, involves work with live embryos. Expected: BIOL 0200 (or equivalent), and one additional course in the area of genetics, embryology, cell biology, molecular biology. Graduate students register for BIOL 2310. Students MUST register for the lecture section and the lab. Expected: BIOL 0200; plus at least one of the following: BIOL 0280, 0310, 0320, 0470, 0500, 1050. Enrollment limited to 36. Instructor permission required.
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  • BIOL 1410: Evolutionary Genetics

    0.00 - 1.00 Credits
    Brown University

    This course will focus on selected topics in molecular population genetics, molecular evolution, and comparative genomics. Classic and current primary literature at the interface of evolution and genetics will be discussed in a seminar format. The laboratory involves wet-lab exercises (allozymes, PCR- RFLP, sequencing), plus computer labs using DNA analysis packages. Students will prepare a final grant proposal on specific research interests. Expected: BIOL 0470 or 0480. Students MUST register for the lecture section and the lab. Enrollment limited to 20. Instructor's permission required.
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  • BIOL 1420: Experimental Design in Ecology

    1.00 Credits
    Brown University

    An overview and discussion of the basic principles used to design lab and field experiments in ecology and environmental science. Topics include: replication and statistical power, appropriate use of factorial designs, nonparametric methods, post hoc texts, natural versus manipulative experiments, experimental artifacts and impact study design. Discussions based on primary literature and a new text. Expected: BIOL 0420.
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  • BIOL 1430: The Computational Theory of Molecular Evolution

    1.00 Credits
    Brown University

    This course employs intellectual traditions from computer science and biology to investigate the properties and principles of DNA sequence evolution. The roles of mutation, natural selection, population size and subdivision, and genetic recombination are explored. Lectures complemented by web-based computer exercises. Expected: either an introduction to evolution (BIOL 0200, 0480) or to computer science (CSCI 0150, 0160, 0170).
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  • BIOL 1440: Marine Biology

    1.00 Credits
    Brown University

    An examination of current topics in the ecology of marine organisms and communities. Current literature and ideas are analyzed in a seminar format (5hr/week). A class research project provides hands-on experience with designing and interpreting experimental field work. Prerequisites: BIOL 0410 and 0420. Instructor's permission required.
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  • BIOL 1460: Microbial Diversity and the Environment

    1.00 Credits
    Brown University

    This is a lecture and discussion based course that focuses on the role of microbes in ecological, geological, and environmental processes. This includes: introductory concepts, origins of life, role in climate change, functional diversity of biogeochemical cycles, microbial communities and interactions, habitat specific examples, and applications in the environment and human health. Expected: BIOL 0200, CHEM 0330 and an intermediate science course (e.g., BIOL 0280, GEOL 0240, or ENVS 0490).
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  • BIOL 1470: Conservation Biology

    1.00 Credits
    Brown University

    Conservation Biology is the scientific study of the phenomena that affect the maintenance, loss, and restoration of biological diversity. Topics covered include: 1) the impacts of global warming, species invasions, and habitat destruction on biodiversity, 2) strategies developed to combat these threats, and 3) a consideration of key economic and ethical tradeoffs. Special attention will be paid to current debate and controversy within this rapidly emerging field of study. Readings will include the primary literature. A term-paper will be required. Prerequisite: BIOL 0420 or instructor permission. Enrollment limited to 30.
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  • BIOL 1475: Biogeography

    1.00 Credits
    Brown University

    Will provide an overview of the field of biogeography--the study of geography of living organisms. Class meetings will be split between lectures and discussions. Each discussion will expose students to foundational papers, which set the context for the field's development, and more recent papers, which show where the field is headed. Each student will conduct a short (but time consuming) original research project on some topic in biogeography. A mandatory weekend-long field trip is required. Prerequisites: BIOL 0420 and 0480. Expected: one taxonomy-based course (e.g., BIOL 0410, 0430, or 0460). Enrollment limited to 15 juniors, seniors, and graduate students. Instructor permission required.
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  • BIOL 1480: Terrestrial Biogeochemistry and the Functioning of Ecosystems

    1.00 Credits
    Brown University

    Three fundamental multidisciplinary questions will be addressed: How do ecosystems work? What limits the growth of life on Earth? How are humans altering the framework in which all life exists? Earth is basically a closed chemical system, and the reactions that support life are fueled by sunlight. But added to this chemistry and physics is the tremendous influence of life. Life created an oxygen atmosphere; the evolution of biological nitrogen fixation exponentially increased how many organisms could exist, and the soils that support human food production developed only by biologically-mediated processes. Throughout Earth's 4.5 billion-year history changes in Earth's basic biogeochemical processes have been fairly slow. Under our inattentive stewardship, we have almost instantaneously altered all of the major element cycles. We will focus heavily on what these changes mean for life on Earth. Instructor permission required.
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