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BIOL 1120: Biomaterials
1.00 Credits
Brown University
A biomaterial is defined as a material suitable for use in medical implants that come in direct contact with patients' tissues. These include polymers, metals, and ceramics, and materials obtained from biological sources or through recombinant biotechnology. Goal: to provide comprehensive coverage of biomaterial science and technology. Emphasizes the transition from replacement to repair strategies. For advanced undergraduates and graduate students. Prerequisite: BIOL 0200, plus BIOL 0800 or 0280, or instructor permission.
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BIOL 1140: Tissue Engineering
1.00 Credits
Brown University
Tissue engineering is an interdisciplinary field that incorporates progress in cellular and molecular biology, materials science, and engineering, to advance the goal of replacing or regenerating compromised tissue function. Using an integrative approach, we will examine tissue design and development, manipulation of the tissue microenvironment, and current strategies for functional reconstruction of injured tissues. Expected: CHEM 0330, plus BIOL 0500 or 0800. Enrollment limited to 20. Instructor permission required.
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BIOL 1160: Principles of Exercise Physiology
1.00 Credits
Brown University
Application of the basic principles of physiology to the study of the response mechanisms of the human body during exercise. Topics include muscle and neural control, metabolism, energy sources, cardiovascular and respiratory effects, thermoregulation, and special topics (e.g., exercising at high altitude). Student presentations based on scientific articles are included. Expected: BIOL 0800 or written permission of the instructor.
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BIOL 1180: Comparative Animal Physiology
1.00 Credits
Brown University
Comparative approach to the function and regulation of animal systems with an emphasis on vertebrates. Topics include circulation, gas exchange, neuromuscular function, excretion, acid-base and ion regulation, and temperature regulation. Considers the unity and diversity of physiological processes in animals differing both in phylogeny and environmental adaptation. Original papers are discussed. Expected: BIOL 0800 or equivalent.
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BIOL 1190: Synaptic Transmission and Plasticity
1.00 Credits
Brown University
Synapses are the means by which the nervous system communicates. In this seminar-style course, we will explore the molecular and physiological underpinnings of synaptic transmission. We will then examine ways in which synapses can modulate their strength during development, learning, and other adaptive processes. Expected: BIOL 0800 or NEUR 1020. Enrollment limited to 20. Instructor's permission required.
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BIOL 1200: Protein Biophysics and Structure
1.00 Credits
Brown University
Structural Biology is the science to determine three-dimensional structures of biomacromolecules, e.g. proteins, RNA and DNA. These structures enable biologists to understand and explore their function. Since proteins, RNA and DNA are the primary molecules of life, structural biology enables us to understand and influence these molecular machineries which form the basis of all biological process. Expected: BIOL 0280.
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BIOL 1210: Synthetic Biological Systems
1.00 Credits
Brown University
A multidisciplinary course that combines science and engineering providing a solid foundation in a cutting edge field of biological engineering. Synthetic biology is a mixture of biology, chemistry, engineering, genetic engineering and biophysics. It builds on recent work in systems biology which involves the modeling of biological systems, but goes further in that it involves the construction and standardization of biological parts, that fit together to form more complex systems. Expected: at least two courses in any of the key disciplines (biology, chemistry, physics, math, engineering, computer science) beyond the introductory level. Instructor permission required.
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BIOL 1220: Synthetic Biological Systems in Theory and Practice
1.00 Credits
Brown University
A multidisciplinary laboratory, lecture, and discussion based course that combines several areas of science and engineering providing a foundation in the cutting edge field of synthetic biological engineering. The field of synthetic biology is centered around trying to make biology easier to engineer. It builds on recent work in systems biology which involves the modeling of biological systems, but goes further in that it involves the construction and standardization of biological parts that fit together making complex systems. This course will combine classes, guest lectures and discussion lab visits to give students the best possible tools for understanding and applying research in synthetic biology. Expected: at least two courses in any of the key disciplines (biology, chemistry, physics, math, engineering, computer science) beyond the introductory level, and permission of the instructor.
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BIOL 1260: Physiological Pharmacology
1.00 Credits
Brown University
Covers the physiology of human disease (e.g., Heart failure and arrhythmia; cancer signaling pathways with a focus on breast cancer; neurological disorders such as schizophrenia and Parkinson's disease) and discusses the pharmacology of the drugs used to treat the disease. A group of the most commonly prescribed drugs is discussed in terms of their fundamental modes of action and clinical importance. Expected: BIOL 0800.
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BIOL 1270: Advanced Biochemistry
0.00 - 1.00 Credits
Brown University
An advanced course in biochemistry, biochemical methods, and reading of the primary literature, featuring systematic coverage of the biochemistry of the central dogma, including DNA (replication, repair, recombination), RNA (regulation and mechanism of transcription, processing, turnover), and proteins structure, synthesis, modification, degradation, mechanisms of action, function). Lectures complemented by review sessions and laboratory exercises. Expected: BIOL 0280, CHEM 0350, 0360. Graduate students register for BIOL 2270. Students MUST register for the lecture section and a lab.
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