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Biol 437: Laboratory on DNA Manipulation
4.00 Credits
Washington University in St Louis
An introduction to laboratory techniques for experimental manipulation of DNA (and RNA) molecules, including construction, isolation, and analysis of plasmids, RNA, PCR products and sequencing. Molecular cloning experiments, RNA isolation, RT-PCR, Southern analysis and plant transformation are performed as class projects. Prerequisites: Biol 2970, Chem 152, and permission of instructor. One hour of lecture and eight hours of laboratory each week. This course fulfills the upper-level laboratory requirement for the Biology major. Enrollment is limited to 18.
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Biol 450W: Topics in the History of Eugenics
3.00 Credits
Washington University in St Louis
This is a research-based seminar that explores the history of eugenics both in the United States and abroad, roughly in the period 1890-1960. The seminar begins with reading of some of the seminal works in the history of eugenics coupled with a discussion of historiographical problems associated with this topic. The second part of the seminar is devoted to reading primary sources on various topics (race-crossing, family pedigrees, inheritance of specific traits such as criminality, feeblemindedness, manic depression, pauperism, etc. The third part of the course examines the transformation of eugenics in the population control movement of the 1950s and 1960s. Students give class reports on various readings and prepare four short papers (five to seven pages) as part of the writing-intensive requirement. Emphasis is on both the biological content and social/economic/political context of eugenics work in the first half of the 20th century.
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Biol 450W - Topics in the History of Eugenics
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Biol 451: General Biochemistry
4.00 Credits
Washington University in St Louis
A study of structure-function relationships as applied to carbohydrates, proteins, and lipids; intermediary metabolism of principal cellular components; and general aspects of regulation. Prerequisites: Biol 2970 and Chem 252 and permission of department. Recommended for students who have achieved grades of B or better in the prerequisites. Students may not receive credit for both Biol 4801 and Biol 451. Small class.
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Biol 451 - General Biochemistry
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Biol 4522: Laboratory in Protein Analysis, Proteomics and Protein Structure
3.00 Credits
Washington University in St Louis
In this laboratory course, students learn principles and methods of protein quantitation, protein purification, assessment of purity using SDS-polyacrylamide gel electrophoresis, separation of complex protein mixtures by two-dimensional gel electrophoresis, definition of units of enzymatic activity, and identification of proteins using antibodies and/or mass spectrometry. The final part of the course introduces students to concepts of structural biology including protein crystallization, X-ray crystallography, and computer modeling of protein structures. Fulfills the upper-level laboratory requirement for the Biology major. Prerequisites: Chem 252 and either Biol 451 or Biol 4501/Chem 456. Permission of instructor required. Limit: Eight students. Eight hours of laboratory/lecture per week.
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Biol 4522 - Laboratory in Protein Analysis, Proteomics and Protein Structure
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Biol 4580: Principles of Human Anatomy and Development
3.00 Credits
Washington University in St Louis
Same as Anthro 4581
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Biol 4580 - Principles of Human Anatomy and Development
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Biol 4810: General Biochemistry I
3.00 Credits
Washington University in St Louis
Same as Chem 481
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Biol 4810 - General Biochemistry I
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Biol 4820: General Biochemistry II
3.00 Credits
Washington University in St Louis
Continuation of General Biochemistry I. Topics include carbohydrate, lipid and amino acid metabolism, signal transduction, transport across membranes, DNA replication and repair, transcription and translation, molecular motors, mechanisms of drug action and natural products biosynthesis. Prerequisite: Chem 481 or Biol 481.
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Biol 4820 - General Biochemistry II
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Biol 4830: Bioenergy
2.00 Credits
Washington University in St Louis
A broad overview of the flow of energy, captured from sunlight during photosynthesis, in biological systems, and current approaches to utilize the metabolic potentials of microbes and plants to produce biofuels and other valuable chemical products. An overall emphasis is placed on the use of large-scale genomic, transcriptomic, and metabolomic datasets in biochemistry. The topics covered include photosynthesis, central metabolism, structure and degradation of plant lignocellulose, and microbial production of liquid alcohol, biodiesel, hydrogen, and other advanced fuels. Course meets during the second half of the spring semester. Prerequisite: Biol 4810 or permission of instructor.
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Biol 4830 - Bioenergy
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Biol 487: Undergraduate Teaching
1.00 - 3.00 Credits
Washington University in St Louis
Exceptional undergraduates serve as teaching assistants for laboratory and/or discussion sections in departmental courses. Normally 2 or 3 units are given per semester, subject to the approval of the instructor and the department. Credit may not be counted toward fulfilling the biology major; application form in Department of Biology Student Affairs office. Prerequisite: permission of instructor. Credit/no credit only.
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Biol 487 - Undergraduate Teaching
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Biol 493: Seminar in Advanced Biology
1.00 - 4.00 Credits
Washington University in St Louis
In special cases, credit may be given for individual study. Topics of study and credit must be arranged with a faculty sponsor and approved by the department.
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Biol 493 - Seminar in Advanced Biology
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