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Course Criteria
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0.00 Credits
No course description available.
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0.00 Credits
No course description available.
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3.00 Credits
This course focuses on the study of the body¿s immune system and its mechanisms of defense against disease and allergies. The immunologic response of host mechanisms in terms of the biochemistry of antigens and antibodies and the biology of the immune response including both harmful and beneficial aspects of the functions of cells, organs, and molecules of the immune system are covered in this course. Finally, the therapeutic agents that affect the immunologic response will also be considered.
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3.00 Credits
This course is an introduction to the classification, morphology and physiology of microorganisms, particularly bacteria, fungi and viruses. The course emphasizes the classification of microorganisms, their pathogenesis and epidemiology, microbial virulence and host defense mechanisms. Therapeutic agents used to disrupt and control microbial growth will be considered.
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3.00 Credits
This course is designed to give pharmacy students an introduction to the study of disease, both congenital and acquired. Emphasis is placed on providing students with an understanding of alterations and derangement of normal physiology due to disease or injury as manifest by signs, symptoms, physical and laboratory findings. The topics discussed in the course will include but are not limited to: biology of cancer and alterations in the immune, neurological, reproductive, cardiovascular, pulmonary, renal and digestive systems. Students will create fictitious case studies and present them to each other in small groups.
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3.00 Credits
Pharmacogenomics is the study of how an individual's genetic inheritance affects the body's response to drugs. This course will combine traditional pharmaceutical sciences such as biochemistry and pharmacology with the acquired knowledge from the human genome and individual patients with variations in their genes and associated proteins. This information is being gathered and stored as a database at Stanford University and is called the Pharmacogenomics Knowledge Base (PharmGKB). The database describes the location and frequency of variations in human genome sequences that effect drug response with referenced journal articles containing data from research laboratories and clinical institutions. This database will be the primary resource for this course. The College of Pharmacy faculty and guest lecturers will present seminars and have problem solving sessions incorporating the following disciplines: clinical outcomes, drug response, pharmacokinetics, molecular biology and cellular function. In the future, pharmacists will be involved in the genotyping of patients before medicines are prescribed to increase efficacy and decrease side effects.
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3.00 Credits
This course is concerned with the processes and mechanisms controlling the rate and extent of drug absorption and systemic availability. Bioavailability and bioequivalence determination and interpretation and implications regarding pharmaceutical care will be discussed. Routes of drug administration will be considered including transdermal, otic, sublingual, ophthalmic, pulmonary, nasal, oral, vaginal, rectal, subcutaneous, intravenous and intramuscular. Pharmacokinetic and pharmacodynamic concepts, as necessary for complementing the understanding of biopharmaceutics, will be presented.
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3.00 Credits
Medicinal Chemistry is an interdisciplinary science that also involves aspects of biochemistry, physical chemistry and pharmacology. This introductory course emphasizes the principles of drug discovery and drug design, the relationship of functional groups to pharmacologic activity, receptors and drug action, peptide and protein drugs, and drug metabolism. Also drug receptors affecting neurotransmission and enzymes as catalytic receptors will be covered in detail. This course will be taught concurrently with Pharmacology I using an integrated approach. Emphasis will be placed on cardiovascular/renal drug molecules in the first semester.
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3.00 Credits
This course is a continuation of Medicinal Chemistry I and emphasizes the structure of drug molecules used to treat disease states. This course will be taught concurrently with Pharmacology II using an integrated, disease-management approach. Emphasis will be placed on drug molecules that act on smooth muscle, the central nervous system, the endocrine system, drugs used to treat diseases of the blood and inflammation, antibiotics and cancer chemotherapeutic agents. For each class of drugs, material will be presented examining the mechanism of action, including the interaction with receptors or enzymes at the molecular level. This course will also discuss the chemical modification of drug molecules during metabolism and excretion.
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3.00 Credits
This course will provide a comprehensive review of pharmacology over two semesters. The emphasis of this course will be on drug mechanism at the cellular and receptor level. The course will present therapeutic classes of drugs in correlation with disease states and will be taught concurrently with Medicinal Chemistry I. Topics of discussion will include an introduction to autonomic drugs (cholinergic and adrenergic agonists and antagonists). Cardiovascular/renal drug topics will include anti-hypertensive agents, vasodilators and the treatment of angina, drugs used in heart failure and drugs used for the treatment of cardiac arrhythmias. Students will create case studies and present them to each other in small groups.
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