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Course Criteria
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3.00 Credits
Detailed overview of regulations and best practices in the medical device reprocessing industry. Covers device design, usability, material selection, and manufacturing techniques with an emphasis on remanufacturing, reprocessing and sustainability. Addresses Quality System Regulations and compliance with global standards for process verification and validation in healthcare and industry settings. Preq: Senior standing in the College of Engineering, Computing and Applied Sciences or the College of Science.
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3.00 Credits
This course examines the design principles necessary to use bacteria, fungi, and mammalian cells in bioengineering applications, including molecular techniques, fermentation, process scale-up, purification processes, and FDA regulations. The production of biopharmaceuticals derived from recombinant systems, including uses in medical systems, in emphasized.
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3.00 Credits
This course provides an overview of the basis of genes, the process of how the genetic code gives rise to proteins and is regulated in eukaryotic cells and genetic mutations. It also covers delivery methods and cutting-edge molecular tools for altering protein expression, manipulating the genome, design, analysis and their applications. The applications of gene editing for making model organisms for biomedical studies, gene therapy for inherited and acquired diseases and control of vector borne diseases are explored. The final portion of the course addresses the ethical and biosafety considerations of gene editing.
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4.00 Credits
Study of engineering principles involved in the production of complex living and non-living biological products (tissue/organ replacements biosensors, bio-based diagnostics) from raw materials, such as living cells, molecules, extracellular matrices, and biomaterials. Coreq: BIOE 6451.
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0.00 Credits
Non-credit laboratory to accompany BIOE 6450. Coreq: BIOE 6450.
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3.00 Credits
Synthetic biology applies engineering principles to design and implement new biological systems and living organisms. This course covers approaches and tools for biological design, modeling, implementation, and debugging. Topics include gene regulatory networks, DNA assembly, modeling, biosensor development, and applications in the clinic, industry, and the environment.
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3.00 Credits
Introduces drug design, development and delivery in the context of creating biomaterial-based prodrugs and applying pharmaceutical therapies in tissue engineering/regenerative medicine. This course covers the relationship between drug physics-chemical properties and pharmacokinetics (ADME: Absorption, Metabolism, Distribution and Elimination)/pharmacodynamics (mechanism of drug interaction). Methods are described to improve the therapeutic efficacy and reduce the toxicity of drugs for the efficient treatment of diseases and regeneration of tissue/organs. This course also provides students with an understanding of the principles, strategies and biomaterials used in controlled delivery systems, targeted delivery systems and tissue engineering.
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3.00 Credits
Biophotonics is an interdisciplinary subject of applying photonics to study biological samples from individual cells to the entire body. Introduces fundamental and frontier topics in optical imaging aspects of biophotonics for senior-level undergraduates and graduate students to gain the ability to solve bioimaging-related biomedical problems.
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3.00 Credits
Provides training in the planning and conduct of experimental surgery, including laws and regulations; institutional requirements; selection of animal models; ethical considerations of animal research; preparation of animals for surgery; general and special surgical techniques; aseptic surgical techniques; and basic and applied instrumentation. Coreq: BIOE 6821.
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0.00 Credits
Non-credit laboratory to accompany BIOE 6820. Coreq: BIOE 6820.
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