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BIOE 4310: Medical Imaging
3.00 Credits
Clemson University
Introduction to the history, physics, and instrumentation of various medical imaging modalities; including X-ray, Computed Tomography, Magnetic Resonance Imaging, and Ultrasound. Students learn the principles of medical imaging from an engineering and clinical prospective. Students evaluate clinical images and explain the clinical applicability among different modalities. Preq: MATH 2080; and one of ECE 2020 or ECE 2070. Preq or concurrent enrollment: BIOE 3700.
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BIOE 4340: Cardiovascular Biomechanics
3.00 Credits
Clemson University
Provides the critical background knowledge for an engineer to thoroughly consider important aspects of the human cardiovascular system relevant to investigations of cardiovascular computational modeling, medical device design, and surgical treatment planning. May also be offered as ME 4340. Preq: One of the following courses with a grade of C or better: BIOE 3200, BIOE 3700, ECE 3300, or ME 3050.
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BIOE 4350: Computational Modeling in BIOE
3.00 Credits
Clemson University
This course introduces students to computational modeling applied to bioengineering problems. Students use modeling approaches (finite element, agent-based, systems network, simple differential equations, etc.) to predict, analyze and engineer biologically-relevant processes-drug diffusion, biomaterial interactions, biomechanics performance, bioelectrical conduction, cellular signaling, and tissue remodeling. Preq: MATH 2080.
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BIOE 4380: Engr Validation Microbio Sys
3.00 Credits
Clemson University
Detailed overview of cleaning, disinfection/sterilization, and packaging requirements for reprocessing medical devices. Emphasizes biocompatibility, process controls, and cleaning/disinfection/sterilization systems in manufacturing and healthcare sectors. It includes a laboratory for developing skills and techniques for working with bacteria safely and applying fundamental concepts of biology and biochemistry to problems related to medical device cleaning, disinfection, and sterilization. Addresses compliance with global regulations and standards, including instructions for use, methods for cleaning and sterilization validation, equipment design, and packaging processes. Coreq: BIOE 4381.
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BIOE 4381: Eng Validation Microbio Sy Lab
0.00 Credits
Clemson University
Non-Credit Laboratory to accompany BIOE 4380. Coreq: BIOE 4380.
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BIOE 4390: Intro Medical Device Reprocess
3.00 Credits
Clemson University
Detailed overview of regulations and best practices in the medical device reprocessing industry. Covers device design, usability, material selection, and manufacturing techniques with an emphasis on remanufacturing, reprocessing and sustainability. Addresses Quality System Regulations and compliance with global standards for process verification and validation in healthcare and industry settings. Preq: Senior standing in the College of Engineering, Computing and Applied Sciences or the College of Science.
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BIOE 4400: Biopharmaceutical Engineering
3.00 Credits
Clemson University
This course examines the design principles necessary to use bacteria, fungi, and mammalian cells in bioengineering applications, including molecular techniques, fermentation, process scale-up, purification processes, and FDA regulations. The production of biopharmaceuticals derived from recombinant systems, including uses in medical systems, in emphasized. May also be offered as CHE 4400. Preq: BCHM 3010 or BCHM 3050.
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BIOE 4420: Biomed App Gene Reg & Editing
3.00 Credits
Clemson University
This course provides an overview of the basis of genes, the process of how the genetic code gives rise to proteins and is regulated in eukaryotic cells and genetic mutations. It also covers delivery methods and cutting-edge molecular tools for altering protein expression, manipulating the genome, design, analysis and their applications. The applications of gene editing for making model organisms for biomedical studies, gene therapy for inherited and acquired diseases and control of vector borne diseases are explored. The final portion of the course addresses the ethical and biosafety considerations of gene editing. Preq: BCHM 3010 or BCHM 3050.
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BIOE 4450: Biofabrication
4.00 Credits
Clemson University
Study of engineering principles involved in the production of complex living and non-living biological products (tissue/organ replacements biosensors, bio-based diagnostics) from raw materials, such as living cells, molecules, extracellular matrices, and biomaterials. Preq: BIOE 3020 and BIOE 3200. Coreq: BIOE 4451.
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BIOE 4451: Biofabrication Lab
0.00 Credits
Clemson University
Non-credit laboratory to accompany BIOE 4450. Coreq: BIOE 4450.
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