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Course Criteria
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3.00 Credits
The relationship between genotype and behavioral phenotype. Readings from the primary literature, including papers on humans, lab mice, and wild animal populations. Exploration of two philosophical topics: the question of causality in the natural world and the question of determinism in biology. Short research paper required. Instructor: Alberts
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3.00 Credits
Lectures, seminars, and discussion of current topics in developmental biology. Prerequisites: Biology 101L or 118 and/or 119 or equivalent. Instructor: Sherwood
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3.00 Credits
Applications of recombinant DNA in medicine and in agriculture. Topics include diagnosis of genetic diseases, gene therapy, drugs for AIDS and cancer, DNA fingerprinting, cloning of mammals, phytoremediation, crop improvement, and pharmaceutical protein production in transgenic plants and animals. Social and environmental impacts of biotechnology. Prerequisites: Biology 101L or 118 and 119 or consent of instructor. Instructor: Sun
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3.00 Credits
Lectures, seminars, and discussion of current topics in systems biology. Introduction to both experimental and quantitative approaches to understanding the function of biological networks. Weekly lectures by experts in the field. Instructor: Haase
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2.00 Credits
Half-semester minicourse targeted to first-year graduate students in the Biological Sciences. Taught sequentially in the Fall semester with Biology 283. Introduces basic concepts of cell specification, morphogenesis, induction, and other mechanisms that enable cells, tissues and organs to assemble the animal. Emphasis is on model organisms, mainly Drosophila, C. elegans, mouse, and zebrafish, where genomics, mutations, gene modifiers, epistasis analyses, gene knockouts, and transgenesis, plus many other genetic approaches have yielded important insights into the differentiation of cells and the development of complex organisms. Cross-listed with Biology 282. Instructors: Kirby, Klingensmith, and McClay
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2.00 Credits
Half-semester mini-course targeted to first year graduate students in the Biological Sciences. Taught sequentially in the Fall semester with Biology 282. Focuses on genetic approaches to solve mechanistic problems of development. Emphasis is on model organisms, mainly Drosophilia, C. elegans, mouse and zebrafish, where genomics, mutations, gene modifiers, epistasis analysis, gene knockouts, and transgenesis, plus many other genetic approaches have yielded important insights into the differentiation of cell and the development of complex organisms. Cross-listed with Biology 283. Instructors: Kirby, Klingensmith, and McClay
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3.00 Credits
Genetic mechanisms of evolutionary change at the DNA sequence level. Models of nucleotide and amino acid substitution; linkage disequilibrium and joint evolution of multiple loci; analysis of evolutionary processes, including neutrality, adaptive selection, and hitchhiking; hypothesis testing in molecular evolution; estimation of evolutionary parameters; case histories of molecular evolution. For graduate students and undergraduates with interests in genetics, evolution, or mathematics. Instructor: Uyenoyama
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3.00 Credits
Readings and discussion of current literature on epigenetics and plasticity. A comparative look at epigenetic factors in mediating plasticity in biological systems from neuronal learning to development and aging. Prerequisites: Biology 118 or Biology 101L and PSY 101RE. Instructor: Volkan
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3.00 Credits
Evolutionary patterns and processes at and above the species level; species concepts, speciation, diversification, extinction, ontogeny and phylogeny, rates of evolution, and alternative explanations for adaptation and evolutionary trends. Prerequisite: Biology 25L, 26L, 102L, or other course in plant or animal diversity; recommended, Biology 116 or equivalent. Instructor: Roth
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3.00 Credits
Lectures, seminars, and discussion of current research in ecology and evolution. Guest lectures will focus on research at Duke. Intended for advanced undergraduates. Prerequisites: Biology 116 or 102L and one course in ecology. Instructor: J. Noor
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