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Course Criteria
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1.00 Credits
Introductory course for students planning to major in biology and for students in other majors intending to pursue a postgraduate degree in the life sciences. Provides an integrated overview of biology, covering basic principles in cell and molecular biology, energy transport, development, physiology, genetics, microevolution, macroevolution, and ecology. Instructors: Alberts, Grunwald, McClay, or Motten, and staff
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3.00 Credits
Overview of the genetic changes associated with cancer and the molecular events that transform normal cellular processes into tumor-promoting conditions. Topics include: tumor viruses, oncogenes, growth factors, signal transduction pathways, tumor suppressors, cell cycle control, apoptosis, stem cells, and metastasis. Prerequisites: Biology 101L and 102L or Biology 118. Recommended: Biology 117 or 119. Instructor: Bejsovec
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3.00 Credits
Seminar course designed to help students understand research talks by working scientists, such as those presented in the Developmental Biology Colloquium and the UPGG and CMB seminar series at Duke. Read and discuss research papers that use the yeast, C. elegans, and Drosophila genetic model systems to study cellular processes at the molecular level. Topics will include forward and reverse genetic screen strategies, gene manipulation and expression analysis, somatic mosaics and transgenics. Prerequisites: Biology 118, or Biology 101 and 102, or equivalent molecular genetics course.
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3.00 Credits
Processes responsible for natural biodiversity from populations to the globe. Topics include species interactions (e.g., competition, predation, parasitism), natural and human disturbance, climate change, and implications for management and conservation. Lab section involving observation and data from large-scale manipulations, such as experimental hurricanes, fire, and herbivore exclosures. Instructors: Clark and Wright
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3.00 Credits
Formulation of environmental models and applications to data. Topics include physiology, population growth, species interactions, disturbance, and ecosystem dynamics. Model development, analysis, and interpretation. Discussions focus on classical and current primary literature. Lab focuses on analysis of data using R, making use of likelihood models, bootstrapping, and Bayesian approaches. Instructor: Clark
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4.00 Credits
Introduction to the field of genomics. Genomic techniques including genome sequencing, microarray analysis, proteomics, and bioinformatics; applications of genomics to understanding biological problems including biological networks, human origins, evolution; applications to medicine and agriculture. Computer-based research lab with participation in colloborative bioinformatics projects. Prerequisites: Biology 101L or 118 or consent of instructor. Instructor: Spana
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3.00 Credits
Processes controlling the circulation of carbon and biochemical elements in natural ecosystems and at the global level, with emphasis on soil and surficial processes. Topics include human impact on and social consequences of greenhouse gases, ozone, and heavy metals in the environment. Prerequisite: Chemistry 31L or equivalent; Recommended: Chemistry 32L. Instructor: Bernhardt
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3.00 Credits
Human evolutionary history as studied from the perspective of the genome. Nature of contemporary genomic data and how they are interpreted in the context of the fossil record, comparative anatomy, psychology, and cultural studies. Examination of both the origin of modern humans as a distinct species and subsequent migration across the world. Emphasis on language, behavior, and disease susceptibility as traits of particular evolutionary interest. Prerequisite: Biology 101L and 102L or 118 or equivalent course. Instructor: Wray
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3.00 Credits
Recent progress in sensory signal transduction mediated by calcium channels and receptors. Topics include history and techniques in the study of ion channels, such as electrophysiology, calcium imaging, and cell and molecular biology; cell surface perception for external signals, including light receptors, olfactory receptors, taste receptors, hot and cold receptors, and mechanical receptors; heart and brain pacemakers; sensory channel receptor-related human diseases; and plan sensory signaling network. Instructor: Pei
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3.00 Credits
Readings on behavioral ecology, both historical papers and papers from the current literature that represent the most vital areas of research in the discipline. Instructors: Alberts
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