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BIOLOGY 115: Cellular and Molecular Neurobiology
1.00 Credits
Duke University
This course will cover the molecular and cellular components underlying nervous system function. Topics include the regulation of the neuronal cytoskeleton, process outgrowth and axon guidance, transport mechanisms, the generation and propagation of the action potential, components of the presynaptic and postsynaptic terminals, growth factors in development and regeneration, neuronal stem cells, and sensory signal transduction. Lectures by the instructor and expert guests, with regular readings of current and/or historical primary literature. Prerequisites: Biology 19 or 25L or 101L or equivalent, and Psychology 101RE. Instructor: Sherwood or Volkan
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BIOLOGY 116: Fundamentals of Ecology and Evolution
1.00 Credits
Duke University
Fundamental principles of ecology and evolutionary biology. Interaction between biotic and abiotic forces in shaping the dynamics of ecological systems, and how those dynamics are influenced by human activities. Mechanisms of evolutionary change as an interplay between ecology and genetics. Evidence for, and consequences of, evolutionary change on both human and geological time scales. Prerequisite: Biology 25L. Not open to students who have taken Biology 110L or 120. Instructor: Bernhardt, Koelle, Mercer, Morris, Rausher, Uyenoyama, or Wilson
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BIOLOGY 117: Cell and Organismal Physiology
1.00 Credits
Duke University
Mechanisms and processes that organisms use to deal with the challenges posed by their physical, chemical, and ecological contexts. Structure-function relationships explored from molecules and cells to tissues and organ systems. Topics include cellular architecture, energy metabolism, molecular motors, motility/locomotion, sensory mechanisms/signal transduction, ionic/osmotic balance, gas exchange, thermal physiology. Constraints and adaptations related the evolution of eukaryotes and the evolution of multicellularity. Prerequisite: Biology 25L or 101L or equivalent. Not open to students who have taken Biology 119 or 151 or 151L. Instructor: Magwene, Nijhout, or staff
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BIOLOGY 118: Genetics and Molecular Biology
1.00 Credits
Duke University
Explores flow of information from gene to phenotype. Social implications of modern genetic analysis and the genomic revolution. Topics include: organization and stability of genomes from bacteria to higher vertebrates (humans), conversion of the genetic code into a functioning organism, classical transmission (Mendelian) genetics and its relevance to human hereditary disorders, content of the genome and social implications of genetic knowledge including issues of genetic privacy, eugenics, genetically modified organism, and cloning. Prerequisite: Biology 25L or equivalent; Chemistry 31L or equivalent. Instructor: Bejsovec, Haase, Mitchell-Olds, Sun, or staff
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BIOLOGY 119: Cellular and Developmental Biology
1.00 Credits
Duke University
The role of genes and proteins in mediating basic cellular and development processes. Topics include: structure and function of cellular membranes and organelles; protein targeting and transport; signal transduction; role of the cytoskeleton in cell shape and motility; function of the immune system; genetic regulation of cell growth/division and the relationship to cancer; genetic control of development processes. Prerequisite: Biology 101L or 118. Instructor: Baugh, Chen, Kiehart, McClay, Pei, D. Sherwood, or staff
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BIOLOGY 119 - Cellular and Developmental Biology
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BIOLOGY 120: Cell Signaling and Diseases
1.00 Credits
Duke University
During the past several decades, exploration in basic research has yielded extensive knowledge about the numerous and intricate signaling processes involved in the development and maintenance of a functional organism. In order to demonstrate the importance and processes of cellular communication, this course will focus on cell signaling mechanisms and diseases resulting from their malfunction, such as cancer, stroke, and neuron degeneration (including Parkinson¿s disease, Alzheimer¿s disease, Huntington¿s disease, and Amyotrophic lateral sclerosis). Students will be exposed to current literature and cutting edge knowledge. Prerequisite: Biology 101L. Instructor: Chen and Pei.
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BIOLOGY 121: Evolution of Animal Form
1.00 Credits
Duke University
A survey of the history of animal life focusing on major revolutions in design such as the Cambrian explosion, the Mesozoic radiation of dinosaurs, and the Cenozoic radiation of mammals. Exploration of three views of form: the Darwinian view which stresses function; the historicist view which emphasizes historical accident; and the structuralist view that form is mainly the result of fixed mathematical relationships. The different ways in which each view applies the comparative method. Prerequisite: Biology 19 or 25L or 102L. Instructor: McShea
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BIOLOGY 122: Population Genetics
1.00 Credits
Duke University
Use of genetic sequence analysis to examine aspects of natural populations of humans and other organisms in the past and present. Topics include molecular phylogenetics; the origin, maintenance, and loss of major features of evolution; the evolutionary process at the molecular level; reconstruction of human origins and paleohistory; and genetic information in forensic studies. Prerequisite: Biology 19 or 25L or 102L or equivalent. Instructor: Uyenoyama
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BIOLOGY 123: Analysis of Ocean Ecosystems
1.00 Credits
Duke University
The history, utility, and heuristic value of the ecosystem; ocean systems in the context of Odum's ecosystem concept; structure and function of the earth's major ecosystems. (Given at Beaufort.) Prerequisite: one year of biology, one year of chemistry, or consent of instructor. Instructor: Johnson
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BIOLOGY 124: Molecular Evolution
1.00 Credits
Duke University
Evolutionary dynamics of genes in populations, molecular phylogenetics, evolutionary pattern and process at the molecular level and some of their consequences for organism-level evolution. Evolution of genomes, gene families, gene function, regulatory genes, and of developmental control genes. Prerequisite: Biology 25L or equivalent, and Biology 118 or 101L, and 102L or AP Biology, or consent of instructor. Instructor: Mercer
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