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Course Criteria
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2.00 Credits
Mechanisms of transcription, splicing, catalytic RNA, RNA editing, mRNA stability and translation. Mini-course, 2nd half semester. Instructors: Steege and Staff
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3.00 Credits
Basic principles of physical chemistry as applied to biological systems. Topics include thermodynamics, kinetics, statistical mechanics, spectroscopy, and diffraction theory. Concepts discussed in the context of the biochemistry and behavior of biological macromolecules. Emphasis on quantitative understanding of biochemical phenomena, with extensive problem solving as an instructive tool. Prerequisite: undergraduate physical chemistry and one year of calculus. Instructor: Oas and staff
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3.00 Credits
Basic and current concepts of the biological membranes, membrane proteins and organization; mechanism of action of hormones at the cellular level including hormone-receptor interactions, secondary messenger systems for hormones, mechanism of regulation of hormone responsiveness, regulation of growth, differentiation and proliferation, cellular electrophysiological mechanisms of transport and ions channels, secretory and sensory stimulus sensing and transduction. Some lectures stress the clinical correlation of the basic concepts in the course. C-L: CELLBIO-317B; Graduate School. Credit: 3. Caron, Casey, and invited lecturers
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1.00 - 8.00 Credits
In a limited number of cases, a student is permitted to participate in the research program of a faculty member. Acceptance is by individual arrangement with the proposed faculty preceptor. Credit: 1-16. Staff
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1.00 - 16.00 Credits
A student may obtain first hand research experience by participating in the research program of a faculty member. Acceptance is by individual arrangement with the proposed faculty preceptor. Credit: 1-16. Staff
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4.00 Credits
Basic enzymology, mechanisms of enzymatic reactions, cofactors, oxidoreductases, C1 chemistry, carbon-carbon bond formation, carboxylation/decarboxylation, heme, pyridoxal enzymes, thiamine enzymes. Prerequisite: Chemistry 331 or equivalent. Instructor: Toone
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1.00 Credits
Required of all second- and third-year biochemistry students. Credit/no credit grading only. Instructor: Staff
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1.00 Credits
Introduces major concepts in biology through the lens of molecular biology. Molecular mechanisms that comprise the Central Dogma and variants. DNA structure and function, replication, transcription, and translation. Protein synthesis, folding, structure and function. Supporting topics related to the structure of cells, metabolism and energetics. Integration of physical and quantitative principles to molecular biology. Relevance to human diseases and the biotechnology industry. Laboratory includes an introduction to recombinant DNA technology. Prerequisite: Chemistry 31L, or equivalent. Instructor: Buchler, Haase, Kiehart, Wray
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1.00 Credits
Introduction to principles transmission genetics and evolution. Includes Mendelian and non-Mendelian inheritance, quantitative genetics, genetic mapping, evidence for evolution, natural selection, genetic drift, kin selection, speciation, molecular evolution, phylogenetic analysis. Relevance to human family and social structure, evolution of infectious disease, human hereditary disorders, social implications of genetic knowledge. Instructor: Donohue, Noor, Rausher, Willis or staff
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1.00 Credits
Classical and modern principles of the structure, physiology, and genetics of microorganisms and their roles in human affairs. Prerequisite: one course in a biological science or consent of instructor. Instructor: Dong, Lutzoni, Schmid, or Vilgalys
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