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CHEM 302: Spectrochemical Analysis
2.00 Credits
Duke University
Advanced topics in spectroscopic analysis, emphasizing absorption, emission, and luminescence techniques and applications to biomolecules. Prerequisite: Chemistry 301 or consent of instructor. Instructor: Staff
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CHEM 302 - Spectrochemical Analysis
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CHEM 304: Separation Science
2.00 Credits
Duke University
Fundamental separation chemistry, practical aspects of chromatographic methods, larger scale processes. Prerequisite: Chemistry 301 or consent of instructor. Instructor: Staff
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CHEM 304 - Separation Science
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CHEM 306: Biomolecular Mass Spectrometry
2.00 Credits
Duke University
Advanced topics in the mass spectral characterization of biopolymers with an emphasis on protein and DNA analysis. Fundamental and practical aspects of the ionization processes and the instrumentation associated with MALDI- and ESI-Mass spectrometry discussed along with applications of these techniques to structural problems in chemistry and biochemistry. Prerequisite: Chemistry 301 or consent of instructor. Instructor Fitzgerald
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CHEM 306 - Biomolecular Mass Spectrometry
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CHEM 307: Biosensors
3.00 Credits
Duke University
Biosensors (GE, IM, MC). Biosensors are defined as the use of biospecific recognition mechanisms in the detection of analyte concentration. The basic principles of protein binding with specific reference to enzyme-substrate, lectin-sugar, antibody-antigen, and receptor-transmitting binding. Simple surface diffusion and absorption physics at surfaces with particular attention paid to surface binding phenomena. Optical, electrochemical, gravimetric, and thermal transduction mechanisms which form the basis of the sensor design. Prerequisites: Biomedical Engineering 83L and 100L or their equivalent and consent of instructor. Instructors: Reichert or Vo-dinh.
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CHEM 307 - Biosensors
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CHEM 309: Special Topics in Analytical Chemistry
1.00 - 4.00 Credits
Duke University
An advanced treatment of important areas in modern analysis. Topics may include: electrochemistry, small computer applications, magnetic resonance, and problem-solving approaches. 1 to 4 units. Instructor: Staff
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CHEM 309 - Special Topics in Analytical Chemistry
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CHEM 311: Biological Chemistry
4.00 Credits
Duke University
Chemistry of the major classes of biological molecules, including nucleic acids, amino acids and proteins, carbohydrates and lipids. Topics include structure, reactivity and synthesis, and the interaction of biological molecules. Instructors: Hong, McCafferty, Shaw, and Toone
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CHEM 311 - Biological Chemistry
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CHEM 312: Chemistry and Biology of Nucleosides, Nucleotides, and Nucleic Acids
4.00 Credits
Duke University
Synthesis, biosynthesis, and reactivity of nucleic acids and their polymers. Mechanisms of DNA and RNA coding, decoding, transmission, and in vitro evolution. Covalent and reversible interactions of nucleic acids with small molecules and macromolecules. Instructors: Hong, McCafferty, Shaw, and Toone
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CHEM 312 - Chemistry and Biology of Nucleosides, Nucleotides, and Nucleic Acids
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CHEM 314: Chemical Genomics
2.00 - 4.00 Credits
Duke University
Information transfer, restructuring, and decoding in biological systems. Gene expression and evolution of function. Functional consequences of gene expression. Instructors: Shaw and Toone
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CHEM 314 - Chemical Genomics
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CHEM 315: Advanced Biomedical Imaging Seminar
1.00 - 3.00 Credits
Duke University
For grad students in BME, Chem, MSTP focusing on imaging from three distinct perspectives: (i) technology (x-ray based, magnetic resonance, optical, and sonographic modalities), (ii) design and synthesis of imaging probes (cellular, vascular, targeted probes), and (iii) imaging paradigm (anatomical , functional, metabolic, etc.). Recent publications on diverse topics: molecular imaging, contrast agent development, cellular imaging, nanotechnology, hardware design, image guided therapy, interventional imaging and drug delivery, and data analysis and reduction. MatLab, and ImageJ extensively used in course. Choice of topics determined at beginning of each semester to reflect projects of members of seminar series. Course can be taken up to 3 times, as content will change to address varying perspectives. Consent of instructor required. Instructor: Mukundan
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CHEM 315 - Advanced Biomedical Imaging Seminar
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CHEM 316: Techniques in Biochemistry
2.00 Credits
Duke University
Purification and study of biological molecules including macromolecules. Chromatography, spectroscopy (IR, UV/vis, fluorescence, CD), electrophoretic methods, immunological methods, analytical ultracentrifugation, and their application to the study of biomolecules. Instructors: Fitzgerald, Hong, McCafferty, Shaw, and Toone
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CHEM 316 - Techniques in Biochemistry
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