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Course Criteria
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1.00 - 4.00 Credits
Discussion and directed reading and/or observational work on a topic of interest to the individual student. Prerequisite: consent of instructor.
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1.00 - 3.00 Credits
An advanced interdisciplinary independent study project for astronomy-combined majors; students wishing to do a senior research project should choose project advisers and propose an interdisciplinary topic during the second semester of their junior year. Prerequisite: consent of instructor.
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4.00 Credits
Staff Preparation of an honors thesis. Required of and limited to senior honors candidates in astronomy. Prerequisite: admission to honors candidacy.
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3.00 Credits
This course presents the molecular side of the broad field of biophysics, in which physical concepts are applied to biological systems. Topics may include thermodynamics, equilibrium, quantum mechanics, statistical mechanics, classical mechanics and spectroscopy of biological systems such as membranes, proteins, and nucleic acids. Prerequisites: Physics 155 or 165, 156 or 166; Biology 111 or consent of instructor.
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3.00 Credits
The first semester of a yearlong sequence on the biochemistry and molecular biology of the living cell. Topics include an introduction to the techniques used to study biological macromolecules; characterization, structure, and function of proteins; enzyme kinetics, mechanisms, and regulation; composition of biological membranes; bioenergetics; and catabolism of proteins, fats, and carbohydrates. Three lectures per week. Prerequisites: Biology 111, Chemistry 246.
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3.00 Credits
The second semester of a yearlong sequence on the biochemistry and molecular biology of the living cell. Topics include a detailed examination of DNA and RNA, the mechanisms of DNA replication, transcription and translation, the control of gene expression in prokaryotes and eukaryotes, the molecular biology of viruses, oncogenes/cancer, mobile genetic elements, and genomics. Three lectures per week. Prerequisites: Biology 205 and BBMB 325.
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3.00 Credits
Laboratory exercises on a range of biophysical topics. Physical characterization of macromolecules using techniques that may include absorption spectroscopy, fluorescence spectroscopy, nuclear magnetic resonance, circular dichroism, crystallization and x-ray diffraction. Mathematical modeling and simulation of small molecules, macromolecules, and fluctuations in biological systems. Corequisite: BBMB 324. Required of BBMB majors. Open to other students only with consent of instructor.
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3.00 - 4.00 Credits
Laboratory exercises in protein biochemistry, which will include biochemical reagent preparation, enzyme isolation and purification, enzyme and protein assays, and gel electrophoresis. One three- to four-hour laboratory per week. Prerequisites: Biology 111 and Chemistry 136 or 140; Corequisite: BBMB 325. Chemistry 240 is strongly recommended. Required of BBMB majors. Open to other students only with consent of instructor.
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1.00 - 3.00 Credits
Laboratory exercises in nucleic acid biochemistry, with emphasis on molecular cloning and PCR techniques. One three-hour laboratory per week. Prerequisite: BBMB 335; Corequisite: BBMB 326.
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2.00 Credits
A team-taught seminar which will present recent developments in the molecular life sciences, such as bioinformatics, drug design, genomics, or self-assembly processes. In addition to participation in discussion, students will contribute oral presentations of recent research articles and of the senior research project. Required of BBMB seniors. Open to other students with consent of instructors.
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