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Course Criteria
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3.00 Credits
Biophysical descriptions and mechanisms of passive and excitable membranes, ion channels and pumps, action potential propagation, and synaptic transmission. Introduction to dynamics of single neurons and neuronal networks. Emphasis is on the experimental basis for modern research applications. Interdisciplinary aspects of biology and physics. Literature, problem sets, and student presentations. Prerequisites: undergraduate physics, calculus, and biology. 4 units, Win (Schnitzer, M)
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3.00 Credits
(Same as BIO 118.) Genetic principles and their experimental applications. Emphasis is on the identification and use of mutations to study cellular function. Prerequisite: Biology core. 5 units, Spr (Staff)
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3.00 Credits
Seminar. The logic of how neural circuits control behavior; how neural circuits are assembled during development and modified by experience. Emphasis is on primary literature. Topics include: neurons as information processing units; simple and complex circuits underlying sensory information processing and motor control; and development and plasticity of neural circuits. Advanced undergraduates with background in physical science, engineering, and biology may apply to enroll. Recommended: background in neuroscience. 3 units, not given this year
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3.00 Credits
(Same as APPPHYS 223.) Theoretical analysis of dynamical processes: dynamical systems, stochastic processes, and spatiotemporal dynamics. Motivations and applications from biology and physics. Qualitative approaches, asymptotics, and multiple scale analysis. Prerequisites: ordinary and partial differential equations, complex analysis, and probability or statistical physics. 3 units, alternate years, not given this year
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3.00 Credits
For graduate students and advanced undergraduates. Components of the immune system: structure and functions of antibody molecules; cellular basis of immunity and its regulation; molecular biology and biochemistry of antigen receptors and signaling pathways; genetic control of immunity and disease susceptibility. Emphasis is on key experimental approaches. Prerequisite for undergraduates: Biology or Human Biology core, or consent of instructor. 4 units, Aut (Jones, P)
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3.00 Credits
Supplement to 230. Corequisite: 230. 1 unit, Aut (Staff)
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3.00 Credits
Life histories as descriptions of reproduction, survival, and growth over the lives of individuals. Theoretical approaches to the dynamics and evolution of life histories and of populations with different life histories. Experimental data on natural populations and methods for their analysis. 3 units, Spr (Tuljapurkar, S), alternate years, not given next year
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4.00 Credits
(Same as BIO 132, BIOPHYS 232, MCP 232.) Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, and optical trapping. Limited enrollment. Recommended: basic physics, Biology core or equivalent, and consent of instructor. 4 units, Spr (Block, S; Schnitzer, M; Smith, S; Stearns, T)
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3.00 Credits
The largest megadiversity countries including Brazil and México. The conceptual basis of biodiversity conservation. Case studies. Topics include: habitat loss, threatened species, and hotspots; threats to the Amazon, Atlantic forest, Pantanal, and cerrado; impact of hunting; and the conflict between protected areas and parks. 3 units, Aut (Galetti, M)
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3.00 Credits
(Same as BIO 137.) Gene analysis, mutagenesis, transposable elements; developmental genetics of flowering and embryo development; biochemical genetics of plant metabolism; scientific and societal lessons from transgenic plants. Prerequisite: Biology core or consent of instructor. 3-4 units, Spr (Walbot, V)
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