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Course Criteria
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3.00 Credits
Application of genetics, cell biology, and molecular biology to the study of human diseases. Genomics, gene mapping, and molecular techniques. Animal models of disease. Chromosomal abnormalities, single-gene and multifactorial diseases, and epigenetics. Prerequisite: 210.
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3.00 Credits
Application of cell biology, molecular biology, and genetics to the study of cancer. Tumorigenesis; cellular oncogenes; growth factor signaling; tumor suppressor genes; apoptosis; metastasis and invasion. Prerequisite: 110A, 110B and 201.
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3.00 Credits
The theory of evolution at the molecular level. The evolution of DNA and RNA sequences, proteins, and genome structures will be studied using models from population genetics and comparative approaches. Molecular clocks, the evolution of gene regulation and globin genes, molecular phylogeny, and human evolution. Prerequisite: 210 and 205.
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3.00 Credits
Structure and function of nerve cells. Emphasis on electrical excitability, synaptic transmission, and sensory transduction. Cellular mechanisms underlying simple behaviors, sensory information processing, and learning and memory. Prerequisite: 110a-110b.
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3.00 Credits
Nerve cell interactions in neuronal networks of the central nervous system of animals and their impact for regulating behavior. Sensory systems, sensory-motor integration, central processing of information, neuronal-hormonal interactions; and brain anatomy and organization in invertebrates and vertebrates. Prerequisite: 110a-110b.
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3.00 Credits
Molecules of neural wiring, involving cell identity, pathfinding, synaptogenesis. Molecules of nerve cell communication, with relationship to drugs of addiction and abuse. Molecules of nervous system plasticity, and the mechanistic bases of learning and memory. Relation of these mechanisms to causes of human neurological diseases. Prerequisite: 110a-110b.
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3.00 Credits
Fundamental mechanisms of the major vertebrate physiological systems with an emphasis on humans. Special physiological adaptations of vertebrates to their environment (respiration of aquatic animals, birds, and deep diving mammals; salt balance in fresh and saltwater environments; altitude adaptation). Prerequisite: 201 or 220.
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3.00 Credits
Biochemistry of the expression, transmission, and maintenance of genetic information. DNA transcription, replication, recombination, and repair. Structural mechanisms and biological functions of DNA processing proteins. Prerequisite: 220.
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3.00 Credits
Principles of classical and molecular genetic analysis: mutation and recombination, mapping, and the application of genetic methodology to the study of complex systems. Special emphasis on modern genomic approaches. Prerequisite: 210.
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3.00 Credits
Application of genetics, biochemistry, molecular and cell biology to the study of viruses. Virus structure and classification, viral strategies of gene expression, genome replication, particle assembly. Host defenses against viruses. Comparisons with other infectious agents. Discussion of real-world outbreaks. Prerequisites: 210 and 201 or 226 or 265.
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