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Course Criteria
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4.00 Credits
Survey of current methods to study enzyme-catalyzed reactions, and application to examples from major enzyme, groups. Current topics in enzymology include abzymes and ribozymes, artificial enzymes, and enzymes, and enzyme engineering.
Prerequisite:
CHEM 3510 FOR LEVEL UG WITH MIN. GRADE OF C-
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4.00 Credits
The structural and chemical properties of nucleic acids and the resulting biological consequences. Topics include: 3D structures, conformation, protein/nucleic acid interactions, physical properties and chemical reactions, mutagenesis, damage/repair, and reconbination.
Prerequisite:
CHEM 3510 FOR LEVEL UG WITH MIN. GRADE OF C-
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2.00 Credits
Fundamental theory and practical application of X-ray diffraction to macromolecular structure determination, including protein crystallization and manipulation, data collection and reduction, phase solution, electron density interpretation, structural refinement.
Prerequisite:
CHEM 4850 FOR LEVEL UG WITH MIN. GRADE OF D-
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2.00 Credits
Hands-on training in protein crystallography. Laboratory projects include: protein crystallization, crystal manipulation and mounting, X-ray diffraction data collection, data reduction, structure solution, electron density interpretation, and refinement.
Prerequisite:
CHEM 4850 FOR LEVEL UG WITH MIN. GRADE OF D-
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2.00 Credits
Data Analysis of modern biophysical measurements related to the topics discussed in CHEM 4570 (Biophysical Chemistry), an introduction to scientific writing, and the preparation of scientific manuscripts. Six hours of laboratory per week.
Prerequisite:
CHEM 3520 FOR LEVEL UG WITH MIN. GRADE OF D-
Corequisite:
CHEM4570
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4.00 Credits
Principles and applications of physical chemistry as applied to biological macromolecules (i.e., proteins and nucleic acids in solution), including thermodynamics, kinetics and spectroscopy of macromolecular interactions.
Prerequisite:
PHYS 2080 FOR LEVEL UG WITH MIN. GRADE OF C- AND CHEM 3520 FOR LEVEL UG WITH MIN. GRADE OF C-
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4.00 Credits
Survey of biologically important metals and metal-ligand complexes, and the role of metal ions in proteins, metal ion transport and regulation, and metals in medicine.
Prerequisite:
CHEM 3520 FOR LEVEL UG WITH MIN. GRADE OF C-
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4.00 Credits
Symmetry, bonding theories, magnetism, and spectroscopic characterization of inorganic compounds are described. Coverage of spectroscopic techniques such as NMR, EPR, UV/VIS, IR, AND Mossbauer focus on applications to inorganic systems.
Prerequisite:
CHEM 3610 FOR LEVEL UG WITH MIN. GRADE OF C
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4.00 Credits
The organometallic chemistry of the transition metals, lanthanides and actinides is described. Synthesis, structure, bonding, and reactivity are considered. Applications in catalysis, bioinorganic, and materials chlemistry are discussed.
Prerequisite:
CHEM 3610 FOR LEVEL UG WITH MIN. GRADE OF C
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3.00 Credits
The application of modern theories to the elements and their inorganic compounds-advanced topics. Physical chemical principles are used throughout.
Prerequisite:
CHEM 3610 FOR LEVEL UG WITH MIN. GRADE OF C-
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