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Course Criteria
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1.00 Credits
10S: Arrange Offered in alternate years. Understanding of the molecular basis of human disease results from the exceptional power of genetic research technologies in the model organisms (worms, flies, fish and mice) and the universal nature of major genetic pathways in the animal kingdom. This course will offer integrated examination of the genetic, cellular, and molecular bases of the biology and pathology of development. The topics will be focused on the most interesting and informative human hereditary diseases for which the responsible genes have been identified. The developmental principles and pathways (e.g., Wnt signaling and colorectal cancer, sex determination and sex reversal, left-right asymmetry and human laterality disorders, DNA repair and Li-Fraumeni syndrome) and the model organisms we will use to illustrate them may vary somewhat from year to year. 1 hour of lecture and 3 hours of discussion per week. Prerequisite: permission of an instructor. Tevosian, Ahmed, Conradt, Ernst, Saito.
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3.00 Credits
All terms: Arrange An original individual, experimental, or theoretical investigation beyond the undergraduate level in genetics. This course is open only to graduate students, prior to passing their qualifying exam; it may be elected for credit more than once. This course carries one course credit and should be elected by students conducting research and also electing two or more other graduate or undergraduate courses. Dunlap and the staff of the Program.
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3.00 Credits
All terms: Arrange An original individual, experimental, or theoretical investigation beyond the undergraduate level in genetics. This course is open only to graduate students, prior to passing their qualifying exam; it may be elected for credit more than once. This course carries two course credits and should be elected by students electing only departmental colloquia in addition to research. Dunlap and the staff of the Program.
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3.00 Credits
All terms: Arrange An original individual, experimental, or theoretical investigation beyond the undergraduate level in genetics. This course is open only to graduate students, prior to passing their qualifying exam; it may be elected for credit more than once. This course carries three course credits and should be elected by students conducting research exclusively in any one term. Dunlap and the staff of the Program.
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3.00 Credits
F, W, S: Arrange All graduate students are required to enroll in Graduate Research Colloquium during each term of residence, except summer. In the Developmental Biology section, students will read and discuss original research papers that apply genetic, molecular, and/or genomic approaches to problems of metazoan development. All students will have frequent opportunities to lead discussions. The class ordinarily meets weekly. Not open to undergraduates. Saito.
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1.00 Credits
F, W, S: Arrange All graduate students are required to enroll in Graduate Research Colloquium during each term of residence, except summer. An essential element of scientific training is in the critical analysis and communication of experimental research in an oral format. Evaluation will be based on quality of the work described, quality of critical analysis, and on presentation style, including effective use of audio-visual materials. All students will be required to participate in at least one Journal Club/Research in Progress series. All students will make oral presentations that describe work from the current literature. This course will meet for a 1-hour discussion once per week. Not open to undergraduates. Fiering, Ernst.
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3.00 Credits
F, W, S: Arrange All graduate students are required to enroll in Graduate Research Colloquium during each term of residence, except summer. In the Cell Cycle and Metabolism section this journal club will focus on the interface between protein functional analysis and cell biology. Emphasis will be on papers in which enzymes with roles in the cell division cycle and/or metabolism are characterized using a mix of in vitro and in vivo approaches. Enrolled students will develop a literature screening method using Pubmed, Faculty of 1000 and/or Google Scholar. Each student will be responsible to read nine papers and present one paper per term. Papers will be circulated by email one week in advance of their discussion. To ensure that all students read and analyze the papers, the supervising faculty will call on students at random to present one figure per paper. Not open to undergraduates. Brenner.
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3.00 Credits
All terms: Arrange An original individual, experimental, or theoretical investigation beyond the undergraduate level in genetics. This course is open only to graduate students, subsequent to passing their qualifying exam; it may be elected for credit more than once. This course carries one course credit and should be elected by students conducting research and also electing two or more other graduate or undergraduate courses. Dunlap and the staff of the Program.
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3.00 Credits
All terms: Arrange An original individual, experimental, or theoretical investigation beyond the undergraduate level in genetics. This course is open only to graduate students, subsequent to passing their qualifying exam; it may be elected for credit more than once. This course carries two course credits and should be elected by students electing only departmental colloquia in addition to research. Dunlap and the staff of the Program.
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3.00 Credits
All terms: Arrange An original individual, experimental, or theoretical investigation beyond the undergraduate level in genetics. This course is open only to graduate students, subsequent to passing their qualifying exam; it may be elected for credit more than once. This course carries three course credits and should be elected by students conducting research exclusively in any one term. Dunlap and the staff of the Program.
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