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Course Criteria
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3.00 Credits
08F, 09F: 10; Laboratory W or Th 2:00-6:00 p.m. Chemistry 10 is a general chemistry course for students with a strong background in chemistry and mathematics who may have an interest in majoring in the sciences. The course will cover selected general chemistry topics important for higher level chemistry courses. These include thermodynamics, reaction kinetics, quantum mechanics, and bonding. Laboratory work will emphasize physico-chemical measurements and quantitative analysis. Chemistry 10 is open only to first-year students and enrollment is limited. Admission is by satisfactory performance on a general chemistry proficiency test given during Orientation. Adequate mathematics preparation, equivalent to Mathematics 3, is also required. Chemistry 10 is offered in the fall term and is the prerequisite equivalent to Chemistry 5/6. Students who successfully complete Chemistry 10 will also be granted credit for Chemistry 5, if they have not already been granted such credit. Prerequisite: Satisfactory performance on the general chemistry proficiency test and credit for Mathematics 3 or equivalent. Supplemental course fee required. Dist: SLA.
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3.00 Credits
10S: Arrange An introduction to the quantum mechanics of molecular systems. Approximate methods for calculating the electronic structure of molecules are discussed. Particular emphasis is placed on molecular orbital methods at the empirical, semi-empirical, and ab-initio levels. Evaluation of such methods for studies of molecular geometry, conformational problems, thermochemical data, and spectroscopic parameters is presented. Other topics considered include the electronic structure of hydrogen bonded systems and of excited states. Methods which include the effects of electron correlation are briefly outlined. Prerequisite: Chemistry 72 or equivalent, or permission of the instructor.
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3.00 Credits
10W: Arrange A study of optical spectroscopy including selected topics from amongst point group theory, vibrational spectra of polyatomic molecules, electronic and vibronic spectra of molecules and rotational spectra. May be offered on tutorial basis. Prerequisite: Chemistry 72 or equivalent, or permission of the instructor.
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3.00 Credits
10S: Arrange An introduction to the physical chemistry of macromolecules. Light scattering and other characterization techniques; thermodynamic and transport properties of macromolecular solutions. Structure-property correlations in amorphous and crystalline polymers. Prerequisite: Chemistry 71, or Chemistry 61 and permission of the instructor.
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3.00 Credits
09W: Arrange An introduction to the chemistry of organic polymers. The basic classes of polymerization will be discussed, with attention to kinetic and mechanistic details. Special emphasis will be placed upon living polymerization techniques and their application toward architectural control. Additional content will include, as time permits, topics of current interest such as: polymers in organic synthesis, polymeric assemblies and biomimetic/bioconjugate polymers. For selected topics, key articles from the chemical literature will be discussed. Prerequisite: Chemistry 52 or 58, or permission of the instructor.
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3.00 Credits
10W: Arrange Offered in alternate years This course is open to graduate, medical and advanced undergraduate students. It provides an introduction to toxicology as a discipline, with a focus on the molecular basis for toxicity of chemicals in biological systems. Major topics include: principles of cell and molecular toxicology, xenobiotic metabolism, molecular targets of cellular toxicity, genetic toxicology, chemical carcinogenesis, immunotoxicology, neurotoxicology, clinical toxicology, and quantitative risk assessment. Faculty lectures and discussion. Prerequisite: Undergraduate or graduate biochemistry, or permission of instructor.
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3.00 Credits
09W: Arrange Offered in alternate years This course is directed towards graduate students planning to use inorganic chemical analysis in their thesis work. The lectures and seminars focus on the theory and application of modern instrumental analysis and analytical chemistry. The theoretical backgrounds for a number of inorganic instrumental analytical methods are given, and examples of their application to problems of interest for analytical chemists working in the fields of earth science, chemistry, biology and environmental science are presented. The lectures cover ion chromatography, electrochemistry, atomic absorption, inductively coupled plasma optical emission and inductively coupled plasma mass spectrometry. The theory and concepts of analytical chemistry are provided along with statistical tools, uncertainty calculations and data treatment methods useful in analytical chemistry. Prerequisites: Chemistry 5 and Chemistry 6 or permission of instructor.
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3.00 Credits
09S: 10 Offered in alternate years A study of the structure, bonding, and chemical properties of organometallic compounds of the main group and transition elements. Applications to organic synthesis and homogeneous catalysis will be discussed, and organometallic compounds of the lanthanide and actinide elements may also be discussed. Prerequisite: Chemistry 64, or permission of the instructor.
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3.00 Credits
09F: 10 Offered in alternate years The role of metals in homogeneous and heterogeneous catalysis, with an emphasis on mechanisms of catalytic reactions. Applications to industrial processes, organic synthesis, and asymmetric synthesis will be discussed. Prerequisite: Chemistry 90, or permission of the instructor.
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3.00 Credits
10S: 10 Offered in alternate years The role of metal ions in biological systems. Topics include metal ion transport, storage, and interaction with proteins and nucleic acids; metalloproteins involved in oxygen transport and electron transfer; metalloenzymes involved in activation of oxygen and other substrates; and medicinal, toxicity, and carcinogenicity aspects of metals; as well as inorganic model chemistry of bioinorganic systems. Several physical methods are introduced, and their application to current research on the above topics is considered. Prerequisite: Chemistry 64, and Chemistry 41 or Biology 40, or permission of the instructor.
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