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Course Criteria
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3.00 Credits
09S: 9L This is an advanced course in statistics and experimental design, as applied to biological systems. There will be lectures and computer laboratories, regular homework assignments, and a major term project of statistical analysis. Topics covered include analysis of variance, generalized linear models and logistic regression, multivariate analysis methods, experimental design, and an introduction to Bayesian methods. Emphasis will be placed on the use of statistical programming for performing analyses. Offered in alternate years. Prerequisite: Biology 29. Dist: QDS. McPeek.
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3.00 Credits
10W: 2A This course is designed for the non-major. It will cover all aspects of dinosaur biology including their origin and evolution, phylogeny, behavior, physiology, and extinction. Because dinosaurs will be placed in their biological and geological contexts, other topics will include the geological record, the processes of fossilization, and vertebrate evolution in general. Particular attention will be paid to current debates including the origin of birds and mass extinction. The goal of this course is to teach the basic principles of evolutionary biology using dinosaurs as exemplars of evolutionary patterns and processes. Open to all students without prerequisite. Offered in alternate years. Dist: SCI. Peterson.
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3.00 Credits
08F: 2 Lectures dealing with the structure, function, organization, dynamics, and regulation of genes in higher eukaryotes and their viruses. Topics ranging from transposition of genes, to regulation of transcription, to targeted gene disruption in transgenic organisms will be covered. New topics in the literature will be included as well. Prerequisites: Biology 45 or permission of the instructor. Dist: SCI. Grotz.
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3.00 Credits
09W, 10W: 10A In this course we will explore how cancer develops on a cellular level. Using primary literature as a guide, we will examine the basic cellular processes malignant tumors exploit to promote their rapid, invasive growth and ultimately disease. Topics that will be considered include the genetic factors that initiate cancer cell formation, cell cycle regulation, programmed cell death, cell signaling, angiogenesis, cytoskeletal rearrangements as well as how current cancer therapies work on a cellular level. Prerequisites: Biology 12 and 13 and one from among Biology 38, 44, 45. Dist: SCI. Gladfelter.
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3.00 Credits
09W, 10W: 2A This course will focus on the molecular features of fungi and parasites that form the basis of strategies for adhering to and invading human host cells and tissues. The difficulties associated with development of drugs that neutralize eukaryotic fungi and parasites, but do not harm mammalian cells, heighten the importance of research on fungi and parasites and emphasize the unique aspects of eukaryotic pathogens compared to bacteria. Fungi, which are major pathogens in AIDS and other immunosuppressed patients, and parasites, such as malaria, which devastate human populations world-wide, will be emphasized. Prerequisites: Biology 12 and 13 and one from among Biology 40, 45, or 46. Dist: SCI. Sundstrom.
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3.00 Credits
08F, 09F: 10A; Laboratory: Arrange This course will study complex cellular machines using the approaches offered by biological, chemical, structural, and morphological techniques. Biological motors use ATP to perform work by interacting with a filamentous substrate. Dynein, kinesin, and myosin will be studied using cell biological, biochemical, and biophysical characterization of their activities. The course will then discuss the chemical kinetics and thermodynamics of motor proteins. X-ray diffraction and electron microscopy will provide examples that inform our understanding of motor chemistry and motor biology. The laboratory section will provide students with exposure to motor protein analysis using video enhanced fluorescence microscopy and other techniques. Prerequisites: Biology 12, Chemistry 51 (or 57) and one of the following (Biology 40, 44, 45, or Chemistry 41). Dist: SLA. Kull and Sloboda.
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3.00 Credits
09S, 09F: 10A This course will focus on how signals are transmitted from the cell surface into changes in cellular function. Detailed analysis of specific membrane receptors, second-messenger systems, and protein kinases will be presented as well as how these components are integrated into larger "systems" such as apoptosis, metabolic signaling, synaptic transmission, and sensory transduction. Particular emphasis will be on the biochemical analysis of the pathways and their individual components as well as how these pathways are impaired in certain disease states. The course will consist of lectures and weekly discussions of recent primary literature.Prerequisites: Biology 12 and 13, and at least one course from the following list: Biology 40, 44, 45, Chemistry 41. Dist: SCI. Rendi.
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3.00 Credits
Consult special listings
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3.00 Credits
09S, 10S: 2A This course will cover in depth one or more specific topics in cell biology such as cell division, chromosome structure and function, signal transduction, the cytoskeleton, membrane assembly, and intracellular protein targeting. Material will be presented in a manner designed to encourage student comments and to demonstrate how modern molecular, biochemical, immunological, and genetic techniques are employed to study problems in cell biology. Reading assignments will be taken from the current research literature. Prerequisites: Biology 12, 13 and one from among Biology 38, 44 or 45. Dist: SCI. Bickel.
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3.00 Credits
10S: 10A A seminar course that considers recent advances in specific areas of neurobiology. Topics to be discussed will be selected among ion channels, neurotransmitters, synaptic transmission, intracellular signaling pathways, synaptic connections, neuronal plasticity, brain biochemistry, behavioral neurobiology or developmental neurobiology. Offered in alternate years. Prerequisite: Biology 34. Dist: SCI. Vélez.
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