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Course Criteria
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3.00 Credits
09W, 10S: 11 This course will build upon the material presented in Biology 13 with in depth analysis of the molecular mechanisms underlying fundamental processes including DNA replication, transcription and translation in bacteria and eukaryotes. Key regulatory events that influence gene expression will be discussed including the function of promoters and enhancers, chromatin structure and epigenetics, RNA mediated silencing and mRNA processing. Emphasis will be placed on understanding how molecular techniques are used to elucidate critical aspects of these processes. Selected papers from the primary literature will be presented to illustrate current advances. Prerequisite: Biology 13. Dist SCI. Grotz.
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3.00 Credits
08F, 09F: 12; Laboratory: Arrange A lecture, discussion, and laboratory course considering the biology of microorganisms, with emphasis on bacteria. Topics such as structure, function, genetics, and metabolism of bacterial cells will be covered. The ecological role of various species of microorganisms will also be discussed. Prerequisite: Biology 12, 13, or 16. Dist: SLA. Guerinot, O'Toole.
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3.00 Credits
09W: 2 This course is an introduction to genomics, the study of biological organisms from a whole-genome perspective, and focuses on the genome of Homo sapiens and its relations to other genomes. Some of the topics discussed include: the sequencing, assembly and annotation of the human genome; the human gene complement; evolution of vertebrate and human genomes; comparative primate genomics; human nucleotide diversity and the human haplotype map; drug discovery in the post-genomic era; and a variety of experimental whole genome approaches for identifying global changes in gene regulation ( e.g. subtractive hybridization, micro-array analysis, serial analysis of gene expression and whole-genome bioinformatics). Offered in alternate years. Prerequisites: Biology 13 or 15. Dist: SCI. Erives.
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3.00 Credits
Not offered in the period from 08F through 10S. This course will consider philosophical issues pertinent to the biological sciences. Topics may include genetic determinism, biology and ideology, the nature of experiment in biological practice, adaptationism, the species problem, the nature of biology as a historical science, concepts of fitness and function, the units of selection debate, and phylogenetic inference. Open to all students without prerequisite. Dist: SCI. Dietrich.
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3.00 Credits
08F: 10ADiscussion: Arrange This course explores theory and data regarding properties of biological populations. Topics of lectures and analytical exercises include: descriptions of abundance, dispersion, and demographic schedules; applying life tables and matrix models to understand population growth and age structure; life history theory; influence of endogenous feedbacks and exogenous forces on population dynamics; spatial patterns and processes; and contributions of population ecology to applied issues in conservation, pest management, human demography, and the management of harvested populations. No student may receive course credit for both Biology 21 and Biology 51. Offered in alternate years. Prerequisites: Biology 16 and one course from among Biology 20-31. Dist: SCI. Ayres.
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3.00 Credits
09S: 2A Rigorous scientific methods are essential to the effective conservation of biodiversity and management of natural resources. This course will examine a range of analytical techniques employed in conservation and natural resource management. Techniques covered will include trend detection, population viability analysis, mark-recapture methods for the estimation of population size and demographic parameters (birth, death, migration), and movement and dispersal models. An important goal will be to understand the strengths and limitations of these methods and their practical applications. The emphasis will be on reading and discussing primary literature and working real-world examples using data collected on species of conservation and management significance. Students will be instructed in the use of a number of computer software packages useful in the analysis of population data. Grading will be based on exams, homework, and a term project. Prerequisites: Environmental Studies 20 or Biology 21/51, or permission of the instructor. Dist: TAS. Bolger.
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3.00 Credits
09W, 10W: D.F.S.P. The Biology Foreign Studies Program (Biology 55, 56, 57) exposes students, through intensive, full-immersion study, to Earth's most diverse biological communities. Biology 56 is a continuation of Biology 55; these courses comprise the first two-thirds of the FSP, and focus on land (tropical forests) and tropical freshwater ecosystems in Costa Rica. Biology 57 focuses on coral reef ecosystems in the Caribbean. Students are challenged to know, understand and appreciate the diversity of form and function in organisms, and the interactions that generate the often-spectacular patterns they see in the field. Habitats in Costa Rica include lowland rain forest, cloud forest, dry forest, montane forest, alpine paramo, streams and wetlands. The schedule is full, including fieldwork, laboratories, lectures and discussions, with emphasis on original research, mostly in small groups of 2-3. Faculty and advanced graduate TAs share field accommodations with students, and are in continuous contact as mentors, day and evening, throughout the program. Students master field and analytical methods (including hypothesis testing, statistical and software skills) for observational and experimental research. We pursue a great variety of research topics, including plant-pollinator and plant-herbivore interactions, processes driving coral reef structure (and coral reef decline), determinants of species distributions, animal behavior, and conservation ecology. Students practice the classic scientific approach: making observations, asking testable questions, generating hypotheses, developing experimental protocols, collecting data, making statistical inferences, writing scientific papers, and presenting seminars. Research papers are published in an annual book. Accommodations are at field stations in Costa Rica, and at a marine laboratory in the Caribbean. Prerequisites: Biology 16, one course from among Biology 20-28, 31; acceptance into program, Biology 15 and 29 recommended. Dist: SLA. Irwin.
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3.00 Credits
09W, 10W: D.F.S.P. A continuation of Biology 55. See Biology 55 for a description of the Biology Foreign Study Program. Prerequisites: Biology 55 (taken in same term). Dist: SLA. Peart.
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3.00 Credits
09W, 10W: D.F.S.P. Field and laboratory investigations of marine organisms and coral reef communities. Lecture and research topics include studies of algae, aquatic plants, invertebrates, and fish, with emphasis on populations, species interactions, community structure and energetics, and reef conservation and management. The course is based at the Little Cayman Research Center, Little Cayman Island. Scuba diving is optional. See Biology 55 for an overview of the Biology Foreign Study Program. Prerequisites: Biology 55 and 56 (taken in same term). Dist: SLA. Peart.
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3.00 Credits
09W: 10 This course will examine the various mechanisms structuring ecological communities of plants and animals. The course will consist of regular lectures, readings from the primary literature, and individual projects. Topics to be covered include simple two-species interactions (e.g. predation, competition, parasitism, mutualisms), simultaneous multispecies interactions, food web structure, regulation of species diversity on ecological and evolutionary time scales, community succession, and biogeography. Emphasis will be placed on the development of mathematical models and their relationship to empirical studies. Offered in alternate years. Prerequisites: Biology 15, 16 and one course from among Biology 20-31. Dist: SCI. McPeek.
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