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Course Criteria
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3.00 Credits
09S: 11 This course is an introduction to the biochemical aspects of human physiology. The adaptive responses of different human organ systems will be studied from the molecular, cellular, organ and systems level of organization. Topics to be covered include biological control systems (nerves, hormones, sensory and muscle cells) and coordinated body functions (circulation, respiration, osmoregulation, digestion). All the different organ systems working together during exercise will provide a framework for the final course synthesis. Offered in alternate years. Prerequisites: Biology 12 or 14. Dist: SCI. Vélez.
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3.00 Credits
08F, 09F: 10A This course is a survey of the history of genetics for students with some knowledge of genetics such as Biology 13 or 15. Proceeding from Galton to the present, this course will emphasize the main intellectual trends in genetics as well as the interconnection between genetics and society. Topics for discussion will include whether Gregor Mendel was a Mendelian, the importance of Thomas Hunt Morgan's Drosophila network, the relationship between eugenics and genetics, the effect of Atomic Energy Commission report on human genetics, and the impact of molecular biology. Prerequisite: Biology 13 or 15. Dist: SCI. Dietrich.
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3.00 Credits
09S, 10S: 10A The regulatory functions, physiology and molecular mechanisms of the endocrine system and related metabolic pathways will be explored with an emphasis on human and mammalian biology. Course requires a student paper on selected topics, stemming from an examination of the biology and pathobiology of these systems in health and disease. These topics will be drawn, in part, from timely publications in the biomedical literature. Prerequisite: Biology 12 and 13; Biology 14 recommended. Dist: SCI. Witters.
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3.00 Credits
09S, 10S: 12; Laboratory: Meets every M, W, F 1:45-2:50 This course provides in-depth coverage of the analysis of gene transmission and function. Biology 38 will build on material covered in Biology 13, emphasizing the use of model organisms to obtain information relevant to important problems in human genetics. Investigative laboratory exercises will reinforce and complement material covered in lecture. Prerequisite: Biology 13. Dist: SLA. Lambie.
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3.00 Credits
09W, 10W: 10A Computers and computer programs have become essential tools in modern molecular biology. As the amount of DNA and protein sequence data continues to grow, the use and understanding of these computational tools is becoming increasingly important. Deriving biological understanding from sequence data requires sophisticated computer analyses while demanding from molecular biologists the ability to interpret intelligently the results from these analyses. Not only can these programs provide the biologist with information about his or her sequence of interest, but a solid understanding of these tools can also be used to make predictions of biological phenomena that can be tested in the lab. This course will explore computational molecular biology through both lectures and hands-on computer experimentation through homework assignments. This course will discuss approaches to analyzing protein and DNA sequences and will foster an understanding of how to extract biologically relevant information from the numerous databases containing all this information. Topics will include basic computer architecture and operating systems, database design and searching, sequence comparisons, pattern discovery, genome comparisons, gene discovery, determining evolutionary relationships, RNA and protein structure predictions, data mining, and DNA array analysis. No computer programming experience is needed, but familiarity with using the Internet is recommended. Prerequisites: Biology 13. Dist: SCI. Gross.
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3.00 Credits
09S, 10S: 10A This course is designed for the humanities or social sciences major. It focuses on how our current understanding of genetic mechanisms has led to new biological insights and to the development of powerful technologies with far reaching implications for our society. It is the aim of this course to provide a solid understanding of the mechanisms of molecular genetics and to discuss implications of genetic engineering and related technologies to our every day lives. Although this course will focus on the science, we will also consider the ethical, political, human, and economic impacts of these technologies. Several guest lecturers will provide personal perspectives based on their experiences. The ultimate goal of the course is to provide an understanding of the biology and technology so that students can make informed decisions on issues that continually and increasingly arise in our society. Open to all students without prerequisite. Dist: SCI. Gross.
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3.00 Credits
08F, 09F: 10; Discussion W or Th 2:00-3:00 This course studies molecular structure and function from a biochemical point of view, emphasizing the biochemistry of proteins, lipids, and carbohydrates. Topics include protein structure and function, enzymes and enzyme kinetics, lipids and membranes, and carbohydrates and cell walls. The participation of these biomolecules in metabolism is also discussed, and focuses on the metabolic pathways of glycolysis, glucogenesis, fatty acid oxidation, amino acid catabolism, the TCA cycle, and oxidative phosphorylation. The course concludes with a look at the integration of metabolism in mammals. Students with credit for Chemistry 41 may not receive credit for Biology 40. Prerequisites: Biology 12 and Chemistry 52 or 58 or permission of the instructor. Dist: SCI. Schaller.
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3.00 Credits
09W, 10W: 9L This course will consider immunoglobulin structure, antigen-antibody reactions, complement, hypersensitivity, immunogenetics, immunodeficiency, tumor immunology and therapy, and autoimmunity. Prerequisite: Biology 12 or 13, or permission of the instructor. Dist: SCI. Fanger.
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3.00 Credits
08F, 09F: 9L An analysis of early cell and tissue development leading to organ differentiation. Fertilization, morphogenesis, and cell differentiation will be considered in terms of recent advances in developmental biology. Prerequisite: Biology 12 or 13. Dist: SCI. Erives.
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3.00 Credits
10W: 12 In this course students will extend their knowledge of cell biology by exploring several functional relationships between various fundamental cellular processes. For example, how do extracellular signals mediate cytoskeletal rearrangements that allow cells to move What is the relationship between mitochondrial function, oxidative stress, and controlled cell death What controls organelle biogenesis Discussions will emphasize modern experimental approaches for investigating cell function. Prerequisites: Biology 12 and 13. Dist: SCI. Smith.
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