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Course Criteria
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3.00 Credits
Not offered in the period from 08F through 10S A lecture and discussion course based on current research literature in the field of protein targeting and biogenesis and assembly of cell organelles. Topics will be introduced by a short lecture, which will be followed by discussion of current research papers from the field. Study guides, consisting of questions relating to the reading, will be used to focus discussion of research papers. Prerequisite: Permission of the instructor. Barlowe and associates.
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3.00 Credits
09S 10S: Arrange Each year Biochemistry 118 will focus on a different topic in genetics. Emphasis on reading and analyzing material from the primary literature. Prerequisite: Permission of the instructor. The staff.
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3.00 Credits
10S: ArrangeOffered in alternate years The role of metal ions in biological systems. Topics include metal ion transport, storage and interaction with proteins and nucleic acids, metalloproteins involved in oxygen transport and electron transfer, metalloenzymes involved in activation of oxygen and other substrates, and medicinal, toxicity and carcinogenicity aspects of metals, as well as inorganic model chemistry of bioinorganic systems. Several physical methods, including advanced spectroscopic techniques (EXAFS, Raman, ENDOR, NMR), are introduced and their application to current research on the above topics is considered. Prerequisite: Chemistry 41 or Biology 40, and Chemistry 64, or permission of the instructor. Pletneva and Wilcox.
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3.00 Credits
09S: ArrangeOffered as requested in alternate years. This course is designed for students with a solid fundamental background in Neuroscience. Students should have completed Medical Neuroscience or the equivalent as a prerequisite. Students without this background who wish to take this course may do so with permission of the instructor. Lectures will cover both classical papers relevant to cellular and molecular neuroscience as well as recent studies that highlight controversial and important findings in this field. Students will be required to read and critique original research papers. Discussion of these papers is an integral part of this course. Physiology graduate students registering for advanced elective credit should register for Physiology 118.
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3.00 Credits
All terms: Arrange This course is required to be taken at least once by all Biochemistry graduate students, based on the assertion that an essential element of graduate education is the experience gained in teaching other students. Such teaching experience is of particular relevance to students interested in academic careers. Students will conduct laboratory or discussion sessions in undergraduate courses under the supervision of the course faculty. The faculty and student teaching assistant work very closely to develop laboratory and discussion assignments. In some cases, the students are encouraged to present lectures for which they receive detailed feedback on their teaching style. In all cases students will receive instruction on effective teaching techniques through weekly preparation sessions. Topics for discussion include how to teach the material, how to run a discussion, how to evaluate student responses, and grading. Performance will be monitored throughout the term and appropriate evaluation, coupled with detailed suggestions for improvement, will be provided. This course is not open to undergraduates. The staff.
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3.00 Credits
All terms: Arrange An original individual experimental or theoretical investigation beyond the undergraduate level in biochemistry. This course is open only to graduate students prior to passing their qualifying exam; it may be elected for credit more than once. This course carries one course credit and should be elected by students conducting research and also electing departmental colloquia and one or more other courses. Barlowe and the staff of the Program.
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3.00 Credits
All terms: Arrange An original individual experimental or theoretical investigation beyond the undergraduate level in biochemistry. This course is open only to graduate students prior to passing their qualifying exam; it may be elected for credit more than once. This course carries two course credits and should be elected by students electing only departmental colloquia in addition to research. Barlowe and the staff of the Program.
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3.00 Credits
All terms: Arrange An original individual experimental or theoretical investigation beyond the undergraduate level in biochemistry. This course is open only to graduate students prior to passing their qualifying exam; it may be elected for credit more than once. This course carries three course credits and should be elected by students conducting research exclusively in any one term. Barlowe and the staff of the Program.
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3.00 Credits
F, W, S: Arrange This course is required of all students during each term of residence, except summer. An essential element of scientific training is in the critical analysis and communication of experimental research in an oral format. Evaluation will be based on quality of the work described, quality of critical analysis, and on presentation style, including effective use of audio-visual materials. Although minor variations in format exist among these two series, normally these series meet weekly and all students will be required to participate in at least one Journal Club presentation each term that describes work from the current literature and one Research in Progress presentation each academic year that describes their own research. This course is not open to undergraduates. The staff. Biochemistry 259, Actin Cytoskeleton Biochemistry 260, Structural Biology (Identical to Chemistry 264-Students should enroll in Chemistry 264) Biochemistry 261, Cancer Biology (S only) Biochemistry 263, Cell Biology
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3.00 Credits
All terms: Arrange An original individual experimental or theoretical investigation beyond the undergraduate level in biochemistry. This course is open only to graduate students subsequent to passing their qualifying exam; it may be elected for credit more than once. This course carries one course credit and should be elected by students conducting research and also electing departmental colloquia and one or more other courses. Barlowe and the staff of the Program.
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