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Course Criteria
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5.00 Credits
(204) First semester. Five credits. Four class periods and one 3-hour laboratory. Prerequisite or corequisite: CHEM 2444. Recommended preparation: MCB 2210 or MCB 2610. Not open for credit to students who have passed MCB 2000. The structure and function of biological macromolecules. The metabolism of carbohydrates, lipids, amino acids, proteins and nucleic acids. The regulation of metabolism and biosynthesis of biological macromolecules. An in-depth introduction intended for students planning to take advanced course work in biochemistry, biophysics, or other areas of molecular biology. A fee of $20 is charged for this course.
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2.00 Credits
(205) First semester, alternate years. Two credits. Prerequisite: MCB 2000 or 3010 or instructor consent. A thorough analysis of the inter-relationships of metabolic pathways in connection with human health and disease, including inherited metabolic diseases and the role of hormones in metabolic pathways.
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3.00 Credits
(222W) First semester. Three credits. Prerequisite: ENGL 1010 or 1011 or 3800. Recommended preparation: One 2000-level course in MCB. Molecular basis of human disease and strategies for developing therapeutic treatments. Applications of genetic, cellular, and biochemical information in treating disease states. Especially appropriate for students interested in biomedical research and the health profession.
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3.00 Credits
(211) First semester. Three credits. Prerequisite: BIOL 1107. Recommended preparation: MCB 2210. An introduction to the genetic, biochemical, and cellular mechanisms of the immune system. This course will address basic aspects of immune function, and will examine abnormal immune function associated with cancer, autoimmune disease, AIDS, and other immunological abnormalities.
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3.00 Credits
(220) Second semester. Three credits. Two 3-hour laboratory periods and a discussion/recitation period. Prerequisite or corequisite: MCB 4219, or six credits of college biology and consent of instructor. Not open for credit to students who have passed MCB 223. Analysis of principles of morphogenesis and differentiation.
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3.00 Credits
(246) Second semester. Three credits. Three lecture periods. Prerequisite: MCB 2610. Recommended preparation: MCB 2210 or 3010. Biological, biochemical, physical, and genetic characteristics of viruses, with an emphasis on molecular and quantitative aspects of virus-cell interactions.
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3.00 Credits
(212) Second semester. Three credits. Prerequisite: MCB 2410 or 2413. Recommended preparation: MCB 2000 or 3010. Methods and applications of genetic engineering, including gene manipulation and transfer techniques in prokaryotes and eukaryotes. Emphasis on applications of recombinant DNA technology in the elucidation of gene function. Consideration of recent technological developments in molecular genetics, such as cloning, gene therapy, the patenting and release of genetically engineered organisms, and societal issues related to these developments.
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2.00 Credits
(214) Second semester. Two credits. One fifty minute lecture period and one three hour laboratory session. Prerequisite: MCB 2410 or 2413. An introductory laboratory course in principles and techniques of DNA manipulation and identification. Course simulates independent research, using modern molecular genetics techniques. A fee of $20 is charged for this course.
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3.00 Credits
(290) First semester. Three credits. Prerequisite: MCB 2410 or 2413. DNA analysis in forensic science, with emphasis on molecular genetic technology in criminal investigations and issues surrounding the use of DNA evidence. Team-taught with forensic practitioners.
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3.00 Credits
(221) First semester. Three credits. Recommended preparation: At least one 2000-level course in MCB. Evolution of biomolecules, and application to molecular data analysis and the design of new molecules. Topics include prebiotic chemistry, origin of cells, selfish genes, molecular innovations, data bank searches, alignment of sequence and 3-D protein structures. Course includes lectures, discussions and computer lab exercises.
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