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Course Criteria
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0.00 Credits
Junior level undergraduate research. Prerequisite: Departmental good standing and permission of instructor. May be taken a maximum 3 times.
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3.00 Credits
This course provides an introduction to the fundamentals of fluid mechanics with an emphasis on biological systems. Topics of boundary layers, fluid properties, and laminar and turbulent flows will be covered. Cell motility and mechanics of cell movements in blood and cellular circuits will be covered. The course will have lecture and laboratory sessions. Prerequisites: Junior Standing, BIOL 1442, PHYS 1444, CHEM 2321, CHEM 2181, and MATH 3319.
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3.00 Credits
Hands-on experiments with use of transducers used for chemical, mechanical, electrical, and thermal biomedical measurements. Computer-based means of converting analog transducer output into digital form. Analysis of experimentally collected data including error analysis, repeatability, resolution, and functional specifications. Prerequisite: BIOL 1442, CHEM 2181, CHEM 2321, MATH 3319, and PHYS 1444.
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3.00 Credits
Introduction to properties of light, light-cell/tissue interactions, optical techniques, and optical instrumentation in the context of biophotonic medical applications. Topics that will be covered include fundamental properties of optical wave fields, basic properties and characterization of laser sources and detectors used in modern biomedicine, interferometery, linear and nonlinear light-tissue interactions exploited for biomedical imaging and sensing applications, and spectroscopy. Prerequisite: BIOL 1442, MAE 3319 (or EE 3317), MATH 3319, and PHYS 1444.
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3.00 Credits
Introduction to the anatomy of fluorescence microscopy and the physical principles of its operation; confocal and multi-photon microscopy; molecular imaging applications based on Forster Resonance Energy Transfer (FRET), Fluorescence Lifetime Imaging (FLIM), Fluorescence Correlation Spectroscopy (FCS), Fluorescence Recovery After Photobleaching (FRAP) and Total Internal Reflection Fluorescence (TIRF) Microscopy. Prerequisite: BIOL 1442, MAE 3319 (or EE 3317), MATH 3319, and PHYS 1444.
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3.00 Credits
Introduction to the science and technology behind tissue optical imaging systems and their design requirements for different clinical applications; diffuse optical tomography; fluorescence tomography; bioluminescence tomography; multi-modality imaging. Prerequisite: BIOL 1442, MAE 3319 (or EE 3317), MATH 3319, and PHYS 1444.
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3.00 Credits
Fundamental principles of bioinstrumentation, including operational amplifiers and instrumentation amplifiers; measurements of biopotentials; signals and noise in biological systems; mechanical transducers; resistive, inductive, capacitive transducers; measurement of temperature, blood pressure and flow; electrical safety. Prerequisite: BE 3380, EE 3317 (or MAE 3319), MATH 3319, and PHYS 1444.
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3.00 Credits
This course introduces basic medical imaging modalities, including X-ray Computed Tomography (CT), Nuclear Medicine Imaging (PET and SPECT), Magnetic Resonance Imaging (MRI), and image-guided interventions. Through this course, the students will learn fundamental knowledge on how medical images are obtained and how they can be used for diagnosis, therapy, and surgery. Prerequisite: BE 3380, EE 3317 (or MAE 3319), MATH 3319, and PHYS 1444.
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3.00 Credits
Fundamental techniques for extraction of useful information from signals acquired from biological systems. Topics include time and frequency domain analysis, cross correlation, spectrum analysis, and convolution. Design of finite impulse response (FIR) and infinite impulse response (IIR) filters for processing biological signals are described. Examples include cardiac, respiratory, and biomechanical movements. Prerequisite: BE 3380, EE 3317 (or MAE 3319), MATH 3319, PHYS 1444
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3.00 Credits
Fundamentals of cell/extracellular matrix interactions in terms of cell spreading, migration, proliferation and function; soft and hard tissue wound healing and nerve regeneration; polymer scaffolding materials and fabrication methods; cell-polymer interactions; in vitro and in vivo tissue culture and organ replacement. Prerequisite: BIOL 1442, CHEM 4311 (or concurrent enrollment), MATH 3319, and PHYS 1444.
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