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Course Criteria
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3.00 Credits
Prerequisite(s): CBE 400. Design of a chemical process based on recent advances in chemical engineering technology. Weekly design meetings with faculty advisor and industrial consultants. Comprehensive design report and formal oral presentation.
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3.00 Credits
Prerequisite(s): CBE 353. Dynamics and control of linear single-input, single output (SISO) systems in chemical processes. Laplace transforms. Dynamic responses of linear systems to inputs in time and transform domains. Frequency domain analysis. Feedback control strategies. Stability. Controller tuning. Advanced control, including cascade and feed forward control. Introduction to multiple-input, multiple-output (MIMO) control.
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3.00 Credits
Prerequisite(s): CBE 150 or equivalent. Junior/Senior Standing in Engineering. An overview of several important aspects of modern biotechnology from a chemical engineering perspective: DNA, enzymes and other biomolecules, cell growth and metabolism, cellular and enzymatic reactors, bioseparation techniques, molecular genetics, and biotransport processes.
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3.00 Credits
Prerequisite(s): CBE 479 or Permission of the Instructor. Laboratory methods in biochemical and genetic engineering. Molecular cloning techniques. DNA amplification and sequencing techniques. Culture of microbial cells. Recovery and purification of a microbial product enzyme. Measurement of enzyme activity.
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3.00 Credits
This course is designed as an overview of probability and statistics including linear regression, correlation, and multiple regression. The program will also include statistical quality control and analysis of variance with attention to method of analysis, usual method of computation, test on homogeneity of variances, simplifying the computations, and multifactor analysis.
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3.00 Credits
This course focuses on synthesis, characterization, microstructure, rheology, and structure-property relationships of polymers, polymer directed composites and their applications in biotechnology. Topical coverage includes: polymer synthesis and functionalizaiton; polymerizaiton kinetics; structure of glassy, crystalline, and rubbery polymers; thermodynamics of polymer solutions and blends, and crystallization; liquid crystallinity, microphase separation in block copolymers; polymer directed self-assembly of inorganic materials; biological applications of polymeric materials. Case studies include thermodynamics of block copolymer thin films and their applications in nanolithography, molecular templating of sol-gel growth using block copolymers as templates; structure-property of conducting and optically active polymers; polymer degradation in drug delivery; cell adhesion on polymer surface in tissue engineering.
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3.00 Credits
Nonlinear systems: numerical solutions of nonlinear algebraic equations; sparse matrix manipulations. Nonlinear programming and optimization; unconstrained and constrained systems. Lumped parameter systems: numerical integration of stiff systems. Distributed parameter systems: methods of discretization. Examples from analysis and design of chemical and biochemical processes involving thermodynamics and transport phenomena.
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3.00 Credits
This course will introduce students to the important concepts invovled in industrial catalytic processes. The first part of the course will review some of the fundamental concepts required to describe and characterize catalysts and catalytic reactions. The majority of the course will then focus on applying these concepts to existing heterogeneous catalysts and catalytic reactions, including discussion of the actual process design and engineering. Descriptions of some homogeneously catalyzed processes like polymerization and the synthesis of acetic acid will also be covered.
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3.00 Credits
This course provides an introduction to the quantitative methods used in characterizing and engineering biomolecular properties and cellular behavior, focusing primarily on receptor-mediated phenomena. The thermodynamics and kinetics of protein/ligand binding are covered, with an emphasis on experimental techniques for measuring molecular parameters such as equilibrium affinities, kinetic rate constants, and diffusion coefficients. Approaches for probing and altering these molecular properties of proteins are also described, including site-directed mutagenesis, directed evolution, rational design, and covalent modification. Equilibrium, kinetic, and transport models are used to elucidate the relationships between the aforementioned molecular parameters and cellular processes such as ligand/receptor binding and trafficking, cell adhesion and motility, signal transduction, and gene regulation.
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3.00 Credits
Application of chemical engineering principles to analysis of eukaryotic cell biological phenomena, emphasizing receptor-mediated cell function. Topics include receptor/ligand binding kinetics and trafficking dynamics, growth factor regulation of cell proliferation, cell adhesion, cell migration and chemotaxis, and consequences of these in physiological situations such as the immune and inflammatory responses, angiogenesis, and wound healing.
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