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Course Criteria
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3.00 Credits
Living World Sector. All classes. Thompson-Schills. Prerequisite(s): PSYC 001 or BIBB/PSYC 109. The study of the neuronal systems that underlie human perception, memory and language; and of the pathological syndromes that result from damage to these systems.
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3.00 Credits
Schmidt, M./Abel/Peachey. Prerequisite(s): BIOL 101 and 102, or BIOL 121; PHYS 102 or 151 strongly recommended. Lab fee $150. (3hrs. lec., 3hrs. lab, 1.5 c.u.). Cellular physiology of neurons and excitable cells; molecular neurobiology and development. Topics include: action potential generation; synaptic transmission; molecular and physiological studies of ion channels; second messengers; simple neural circuits; synaptic plasticity; learning and memory; and neural development.
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3.00 Credits
Flanagan-Cato. Prerequisite(s): BIBB 109, one year of Biology, or Permission of Instructor. This course is designed to examine the various roles played by the nervous and endocrine systems in controlling both physiological processes and behavior. First, the course will build a foundation in the concepts of neural and endocrine system function. Then, we will discuss how these mechanisms form the biological underpinnings of various behaviors and their relevant physiological correlates. We will focus on sexual and parental behaviors, stress, metabolism, neuroendocrine-immune interactions, and mental health.
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3.00 Credits
Heerding. Prerequisite(s): BIBB 109 or Permission of Instructor. This lecture course is designed to introduce the student to the functioning of the autonomic nervous system (ANS), which is critically involved in the maintenance of body homeostasis through regulation of behavior and physiology. The course will begin with a review of the basic anatomy and physiology of the ANS including the sympathetic, parasympathetic and enteric divisions. The mechanisms by which the ANS regulates peripheral tissues will be discussed, including reflex and regulatory functions, as will the effect of drugs which modulate ANS activity. The role of the ANS in regulating behavior will be addressed in the context of thirst, salt appetite and food intake. Finally, the course will cover the result of over-activation of the sympathetic nervous system as manifested in chronic stress. (PSYC125) Drugs, Brain and Mind. (B) Peoples. Prerequisite(s): BIBB 209, Intro Biology and Intro Psychology. The course will begin with a review of basic concepts in pharmacology including: routes of drug administration, drug metabolism, the dose response curve, tolerance and sensitization. Following a brief overview of cellular foundations of neuropharmacology (cell biology, synaptic and receptor function), the course will focus on various classes of drugs used to treat neuropsychiatric disorders including, among others, depression, schizophrenia and anxiety. We will additionally consider mechanisms mediating the mind-altering, addictive and neurotoxic effects of abused drugs.
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3.00 Credits
Miselis. Prerequisite(s): BIBB 109 or permission of instructor. Lab Fee: $100. A laboratory course designed to familiarize the student with the fundamental gross and histological organization of the brain. The mammalian brain will be dissected and its microscopic anatomy examined using standard slide sets. Comparative brain material will be introduced, where appropriate, to demonstrate basic structural-functional correlations.
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3.00 Credits
Dinges. Prerequisite(s): BIBB 109 or Permission of Instructor. Topics to be covered include basic principles of chronobiology; neuroscience mechanisms of circadian rhythms and sleep; phylogeny and ontongeny of sleep; human sleep and sleep disorders; circadian dysfunction; circadian and sleep homeostatic influences in human health and safety.
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3.00 Credits
Staff. Prerequisite(s): BIOL 102 or 122 and BIBB 109, or Permission of Instructor. This course will focus on cellular and molecular mechanisms of the organogenesis of the central nervous system. A goal of the course will be to understand the form, function and pathology of the adult nervous system in terms of antecedent developmental processes.
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3.00 Credits
Standing Faculty. Prerequisite(s): BIBB 109 and permission of the Director. Individual research of an experimental nature with a member of the standing faculty leading to a written paper. The grade is based primarily on a serious term paper describing original research carried out by the student. Students must submit a proposal prior to registering. During the semester, students must attend two seminars led by the BBB Director or Associate Director to discuss planning an independent research project, ethical concerns in research and writing a scientific paper. Attendance at the meetings is mandatory. Students wishing to do research in hospitals with investigators who are not standing faculty at Penn should inquire about College 99 at the College Advising Office. Students doing more than one credit of independent study will be required to present a poster at the annual BBB Symposium.
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3.00 Credits
Ulm. Prerequisite(s): BIBB 109. Previously BIBB 390. Fundamentals of Behavioral Medicine concerns itself with the description of ideology, disease and treatment from the perspective of a functional analyses. It is the intent of this course to extend the traditional structural analysis that traditional medicine provides.
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3.00 Credits
Newberg. Prerequisite(s): BIBB 109. The ability to utilize different imaging techniques in disciplines such as psychology, psychiatry, neurology, and cognitive neurosciences is a growing field and presents many interesting problems and possibilities. This course is an upper level seminar course for individuals pursuing one of the above mentioned fields and/or premedical course work. The course would provide a detailed overview of functional brain imaging and its potential uses. Issues regarding advantages and disadvantages of different modalities, study design image analysis and interpretation, and how each of these relates to various neurological and psychological phenomena will be discussed. The classes will cover the following specific topics in this general time frame: Introduction to functional brain function, basics of nuclear medicine imaging (including instrumentation, image acquisition, and radiopharmaceuticals for positron emission tomography and single photon emission computed tomography), imaging of neurological disorders, imaging of psychological disorders, introduction to activation studies, image analysis and statistical problems, study design, literature review, journal article presentation, tour of Penn imaging facilities, interpretation of imaging studies, implications for clinical and research, and implications for understand the human mind and consciousness.
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