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  • IMUN 699: Laboratory Rotation

    3.00 Credits
    University of Pennsylvania

    Various Immunology Group Faculty. Prerequisite(s): Permission of instructor and immunology chair. Laboratory research conducted under a faculty advisor. Three different rotations covering usually the fall semester of the first year through the fall semester of the second year are required of all Immunology Ph.D. students.Students will defend the rotation research in their Preliminary Exams.
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  • IMUN 999: Independent Study

    3.00 Credits
    University of Pennsylvania

    Terri Laufer, M.D. Prerequisite(s): Permission of Graduate Group Chairperson. 1 h. 1 c.u.; taught Fall term. Directed readings, with or without laboratory research, in various fields of immunology arranged individually with members of staff. Mandatory attendance at weekly research presentations by graduate group faculty.
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  • INSC 573: Neuroscience Core III

    3.00 Credits
    University of Pennsylvania

    Larry Palmer, Michael Nusbaum. This course provides an introduction to what is known about how neuronal circuits solve problems for the organism and to current resarch approaches to this question. Topics include: vision, audition, olfaction, motor systems, plasticity, and oscillations. In addition, the course aims to provide an overview of the structure of the central nervous system. A number of fundamental concepts are also discussed across topics, such as: lateral inhibition, integration, filterting, frames of reference, error signals, adaptation. The course format consists of lectures, discussions, readings of primary literature, supplemented by textbook chapters and review articles.
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  • INSC 574: Neuromorphing:Building Brains in Silicon

    3.00 Credits
    University of Pennsylvania

    Kwabena Boahen. Prerequisite(s): Students with advanced knowledge in neurobiology but rudimentary knowledge in electrical engineering or vice versa are welcome. Biology students should have (1) Biophysics (BE205/CHEM221) or (2) Basic Neuroscience (INSC 591). Systems Neuroscience (INSC 598) and Computational Neuroscience (INSC 594/BE 520) are highly recommended. Engineering students should have (1) Solid-State Device Physics (EE218) or Solid-State Circuits (EE319). VLSI Chip Design (EE560/562/564) is highly recommended. Students do no need to have all these prerequisites to take this course. Please contact the instructor if you have any questions. We model the structure and function of neural systems in silicon using very large scale integration (VLSI) complementary metal-oxide-semiconductor (CMOS) technology. To build these neuromorphic systems, we proceed from the device level, through the circuit level, to the system level. At the device level, we mimic electrodiffusion of ions through membrane channels with electrodiffusion of electrons through transistor channels. At the circuit level, we derive minimal implementations of synaptic interaction, dendritic integration, and active membrane behavior. At the system level, we synthesize the spatiotemporal dynamics of the cochlea, the retina, and early stages of cortical processing.
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  • INSC 575: Neurobiology of Learning and Memory

    3.00 Credits
    University of Pennsylvania

    Ted Abel. This course focuses on the current state of our knowledge about the neurological basis of learning and memory. A combination of lectures and discussions will explore the molecular and cellular basis of learning in invertebrates and vertebrates from a behavioral and neural perspective.
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  • INSC 576: Neuropsychopharmacology

    3.00 Credits
    University of Pennsylvania

    Irwin Lucki. Neuropsychopharmacology provides an oveview of the neurobiology of major neuropsychiatric illnesses. The course is divided into four modules related to behavioral disorders or disciplines. The specific modules covered are: affective disorders, substance abuse, schizophrenia, and behavioral genetics. The modules present material that integrates clinical and basic neurobiology approaches to research of complex behavioral disorders. Each module covers a specific area using the following format: clinical features basic and clinical neuroscience studies relevant to understanding the pathobiology and mechanisms of treatment of each set of disorders case presentations or outside speakers.
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  • INSC 578: Advance Topics in Behavioral Genetics

    3.00 Credits
    University of Pennsylvania

    Ted Abel/Maja Bucan. This course focuses on the use of genetic techniques to study the molecular and cellular bases of behavior. Particular emphasis will be given to the role of genetic approaches in understanding the biological processes underlying learning, memory storage, circadian rhythms, and drug abuse. Reverse genetic approaches utilizing gene knockout and transgenic technology, as well as forward genetic approaches using mutagenesis and quantitative genetic techniques, will be discussed.
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  • INSC 579: Synaptic Transmission

    3.00 Credits
    University of Pennsylvania

    Tom Parsons. Prerequisite(s): core II and core III or permission of the instructors. This seminar course will involve critical reading and discussion of classic and modern papers in synaptic physiology. Approximately half the time will be spent on the neuromuscular junction, with the balance covering central synapses.
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