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Course Criteria
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3.00 Credits
Lochner, Staff Content: Contemporary biochemical techniques introduced in a project-based format. Protein purification using both recombinant DNA techniques and classical tools such as affinity chromatography; functional characterization of the purified protein. Cellular metabolic responses and transmembrane signaling reactions studied using HPLC, radioisotope studies, enzyme analyses. Prerequisite: Chemistry 330 or 335 (may be taken concurrently). Taught: Annually, 2 semester credits.
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3.00 Credits
Loening, Tufte Content: Experimental methods and instrumentation in the physical sciences. Design experiments, construct instrumentation, make measurements, and analyze and interpret data in order to reach meaningful conclusions. Discussion and use of modern experimental techniques, including analog and digital electronics, many types of sensors, computerized data acquisition, spectroscopy (atomic, fluorescence, and infrared), mass spectrometry, and chromatography. Final student-designed project provides opportunities for interdisciplinary investigations. This course is taught in conjunction with Physics 201. Credit may not be earned for both Chemistry 355 and Physics 201. Prerequisites: Chemistry 120 and Physics 141 or 151, or consent of instructor. Corequisites: Chemistry 220 and Physics 142 or 152, or consent of instructor. Taught: Annually, 4 semester credits.
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3.00 Credits
Balko, Loening Content: Laboratory course to demonstrate the principles of physical chemistry and to develop research aptitude in chemistry. Investigation of thermochemistry, phase equilibria, kinetics, spectroscopy, and solid-state studies using techniques such as calorimetry, UV-visible, IR, NMR, Mass spectroscopies, and diffraction. Attendance at departmental seminars required. Lecture, laboratory, oral presentations. Prerequisite: Chemistry 310 or 320 (may be taken concurrently). Taught: Annually, 2 semester credits.
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3.00 Credits
Bentley, Kuo Content: Introduction to classical and modern techniques for synthesizing inorganic compounds of representative and transition metal elements and the extensive use of IR, NMR, Mass, and UV-visible spectroscopies and other physical measurements to characterize products. Syntheses and characterization of inorganic and organic materials/polymers are included. Attendance at departmental seminars required. Lecture, laboratory, oral presentations. Prerequisite: Chemistry 220. Taught: Annually, 2 semester credits.
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3.00 Credits
Staff Content: Preparation and delivery of a seminar with accompanying abstract and bibliography. The seminar focus is either on a relevant topic in the chemical literature or, for students pursuing senior and honors research, on the thesis proposal. Prerequisite: Senior standing. Taught: Each semester, 1 semester credit.
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3.00 Credits
Bentley Content: Modern concepts of inorganic and transition metal chemistry with emphasis on bonding, structure, thermodynamics, kinetics and mechanisms, periodic and family relationships. Atomic structure, theories of bonding, symmetry, molecular shapes (point groups), crystal geometries, acid-base theories, survey of familiar elements, boron hydrides, solid-state materials, nomenclature, crystal field theory, molecular orbital theory, isomerism, geometries, magnetic and optical phenomena, spectra, synthetic methods, organometallic compounds, cage structures, clusters, lanthanides, actinides. Prerequisite: Chemistry 320 or consent of instructor. Taught: Annually, 4 semester credits.
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3.00 Credits
Kuo Content: Bioorganic chemistry for selected medicinal compounds. Biophysical and chemical concepts of drug-receptor interactions and drug action. Biochemical basis for drug action elucidated in the context of fundamental organic mechanisms. Prerequisite: Chemistry 220. Taught: Annually, 2 semester credits.
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3.00 Credits
Duncan Content: Modern approach to the study of the interrelationships between structure and reactivity in organic molecules: Advanced stereochemistry; energy surfaces and kinetics; advanced electronic structure theory, including computational methods; thermal pericyclic reactions. Subject to interests of students and instructor, substitute physical organic topics might include, among others: Photochemistry, linear free-energy relationships, catalysis, electronic organic materials, molecular recognition, supramolecular chemistry. Prerequisite: Chemistry 220 Corequisite: Chemistry 320 or consent of instructor. Taught: Alternate years, 2 semester credits.
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3.00 Credits
Loening Content: Advanced topics in nuclear magnetic resonance spectroscopy, with an emphasis on structural biology applications. Fundamental NMR theory, multidimensional methods, heteronuclear experiments, correlation spectroscopy, the nuclear Overhauser effect, chemical exchange, protein structure determination, protein dynamics. Prerequisite: Chemistry 220. Chemistry 320 and/or 330 are recommended. Taught: Alternate years, 2 semester credits.
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3.00 Credits
Staff Content: Experimental and/or theoretical research on an advanced topic of current significance in chemistry. Students present their thesis proposals in an early fall seminar and detail results of their investigations in a thesis in the spring. Prerequisites: Senior standing. Consent of instructor. Taught: Annually, 4 semester credits each semester of the senior year.
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