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Course Criteria
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2.00 Credits
Chemical analysis based on modern instrumentation. Chromatographic, electrochemical, and spectroscopic methods. Prerequisite(s): CHM 201, 201L; (CHM 302 or 304).
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2.00 Credits
Course to accompany CHM 415. Two three-hour laboratory sessions each week. Prerequisite(s): CHM 201L; CHM 302 or equivalent.
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3.00 Credits
An advanced course in modern inorganic chemistry. Atomic structure, principles of bonding and structure, acid-base chemistry, periodicity, coordination compounds, nonaqueous solvents, electrochemistry, molecular symmetry, organometallic compounds, and the chemistry of selected representative elements. Prerequisite(s): CHM 314. Corequisite(s): CHM 302 or 304.
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1.00 Credits
Laboratory course dealing with the synthesis and characterization of inorganic and organometallic compounds. Topics include vacuum and inert atmosphere techniques, separation and purification, spectroscopic characterization, X-ray diffraction, magnetic moment, and conductance measurements. Prerequisite(s): CHM 201L, 314L. Corequisite(s): CHM 417.
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3.00 Credits
The fundamental aspects of the chemistry and biochemistry of carbohydrates, lipids, proteins, and nucleic acids. Enzymology, protein purification, bioenergetics, metabolism of carbohydrates, lipids, amino acids, nucleotides and nucleic acids, elementary molecular biology, and control processes are described. Acceptable preparation for medical school. Prerequisite(s): CHM 314.
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3.00 Credits
Mechanistic fundamentals of the biosynthesis and transformation of organic natural products, with special emphasis on medicinal compounds, toxins, pheromones and other secondary metabolite structures. Prerequisite(s): (CHM 314, 314L) or equivalent.
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3.00 Credits
The chemical mechanisms of action of the major drug classes will be surveyed with particular emphasis on the facets of organic chemistry that control drug-receptor interactions, metabolism and mechanisms of toxicity and resistance. First term. Prerequisite(s): CHM 314; (CHM 420 or 451).
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3.00 Credits
Discussion of the chemistry and biochemistry of carbohydrates, amino acids, proteins, and nucleic acids, including health-science and methodologic aspects. Descriptions of enzymology, protein purification, and carbohydrate metabolism related to such topics as bioenergetics, membranes, and disease processes. Recommended for students desiring entry into graduate and professional schools. Prerequisite(s): CHM 201, 314.
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3.00 Credits
Discussion of selected topics in bioenergetics, and metabolism of lipids, amino acids, porphyrins, nucleic acids, and proteins. Current aspects of nutrition, biochemical genetics, endocrinology, regulation, and genetic engineering addressed and related to health-science topics as time permits. Suitable preparation for medical school. Prerequisite(s): CHM 451.
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3.00 Credits
Introduction to drug target selection, lead compound discovery, and application of structure-activity relationships and computational chemistry towards refinement and optimization of lead compounds and their derivatives. Use of molecular graphics software and publicly available macromolecular structure databases will provide the foundation for evaluating macromolecular models of drug targets and allow a hands-on exploration of the structure/function relationships of proteins that have been successful targets of rational drug design.
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